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Yinsheng Wang@UCR
★ ★ ★ ★
yensh(金币+4,VIP+0):谢谢分享，节日快乐
【导师姓名】Yinsheng Wang
【研究方向】Oxidative DNA Damage；Post-translational Modifications of HMG Proteins
【所在单位】Department of Chemistry
University of California at Riverside
Labs: Physical Sciences I, 339, 341, 343, 345, 347
Lab Phone Numbers: (951)827-2593, 2701
【研究成果】Publications
2007
Zhang, Q. and Wang, Y.* Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity. J. Proteome Res., 2007, 6, in press.
Hong, H.; Cao, H. and Wang, Y.* Formation and genotoxicity of a guanine-cytosine intrastrand cross-link lesion in vivo. Nucleic Acids Res., 2007, 35, in press.
Jiang, Y.; Hong, H.; Cao, H. and Wang, Y.* In-vivo formation and in-vitro replication of a guanine-thymine intrastrand cross-link lesion. Biochemistry, 2007, 46, in press.
Gao, Y. and Wang, Y.* A method to determine the ionization efficiency change of peptides caused by phosphorylation. J. Am. Soc. Mass Spectrom., 2007, 19, in press.
Cao, H.; Jiang, Y. and Wang, Y.* Stereospecific synthesis and characterizations of oligodeoxyribonucleotides containing N2-(1-carboxyethyl)-2’-deoxyguanosine. J. Am. Chem. Soc, 2007, 129, 12123-12130.
Zhang, Q.; Zhang, K.; Zou, Y.; Perna, A. D. and Wang, Y.* A quantitative study on the in-vitro and in-vivo acetylation of high mobility group A1 proteins. J. Am. Soc. Mass Spectrom., 2007, 19, 1569-1578.
Cao, H. and Wang, Y.* Quantification of oxidative single-base and intrastrand cross-link lesions in unmethylated and CpG-methylated DNA induced by Fenton-type reagents. Nucleic Acids Res., 2007, 35, 4833-4844.
Men, L. and Wang, Y.* The oxidation of yeast alcohol dehydrogenase-1 by hydrogen peroxide in vitro. J. Proteome Res., 2007, 6, 216-225.
Hong, H. and Wang, Y.* Derivatization with Girard reagent T combined with LC-MS/MS for the sensitive detection of 5-formyl-2’-deoxyuridine in cellular DNA. Anal. Chem., 2007, 79, 322-326.
Zou, Y.; Wang, Y.* Mass spectrometric analysis of high-mobility group proteins and their post-translational modifications in normal and cancerous human breast tissues. J. Proteome Res. 2007, 6, 2304-2314.
Gu, C.; Wang, Y.* In-vitro replication and thermodynamic studies of methylation and oxidation modifications of 6-thioguanine. Nucleic Acids Res., 2007, 35, 3693-3704.
Zou, Y.; Webb, K.; Perna, A. D.; Zhang, Q.; Clarke, S.; and Wang, Y.* A mass spectrometric study on the in-vitro methylation of HMGA1a and HMGA1b proteins by PRMTs: methylation specificity, the effect of binding to AT-rich duplex DNA and the effect of C-terminal phosphorylation. Biochemistry, 2007, 46, 7896-7906.
Zeng, Y. and Wang, Y.* UVB-induced formation of intrastrand crosslink products of DNA in MCF-7 cells treated with 5-bromo-2’-deoxyuridine. Biochemistry, 2007, 46, 8189-8195.
Qiu, H. and Wang, Y.* Probing adenosine nucleotide-binding proteins with an affinity labeled-nucleotide probe and mass spectrometry. Anal. Chem., 2007, 79, 5547-5556.
Jiang, D; Men, L.; Wang, J.; Zhang, Y; Chickenyen, S.; Wang, Y. and Zhou, F.* Redox reactions of copper complexes formed with different b-amyloid peptides and their neuropathalogical relevance. Biochemistry, 2007, 46, 9270-9282.
Men, L.; Roginskaya, M.; Zou, Y. and Wang, Y.* Redox-dependent formation of disulfide bonds in human replication protein A. Rapid Commun. Mass Spectrom., 2007, 21, 2743-2749.
2006
Men, L. and Wang, Y.* Fragmentation of the deprotonated ions of peptides containing cysteine, cysteine sulfinic acid, cysteine sulfonic acid, aspartic acid, and glutamic acid. Rapid Commun. Mass Spectrom., 2006, 20, 777-784.
Hong, H.; Cao, H.; Wang, Y. and Wang, Y.* Identification and quantification of a guanine-thymine intrastrand crosslink lesion induced by Cu(II)/H2O2/ascorbate. Chem. Res. Toxicol., 2006, 19, 614-621.
Zeng, Y. and Wang, Y.* Facile photocyclization chemistry of 5-Phenylthio-2’-deoxyuridine in duplex DNA. Org. Lett., 2006, 8, 2527-2530.
Zhang, Q. and Wang, Y.* Differentiation of 2’-O- and 3’-O-methylated ribonucleosides by tandem mass spectrometry. J. Am. Soc. Mass Spectrom., 2006, 17, 1096-1099.
Jiang, X. and Wang, Y.* Phosphorylation of human high mobility group N1 protein by protein kinase CK2. Biochem. Biophys. Res. Commun., 2006, 345, 1497-1503.
Jiang, X. and Wang, Y.* Acetylation and phosphorylation of high-mobility group A1 proteins in PC-3 human tumor cells. Biochemistry, 2006, 45, 7194-7201.
Wang, Y. and Wang, Y.* Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2’-deoxyguanosine. Chem. Res. Toxicol., 2006, 19, 837-843.
Cao, H. and Wang, Y.* Collisionally activated dissociation of protonated 2’-deoxycytidine, 2’-deoxyuridine and their oxidatively damaged derivatives. J. Am. Soc. Mass Spectrom., 2006, 17, 1335-1341.
Gu, C.; Zhang, Q.; Yang, Z.; Wang, Y.; Zou, Y. and Wang, Y.* Recognition and incision of oxidative intrastrand cross-link lesions by UvrABC nuclease. Biochemistry, 2006, 45, 10739-46.
Zeng, Y. and Wang, Y.* Sequence-dependent formation of intrastrand crosslink products from the UVB irradiation of duplex DNA containing a 5-bromo-2’-deoxyuridine or 5-bromo-2’-deoxycytidine. Nucleic Acids Res., 2006, 34, 6521-6529.
Sun, W.; Lee, T. S.; Zhu, M.; Gu, C.; Wang, Y., Zhu, Y., and Shyy, J. Y.* Statins activate AMP-activated protein kinase in vitro and in vivo. Circulation, 2006, 114, 2655-2662.
Gao, Y. and Wang, Y.* Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal. Biochemistry, 2006, 45, 15654-15660.
【联系地址】yinsheng.wang@ucr.edu |
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