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Van Duyne

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http://chemgroups.northwestern.edu/vanduyne/research_overview.htm

Raman ºÍ Surface-Enhanced Raman Spectroscopy

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1£© Surface-Enhanced Raman Spectroscopy
2£© Surface Plasmon Resonance and Localized Surface Plasmon Resonance Spectroscopy
3£© Resonant Rayleigh Scattering Spectroscopy
4£© Some Images of our Specialized Equipment

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31Â¥2008-01-15 12:43:49
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Norman J. Dovichi

¡¾µ¼Ê¦ÐÕÃû¡¿Norman J. Dovichi
¡¾Ñо¿·½Ïò¡¿Ultrasensitive Bioanalytical Research
       ÊÖ¶Î----ëϸ¹ÜµçÓ¾·ÖÀë¡¢¼¤¹âÓÕµ¼Ó«¹â¼ì²â(°üÀ¨ÆäËû¹âÆ×¼¼Êõ)
       ¶ÔÏó----ÉúÎï·Ö×Ó(DNA, proteins, carbohydrates, and lipids)
¡¾ËùÔÚµ¥Î»¡¿Department of Chemistry, University of Washington
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¡¾ÁªÏµµØÖ·¡¿http://faculty.washington.edu/dovichi/UBUBTpage/norm/norm.html
http://faculty.washington.edu/do ... ontact/contact.html

E-mail: dovichi@chem.washington.edu
Phone: +1-206-543-7835
Fax: +1-206-685-8665
Mail: Department of Chemistry
University of Washington
Seattle, WA 98195-1700 USA
32Â¥2008-01-19 19:58:37
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Prof. James F. Rusling

