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yensh

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padodo

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毛细管电泳和离子色谱专家Charles A. Lucy

Charles A. Lucy
Professor
B.Sc., University of Victoria
Ph.D., University of Alberta

Office: W3-55, Chemistry Centre
Phone: (780) 492-0315
E-mail: charles.lucy@ualberta.ca

Group Web Page:
http://www.chem.ualberta.ca/~chaslucy/

Dr. Lucy’s research is in the area of analytical separations. The major objective of the research is to develop a fundamental physico-chemical understanding of high performance liquid chromatography (HPLC), ion chromatography (IC) and capillary electrophoresis (CE). This fundamental understanding is then coupled with collaborations with instrument manufacturers such as Dionex and Perkin Elmer and industrial partners such as Dow Chemicals and Syncrude Canada Ltd. to enhance and even simplify the analytical methods.

Examples of recent research by undergraduate and graduate students in the lab are the development of:

a fundamental understanding of electrophoretic mobility;
self-assembled coatings based on supported phospholipid bilayers for protein separations using capillary electrophoresis;
fluorescence detectors capable of pico-molar (10-12 M) detection limits based on diode lasers and light emitting diodes;
ion chromatography methods that are 20-times faster than conventional methods;
high temperature normal phase HPLC for petroleum analysis.
Students have received awards from NSERC, Alberta Ingenuity, the American Chemical Society, the Canadian Society of Chemistry and the University of Alberta. Past students found employment in academia, the pharmaceutical and petroleum industries and government labs.

Selected Publications

Kimberly I. Roy and Charles A. Lucy, "Capillary Electrophoresis in aqueous-organic media: Ionic Strength Effects and Limitations of the Hubbard-Onsager Dielectric Friction Model", Journal of Chromatography A 2003, 964, 213-225.

Chuanzhong Wang and Charles A. Lucy, “Oligomerized phospholipid bilayers as coatings in capillary zone electrophoresis”, Analytical Chemistry 2005, 77, 2015-2021.

Ebbing P. de Jong and Charles A. Lucy, “Low-picomolar limits of detection using high-power light-emitting diodes for fluorescence”, Analyst, 2006, 131, 664-669.

Panos Hatsis and Charles A. Lucy, "High-Speed Ion Chromatography With Monolithic Stationary Phases and Suppressed Conductivity Detection", Analytical Chemistry 2003, 75, 995-1001.

Richard E. Paproski, Jean Cooley and Charles A. Lucy, “Fast supercritical fluid chromatography hydrocarbon group-type separations of diesel fuels using packed and monolithic columns”, Analyst 2006, 131, 422-428.

C.A. Lucy在毛细管电泳蛋白质分离方面做出了富有成就的工作，同时在高效液相色谱和离子色谱方面也富有贡献