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¡¾µ¼Ê¦ÐÕÃû¡¿James F. Rusling
¡¾Ñо¿·½Ïò¡¿ÉúÎï·ÖÎö£¬µç·ÖÎö
¡¾ËùÔÚµ¥Î»¡¿Department of Chemistry, University of Connecticut
¡¾Ñо¿³É¹û¡¿Publications
http://web.uconn.edu/rusling/pubs2008.html
270. Erwin V. Fundador, Dharamainder Choudhary, John B. Schenkman and James F. Rusling, Accurate DNA Fragment Sizing By CE-LIF Array For Detection Of Sequence Specificity Of DNA Damage, Anal. Chem., 2008, in press.
269. James F. Rusling, Eli G. Hvastkovs, Dominic O. Hull and John B. Schenkman, Biochemical applications of ultrathin films of enzymes, polyions and DNA (feature article), Chem. Commun., 2008, 141 - 154.
268. James F. Rusling, Bingquan Wang, and Sei-eok Yun, Chapter 1.4. Electrochemistry of Redox Enzymes In P. N. Bartlett, Ed., Handbook of Bioelectrochemistry, John Wiley, N. Y. 2008, in press.
267. Besnik Bajrami, Eli G. Hvastkovs, Gary Jensen, John B. Schenkman, and James F. Rusling, Enzyme-DNA Biocolloids for Reactive Metabolite and DNA Adduct Detection by Chromatography-Mass Spectrometry, Anal. Chem., 2008, in press.
266. Minjeong So, Eli G. Hvastkovs, Besnik.Bajrami, John B. Schenkman, and James F. Rusling, Electrochemical Genotoxicity Screening for Arylamines Bioactivated by N-acetyltransferase, Anal. Chem., 2008, in press.
265. Vito Cataldo, Abhay Vaze, and James F. Rusling, Improved Detection Limit and Stability of Amperometric Carbon Nanotube-based Immunosensors by Crosslinking Antibodies with Polylysine, Electroanalysis, 2007, 20, 115 -122.
264. Haiyun Lu, James F. Rusling, Naifei Hu, Protecting Peroxidase Activity of Multilayer Enzyme-Polyion Films Using Outer Catalase Layers, J. Phys. Chem. B, 2007, 111, 14378-14386.
263. Eli G. Hvastkovs, Minjeong So, Sadagopan Krishnan, Besnik Bajrami, Maricar Tarun,  Ingela Jansson, John B. Schenkman, and James F. Rusling, Electrochemiluminescent Arrays for Cytochrome P450-activated Genotoxicity Screening. DNA Damage from Benzo[a]pyrene Metabolites", Anal. Chem., 2007, 79, 1897-1906.
262. Sadagopan Krishnan, Eli G. Hvastkovs, Besnik Bajrami, Ingela Jansson, John B. Schenkman, and James F. Rusling, Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine. Chem. Commun., 2007, 1713 - 1715.
261. Sang-Nyon Kim, James F. Rusling, Fotis Papadimitrakopolous, Carbon Nanotubes in Electronic and Electrochemical Detection of Biomolecules (invited review), Advanced Materials., 2007, 19, 3214-3228.
260. Minjeong So, Eli G. Hvastkovs, John B. Schenkman, and James F. Rusling, Electrochemiluminescent/Voltammetric Toxicity Screening Sensor using Enzyme-Generated DNA Damage, Biosensors and Bioelectronics, 2007, 23, 492¨C498.
259. James F. Rusling, Eli G. Hvastkovs, and John B. Schenkman, Toxicity screening using biosensors that measure DNA damage, Curr. Opin. Drug Disc. & Devel., 2007, 10, 67-73.
258. Peterson M. Guto, Challa V. Kumar, and James F. Rusling, Thermostable Poly(lysine)-Enzyme Films for Biocatalysis at 90 oC , J. Phys. Chem. B  2007, 111, 9125-9131.
257. Sadagopan Krishnan and James F. Rusling, Thin film voltammetry of metabolic enzymes in rat liver microsomes, Electrochem. Commun., 2007, 9, 2359¨C2363.
256. Nasreen Sultana,  John B. Schenkman, and James F. Rusling, Direct Electrochemistry of Cytochrome P450 Reductases in Surfactant and Polyion Films, Electroanalysis, 2007, 19, 2499-2506
255. Erwin Fundador and James F. Rusling, Sensitive Detection of Labeled Abasic Sites in Damaged DNA by Capillary Electrophoresis with Laser Induced Fluorescence, Anal. Bioanal. Chem., 2007, 387, 1883¨C1890.
254. Book: "Encyclopedia of Electrochemistry", Volume 10: "Modified Electrodes" edited by Masamichi Fujihira, James F. Rusling and Israel Rubinstein, Wiley-VCH,  2007.
253. Steven L. Suib, Naifei Hu, and James F. Rusling, "Inorganic and Composite Films." In "Encyclopedia of Electrochemistry", In Volume 10: "Modified Electrodes" edited  by Masamichi Fujihira, James F. Rusling and Israel Rubinstein Wiley-VCH, 2007, pp. 375-384.
252. Merlin Bruening and James F. Rusling, ¡°Synthesis of Layered Polyelectrolyte Films¡± for "Encyclopedia of Electrochemistry", In Volume 10: "Modified Electrodes" edited by Masamichi Fujihira, James F. Rusling and Israel Rubinstein Wiley-VCH, 2007, pp. 386-396.

¡¾ÁªÏµµØÖ·¡¿
James F. Rusling
Department of Chemistry, U-3060
55 N. Eagleville Rd.
University of Connecticut
Storrs, Connecticut 06269-3060
United States

Phone: (860) 486-4909
Fax     : (860) 486-2981

E-mail: James.Rusling@uconn.edu

Websites:  http://www.sp.uconn.edu/~rusling
                   http://www.lib.uconn.edu/chemistry
33Â¥2008-01-19 20:03:26
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¡¾µ¼Ê¦ÐÕÃû¡¿Gary Siuzdak
¡¾Ñо¿·½Ïò¡¿   

    *  Mass analysis of intact viruses
    * Preparative MS with Electrospray
    * Mass-based inhibitor-enzyme screen
    * Observation of viral capsid dynamics
    * Desorption/Ionization on Silicon (DIOS)
    * XCMS: a nonlinear approach to align LC/MS data
    * Nanostructure Initiated Mass Spectrometry (NIMS)


¡¾ËùÔÚµ¥Î»¡¿Scripps center for mass spectrometry
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142           Northen T.R., Lee J-C, Hoang L., Raymond J., Hwang D-R, Yannone S.M., Wong C-H, Siuzdak G.
A Nanostructure-Initiator Mass Spectrometry Based Enzyme Activity Assay
PNAS, in press, 2007, ,      

141         Northen T.R., Nordstrom A., Yanes O., Siuzdak G.
Nanostructure-Initiator Mass Spectrometry
patent application, 2007, ,      

140         Nordstrom A. Want E., Northen T., Lehtio J., Siuzdak G.
Multiple Ionization Mass Spectrometry Strategy Reveals the Complexity of Metabolomics
Analytical Chemistry, 2008, 80, 421-429      PDF File

139         Northen T.R., Yanes O., Northen M.T., Marrinucci D., Uritboonthai W., Apon J., Golledge S.L., Nordstrom A., Siuzdak G.
Clathrate Nanostructures for Mass Spectrometry
Nature, 2007, 449, 1033-1036      

138         Wikoff W.R., Gangoitti J.A., Barshop B.A., Siuzdak G.
Metabolomics Identifies Novel Perturbations in Human Disorders of Propionate Metabolism
Clinical Chemistry, 2007, 53, 2169-2176      

137         Yanes O., Northen T.R., Uritboonthai W., Estrada M.N., Manchester M., Siuzdak G.
Nanostructure Initiator Mass Spectrometry for Biological Tissue Imaging and Biofluid Analysis
, submitted, 2007, ,      

136         Trauger S.A., Kalisiak E., Kalisiak J., Morita H., Weinbergb M.V., Menon A.L., Poole F.L. II, Adams M.W.W., Siuzdak G.
Correlating the Transcriptome, Proteome and Metabolome in the Environmental Adaptation of a Hyperthermophile
Journal of Proteome Research, in press, 2007, ,      

135         Nordstrom A., He L., Siuzdak G.
Desorption/Ionization on Silicon (DIOS)
Encyclopedia of Mass Spectrometry, Editor Michael Gross, 2007, 6, 676-683      PDF File

134         Go E.P., Uritboonthai W., Apon J.A., Trauger S.A., Nordstrom A., O'Maille G., Brittain S., Peters E.C., Siuzdak G.
Selective Metabolite and Peptide Capture/Mass Detection Using Fluorous Affinity Tags
Journal of Proteome Research, 2007, 6, 1492-1499      PDF File

133         Cohen L., Go E.P. , Siuzdak G.
Small Molecule Desorption/Ionization Mass Analysis
MALDI-MS Franz Hillenkamp - editor, 2007, IX, 299      PDF File

132         O'Maille G., Hoang L., Nordstrom A., Go E.P., Qin C., Siuzdak G.
Enhanced Metabolite Profiling via Chemical Derivatization and Isotope Labeling: An Application to Sepsis Prediction
submitted, 2007, ,      

131         Northen T.R., Woo H.K., Northen M.T., Nordstrom A., Uritboonthai W., Turner K., Siuzdak G.
High Surface Energy of Porous Silicon Drives Desorption of Intact Biomolecules
Journal of the American Society for Mass Spectrometry, 2007, 18(11),      PDF File

130         Pendyala G., Want E.J., Webb W., Siuzdak G., Fox H.S.
Biomarkers for NeuroAIDS: The widening scope of Metabolomics
Journal of NeuroImmune Pharmacology, 2007, 2, 72-80      PDF File

129         Want E.J., Nordstrom A., Morita H., Siuzdak G.
From Exogenous to Endogenous: The Inevitable Imprint of Mass Spectrometry in Metabolomics
Journal of Proteome Research, 2007, 6(2), 459-468      PDF File

128         Eraly S.A., Volker V., Rieg T., Gangioti J.A., Wu W., Barshop B.A., Siuzdak G., Wikoff W.R., Nigam S.K.
Loss of RST, the murine ortholog of the human urate transporter, URAT1, does not significantly alter renal excretion of urate
submitted, 2007, ,      

127         Mutch D.M., O'Maille G., Wikoff W., Wiedmer T., Sims P.J., Siuzdak G.
Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice
Genome Biology, 2007, 8, R38      PDF File

126         Chace D.H., Barr J.R., Duncan M.W., Matern D., Morris M.R., Palmer-Toy D.E., Rockwood A.L., Siuzdak G., Urbani A., Yergey A.L., Chan Y.M.
Mass Spectrometry in the Clinical Laboratory: General Principles and Guidance
Clinical and Laboratory Standards Institute, 2007, 27, 1-91      

125         Lissauer M., Johnson S.B., Siuzdak G., Bochicchio G., Whiteford C., Nussbaumer W., Moore R., Scalea T.S.
Coagulation and Complement Protein Differences Between Septic and Uninfected SIRS Patients
The Journal of Trauma, Injury, Infection and Critical Care, 2007, 62(5), 1080-1094      PDF File

¡¾ÁªÏµµØÖ·¡¿siuzdak@scripps.edu
34Â¥2008-01-20 22:38:13
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½ð³æ (Ö°Òµ×÷¼Ò)

¡¾µ¼Ê¦ÐÕÃû¡¿Werner Kuhr
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Capillary DNA Sequencing  

Electrochemical  DNA Methods  

Molecular Memory Arrays  

Micron Neuro-sensors  

CE-EC Microchip  

Multiplex Biomolecule Microfluidic EC  

¡¾ËùÔÚµ¥Î»¡¿UC Riverside
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ANALYTICAL CHEMISTRY 75 (14): 3301-3307 JUL 15 2003
ANALYTICAL CHEMISTRY 74 (14): 3421-3428 JUL 15 2002
ANALYTICAL CHEMISTRY 73 (20): 4882-4890 OCT 15 2001
LAB ON A CHIP 3 (2): 93-99 2003
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125 (2): 505-517 JAN 15 2003

¡¾ÁªÏµµØÖ·¡¿werner.kuhr@ucr.edu  
http://www.chem.ucr.edu/groups/k ... kuhr_background.htm
35Â¥2008-01-24 19:06:53
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½ð³æ (Ö°Òµ×÷¼Ò)

¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
wingcat(½ð±Ò+10,VIP+0):ллÌṩÐÅÏ¢£¬ÓëÂ¥ÉÏÐÅÏ¢Ò»²¢½±Àø~~~
¡¾µ¼Ê¦ÐÕÃû¡¿G. W. Whitesides
¡¾Ñо¿·½Ïò¡¿´ËÈËÊôÓÚ³¬¼¶´óÅ££¬Éæ×ãÁìÓò¼«¹ã£¬Óë·ÖÎöÏà¹ØµÄ·½ÏòÊÇMicrofluidics
¡¾ËùÔÚµ¥Î»¡¿Harvard
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Microfluidics
The Whitesides Group is very active in microfluidics. Our previous accomplishments in the field include work on laminar flow in microchannels (Figures 1,2), fabrication of three-dimensional channel topologies (Figures 3) and mixing by chaotic advection (Figure 4). We have also applied microfluidics to fabricate monodisperse polymer, hydrogel, and metal microparticles coated with thin, nylon-coated membranes (Figure 5). Currently, we are working on several projects related to microfluidics, including exploiting the behavior of bubbles and droplets for mixing and other applications, manipulating samples electrokinetically and probing the use of solder as electrodes in microchannels.



Bubbles and Droplets in Microchannels

Our recent experiments in microfluidics include investigations into the behavior of bubbles and droplets in microchannels. Specifically, we are interested in four sub-areas: (1) enhanced mixing in microfluidic systems using bubbles; (2) the paths from monodisperse to chaotic bubbling in flow-focusing devices; (3) the production of bubbles with uniquely high periodicities in modified flow-focusing systems; (4) the path-selection process that bubbles demonstrate as they move through a network. Mixing in microchannels, in particular, is an important challenge in the microfluidics subgroup of our laboratory (the other areas introduced here are described further in the complexity section of the website).

Mixing between streams of fluid that flow in a laminar fashion is difficult to achieve. Previously, we have introduced a method to enhance mixing involving multiple lithographic steps. Our current work uses bubbles to facilitate the folding over of streams of fluid as they proceed through a network of microchannels (Movie 6). The bubbles partially block the channels in which they move, causing a portion of a stream of bulk fluid to cross over into the channel in which the other stream moves. This process is repeated several times before the streams are mixed fully, with the final mixing device occupying an area of only a square millimeter on the chip.



Electrokinetic Flow in Microfluidic Channels

We are exploring electrokinetically-driven microfluidic systems for separation of complex biological samples. Our ultimate goal is to provide a new sample handling method (femtomole/nL) for proteomic analysis and high-throughput biochemical assays. Currently, we are investigating geometrical designs, surface coatings and concentration techniques such as isotachophoresis.



TWIST Valves

We have developed a new approach for controlling the flow of fluids in microfluidic channels. TWIST valves consist of small machine screws (500 um diameter) embedded in a layer of polyurethane cast above microfluidic channels fabricated in poly(dimethylsiloxane) (PDMS). The polyurethane is cured photochemically with the screws in place; on curing, it bonds to the surrounding layer of PDMS and forms a stiff layer that retains an impression of the threads of the screws (Figure 7). The valves are separated from the ceiling of microfluidic channels by a layer of PDMS, and are integrated into channels using a simple procedure compatible with rapid prototyping. Turning the screws actuates the valves by collapsing the PDMS layer between the valve and channel, controlling the flow of fluids in the underlying channels. These valves have the useful characteristic that they do not require power to retain their setting (on/off). They also allow settings between "on" and "off", resist large back pressures (>350 kPa) without failure, and can be integrated into portable, disposable microfluidic devices for carrying out biological assays (Figure 8).



TWIST Pumps

We have designed a system for storing and pumping fluids in microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS) using TWIST valves. The method uses valves to isolate microfluidic reservoirs that are filled with solutions of reagents under pressure; the fluid is released, and the flow rate controlled, by opening one of the valves. Figure 9 shows a microfluidic pump fabricated using this approach.



References

1. Jeon, N. L. et al. "Generation of Solution and Surface Gradients Using Microfluidic Systems", Langmuir, 2000, 16, 8311-8316.

2. Wu, H. et al. "Fabrication of Topologically Complex Three-Dimensional Microstructures: Metallic Microknots" J. Am. Chem. Soc., 2001, 122, 12691-12699.

3. Stroock, A. D. et al. "Chaotic Mixer for Microchannels" Science, 2002, 295, 647-654.

4. Xu, S. et al "Generation of Monodisperse Particles by Using Microfluidics: Control over Size, Shape, and Composition" Angewandte Chemie 44 (5), 2005, 724-728.

5. Weibel, D. B. et al. "Torque-Actuated Valves for Microfluidics" Analytical Chemistry 77(15); 4726-4733, 2005.

¡¾ÁªÏµµØÖ·¡¿gwwhitesides@gmwgroup.harvard.edu
http://gmwgroup.harvard.edu/
http://gmwgroup.harvard.edu/contact.html
36Â¥2008-01-24 19:12:06
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chenwenlong

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¡¾µ¼Ê¦ÐÕÃû¡¿M.D. Luque de Castro
¡¾Ñо¿·½Ïò¡¿ÑùƷǰ´¦Àí¼¼Êõ
¡¾ËùÔÚµ¥Î»¡¿Department of Analytical Chemistry, Annex Marie Curie Building, Campus of Rabanales,
University of C¨®rdoba, E-14071 C¨®rdoba, Spain
¡¾Ñо¿³É¹û¡¿
1.Simultaneous Ultrasound-Assisted Emulsification-Extraction of Polar and Nonpolar Compounds from Solid Plant Samples
Perez-Serradilla, J. A.; Priego-Capote, F.; Luque de Castro, M. D.
Anal. Chem.; (Article); 2007; 79(17); 6767-6774.

2.Continuous Ultrasound-Assisted Extraction Coupled to Flow Injection-Pervaporation, Derivatization, and Spectrophotometric Detection for the Determination of Ammonia in Cigarettes
Caballo-Lopez, A.; Luque deCastro, M. D.
Anal. Chem.; (Article); 2006; 78(7); 2297-2301.

3.Slurry Sampling-Microwave Assisted Leaching Prior to Hydride Generation-Pervaporation-Atomic Fluorescence Detection for the Determination of Extractable Arsenic in Soil
Caballo-Lopez, A.; Luque de Castro, M. D.
Anal. Chem.; (Article); 2003; 75(9); 2011-2017

4.Pressurized Hot Water Extraction with On-Line Fluorescence Monitoring: a Comparison of the Static, Dynamic, and Static-Dynamic Modes for the Removal of Polycyclic Aromatic Hydrocarbons from Environmental Solid Samples
Morales-Munoz, S.; Luque-Garcia, J. L.; Luque de Castro, M. D.
Anal. Chem.; (Article); 2002; 74(16); 4213-4219.

5.Water Soxhlet Extraction Assisted by Focused Microwaves: A Clean Approach
Luque-Garcia, J. L.; Luque de Castro, M. D.
Anal. Chem.; (Article); 2001; 73(24); 5903-5908.  

6.Approach for Independent-Matrix Removal of Polycyclic Aromatic Hydrocarbons from Solid Samples Based on Microwave-Assisted Soxhlet Extraction with On-Line Fluorescence Monitoring
Garcia-Ayuso, L. E.; Luque-Garcia, J. L.; Luque de Castro, M. D.
Anal. Chem.; (Article); 2000; 72(15); 3627-3634.

7.Focused Microwave-Assisted Soxhlet: An Advantageous Tool for Sample Extraction
Garcia-Ayuso, L. E.; Sanchez, M.; Fernandez de Alba, A.; Luque de Castro, M. D.
Anal. Chem.; (Technical Note); 1998; 70(11); 2426-2431.

8.Reverse Micelle Formation for Acceleration of the Supercritical Fluid Extraction of Cholesterol from Food Samples
Jimenez-Carmona, M. M.; Luque de Castro, M. D.
Anal. Chem.; (Article); 1998; 70(10); 2100-2103.

9.Pervaporation as an Alternative to Headspace
Bryce, D. W.; Izquierdo, A.; Luque de Castro, M. D.
Anal. Chem.; (Article); 1997; 69(5); 844-847.  

10.Integrated Pervaporation/Detection: Continuous and Discontinuous Approaches for Treatment/Determination of Fluoride in Liquid and Solid Samples
I. Papaefstathiou, M. D. Luque de Castro
Anal. Chem.; 1995; 67(21); 3916-3921
Online Coupling of a Flow-Through Sensor to a Supercritical Fluid Extractor
M. T. Tena, M. D. Luque de Castro, M. Valcarcel
Anal. Chem.; 1995; 67(6); 1054-1059.

12.Phase Discrimination in Continuous Liquid-Liquid Extraction with Diode Array Photometric Detection
F. Ortiz-Boyer, J. A. Garcia-Mesa, M. D. Luque de Castro
Anal. Chem.; 1994; 66(17); 2794-2798.

13.Flow-through optical biosensor based on the permanent immobilization of an enzyme and transient retention of a reaction product
J. M. Fernandez-Romero, M. D. Luque de Castro
Anal. Chem.; 1993; 65(21); 3048-3052.

14.Flow-through sensor for the direct determination of pesticide mixtures without chromatographic separation
B. Fernandez-Band, P. Linares, M. D. Luque de Castro, M. Valcarcel
Anal. Chem.; 1991; 63(17); 1672-1675

15.Analytical potential of flow-reversal injection analysis
Angel Rios, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1988; 60(15); 1540-1545

16.Individual and simultaneous determination of ethanol and acetaldehyde in wines by flow injection analysis and immobilized enzymes
Fernando Lazaro, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1987; 59(14); 1859-1863

17.Doubly stopped flow: a new alternative to simultaneous kinetic multideterminations in unsegmented flow systems
Fernando Lazaro, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1987; 59(7); 950-954.
Electrochemical determination of sulfur dioxide in air samples in closed-loop flow injection system
Angel Rios, M. D. Luque de Castro, Miguel Valcarcel, Horacio A. Mottola
Anal. Chem.; 1987; 59(4); 666-670.

19.Simultaneous determination of pyridoxal and pyridoxal 5-phosphate in human serum by flow injection analysis
Pilar Linares, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1985; 57(11); 2101-2106.

20.Multidetection in unsegmented flow systems with a single detector
Angel Rios, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1985; 57(9); 1803-1809.

21.Comparison of flow injection analysis configurations for differential kinetic determination of cobalt and nickel
Alfonso Fernandez, M. D. Luque de Castro, Miguel Valcarcel
Anal. Chem.; 1984; 56(7); 1146-1151.

¡¾ÁªÏµµØÖ·¡¿Tel./Fax: +34 957 218 615;
E-mail: QA1LUCAM@UCO.ES
37Â¥2008-01-25 14:32:49
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R. Graham Cooks

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¡¾µ¼Ê¦ÐÕÃû¡¿R. Graham Cooks

http://aston.chem.purdue.edu/welcome

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R. Graham Cooks½ÌÊÚÓÚ1966Äê»ñµÃNatal´óѧÕÜѧ²©Ê¿Ñ§Î»£¬1967Äê»ñÓ¢¹ú½£ÇÅ´óѧ²©Ê¿Ñ§Î»¡£ÏÖÈÎÃÀ¹úÆÕ¶É´óѧ½ÌÊÚ¡£Ö÷ÒªÑо¿·½ÏòΪÖÊÆ×ѧ¡£1985Äê±»ÊÚÓèÖÊÆ×ѧÁìÓòµÄ×î¸ßÈÙÓþThomson½±¡£ÒòΪËûÔÚÀë×ÓÚå´®ÁªÖÊÆ×ÁìÓòµÄ½Ü³ö¹±Ï×£¬2002Äê»ñŵ±´¶û»¯Ñ§½±ÌáÃû¡£R. Graham Cooks½ÌÊÚͬʱ»¹ÊÇÆÕ¶É´óѧHenry Bohn Hass½Ü³ö½ÌÊÚ£¬¹ú¼ÊÖÊÆ×ѧ»áÖ÷ϯ£¬ÖйúÖÊÆ×ѧ»áÈÙÓþ»áÔ±£¬²¢±»¹ú¼ÊÉ϶àËù´óѧºÍÑо¿»ú¹¹Æ¸ÇëΪÈÙÓþ½ÌÊÚ¡£
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Analytical Chemistry  2007  79  - 89-97  
Analytical Chemistry  2006  78  - 8549-8555  
Analytical Chemistry  2006  78  - 718-725  
Analytical Chemistry  2007  79  - 6398-6403

International Journal of Mass Spectromet 2007  259  - 8-15  

Journal of Mass Spectrometry  2007  42  - 1086-1092  
Journal of Mass Spectrometry  2007  42  - 675-680  

Journal of the American Chemical Society 2007  129  - 5880-5886  

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Email: cooks@purdue.edu
Phone: 765-494-5263
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ëϸ¹ÜµçÓ¾ºÍÀë×ÓÉ«Æ×ר¼ÒCharles A. Lucy

Charles A. Lucy
Professor
B.Sc., University of Victoria
Ph.D., University of Alberta

Office: W3-55, Chemistry Centre
Phone: (780) 492-0315
E-mail: charles.lucy@ualberta.ca

Group Web Page:
http://www.chem.ualberta.ca/~chaslucy/

Dr. Lucy¡¯s research is in the area of analytical separations. The major objective of the research is to develop a fundamental physico-chemical understanding of high performance liquid chromatography (HPLC), ion chromatography (IC) and capillary electrophoresis (CE). This fundamental understanding is then coupled with collaborations with instrument manufacturers such as Dionex and Perkin Elmer and industrial partners such as Dow Chemicals and Syncrude Canada Ltd. to enhance and even simplify the analytical methods.

Examples of recent research by undergraduate and graduate students in the lab are the development of:

a fundamental understanding of electrophoretic mobility;
self-assembled coatings based on supported phospholipid bilayers for protein separations using capillary electrophoresis;
fluorescence detectors capable of pico-molar (10-12 M) detection limits based on diode lasers and light emitting diodes;
ion chromatography methods that are 20-times faster than conventional methods;
high temperature normal phase HPLC for petroleum analysis.
Students have received awards from NSERC, Alberta Ingenuity, the American Chemical Society, the Canadian Society of Chemistry and the University of Alberta. Past students found employment in academia, the pharmaceutical and petroleum industries and government labs.

Selected Publications

Kimberly I. Roy and Charles A. Lucy, "Capillary Electrophoresis in aqueous-organic media: Ionic Strength Effects and Limitations of the Hubbard-Onsager Dielectric Friction Model", Journal of Chromatography A 2003, 964, 213-225.

Chuanzhong Wang and Charles A. Lucy, ¡°Oligomerized phospholipid bilayers as coatings in capillary zone electrophoresis¡±, Analytical Chemistry 2005, 77, 2015-2021.

Ebbing P. de Jong and Charles A. Lucy, ¡°Low-picomolar limits of detection using high-power light-emitting diodes for fluorescence¡±, Analyst, 2006, 131, 664-669.

Panos Hatsis and Charles A. Lucy, "High-Speed Ion Chromatography With Monolithic Stationary Phases and Suppressed Conductivity Detection", Analytical Chemistry 2003, 75, 995-1001.

Richard E. Paproski, Jean Cooley and Charles A. Lucy, ¡°Fast supercritical fluid chromatography hydrocarbon group-type separations of diesel fuels using packed and monolithic columns¡±, Analyst 2006, 131, 422-428.

C.A. LucyÔÚëϸ¹ÜµçÓ¾µ°°×ÖÊ·ÖÀë·½Ãæ×ö³öÁ˸»Óгɾ͵Ť×÷£¬Í¬Ê±ÔÚ¸ßЧҺÏàÉ«Æ×ºÍÀë×ÓÉ«Æ×·½ÃæÒ²¸»Óй±Ï×
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39Â¥2008-02-04 21:56:08
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½ºÊøµç¶¯É«Æ×µÄ·¢Ã÷ÈËShigeru Terabe

ÈÕ±¾¼§Â·¹¤Òµ´óѧ²ÄÁÏ¿ÆÑ§Ïµ£ºShigeru Terabe½ÌÊÚ (É«Æ×·ÖÎö)

¡¾URL¡¿ http://www.sci.u-hyogo.ac.jp/mat ... be-lab/index-e.html

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     Professor
Shigeru TERABE, D. Engn.
Email: terabe@sci.himeji-tech.ac.jp

Faculty of Science
Himeji Institute of Technology
Kamigori, Hyogo 678-1297, Japan
Phone: +81-791-58-0172
FAX: +81-791-58-0493

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