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zhongyujiao金虫 (小有名气)
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[求助]
请大家帮忙在SCI上检索一下这两篇文章，看能不能找到
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PREPARATION AND CHARACTERIZATION OF GLYCYRRHETINIC ACID-MODIFIED POLOXAMER 188/CHITOSAN NANOPARTICLES 和 Two new naphthoquinone derivatives from Lysionotus pauciflorus. |
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baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
- 应助: 4642 (副教授)
- 贵宾: 46.969
- 金币: 658104
- 散金: 11616
- 红花: 995
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- 帖子: 69424
- 在线: 13328.4小时
- 虫号: 676696
- 注册: 2008-12-18
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- 专业: 合成药物化学
- 管辖: 有机交流
【答案】应助回帖
★ ★
yaolan123: 金币+2, 感谢应助，奖励一下 2013-11-08 14:08:10
jssxh: 检索EPI+1, 谢谢参与，请继续关注本版块！ 2013-12-16 09:21:53
yaolan123: 金币+2, 感谢应助，奖励一下 2013-11-08 14:08:10
jssxh: 检索EPI+1, 谢谢参与，请继续关注本版块！ 2013-12-16 09:21:53
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1. http://apps.webofknowledge.com/f ... age=1&doc=1 PREPARATION AND CHARACTERIZATION OF GLYCYRRHETINIC ACID-MODIFIED POLOXAMER 188/CHITOSAN NANOPARTICLES 作者: Wang, J (Wang, Jing)[ 1 ] ; Guo, L (Guo, Li)[ 2 ] ; Ma, LF (Ma, Li Fang)[ 1 ] 来源出版物: NANO 卷:8 期:4 文献号:1350042 DOI:10.1142/S1793292013500422 出版年:AUG 2013 被引频次: 0 (来自 Web of Science) 引用的参考文献: 12 [ 查看 Related Records ] 引证关系图 摘要: In this paper, we firstly synthesized glycyrrhetinic acid-modified double amino-terminated poloxamer 188 (GA-NH-POLO-NH-GA). The structure of the synthesized compound was confirmed by 1 H-NMR and Fourier transform infrared (FT-IR) spectroscopy. Then the nano-particles composed of GA-NH-POLO-NH-GA/chitosan (GA-NH-POLO-NH-GA/CTS) were prepared by an ionic gelation process. The characterization of the nanoparticles was measured by dynamic light scattering (DLS) and scanning electron microscope (SEM). The results showed that the nanoparticles were well dispersed with a spherical shape and the particle size was distributed between 100 nm and 300 nm. The cytotoxicity based on MTT assay against cells (QGY-7703 cells and L929 cells) showed that the nanoparticles had low toxicity and good biocompatibility. The encapsulation efficiency and drug loading of 5-fluorouracil-loaded nanoparticles (5-FU nanoparticles) were measured by high-performance liquid chromatography (HPLC) and fluorescence spectroscopy, ultraviolet-visible (UV-vis) absorbance. The encapsulation of 5-Fu-loaded CTS nanoparticles was 12.8% and the drug loading was 2.9%, while the encapsulation of 5-Fu-loaded GA-NH-POLO-NH-GA/CTS nanoparticles was 20.9% and the drug loading was 3.36%. The release profile showed that the GA-NH-POLO-NH-GA/CTS nanoparticles were available for sustained release of 5-Fu. The GA-NH-POLO-NH-GA/CTS nanoparticles have a higher affinity to the QGY-7703 cells, so indicated that the GA-NH-POLO-NH-GA/CTS nanoparticles have the capacity of liver-targeting in vitro. 入藏号:WOS:000321954700009 文献类型: Article 语种: English 作者关键词: Glycyrrhetinic acid; poloxamer 188; chitosan; nanoparticles; sustained release; liver-targeting KeyWords Plus: CANCER-THERAPY; CHITOSAN 通讯作者地址: Ma, LF (通讯作者) Sichuan Univ, Dept Pharmaceut & Biol Engn, Chengdu 610065, Peoples R China. 地址: [ 1 ] Sichuan Univ, Dept Pharmaceut & Biol Engn, Chengdu 610065, Peoples R China [ 2 ] Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist, Dept Med Chem,West China Sch Pharm, Chengdu 610041, Peoples R China 电子邮件地址: wangjingrose3@163.com; rosaguoli2000@yahoo.com.cn; MLfang11@126.com 出版商:WORLD SCIENTIFIC PUBL CO PTE LTD, 5 TOH TUCK LINK, SINGAPORE 596224, SINGAPORE Web of Science 类别: Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied 研究方向: Science & Technology - Other Topics; Materials Science; Physics IDS 号:185GJ ISSN:1793-2920 |
2楼2013-11-08 10:48:13
baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
- 应助: 4642 (副教授)
- 贵宾: 46.969
- 金币: 658104
- 散金: 11616
- 红花: 995
- 沙发: 81
- 帖子: 69424
- 在线: 13328.4小时
- 虫号: 676696
- 注册: 2008-12-18
- 性别: GG
- 专业: 合成药物化学
- 管辖: 有机交流
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★
yaolan123: 金币+2, 感谢应助，奖励一下 2013-11-08 14:08:16
zhongyujiao(江南的竹代发): 金币+10 2014-03-06 20:49:20
yaolan123: 金币+2, 感谢应助，奖励一下 2013-11-08 14:08:16
zhongyujiao(江南的竹代发): 金币+10 2014-03-06 20:49:20
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2. 按照你给的标题未检索到，有个类似的不知是否是你需要的，你可自己检索下看看 http://apps.webofknowledge.com/f ... age=1&doc=1 Two New Naphthoquinone Derivatives from the Stem Bark of Callicarpa maingayi 作者: Asiri, SM (Asiri, Sumayah Mohammed)[ 1 ] ; Shaari, K (Shaari, Khozirah)[ 1,2 ] ; Abas, F (Abas, Faridah)[ 1,3 ] ; Al-Mekhlafi, NA (Al-Mekhlafi, Nabil Ali)[ 1 ] ; Lajis, NH (Lajis, Nordin H.)[ 1 ] 来源出版物: NATURAL PRODUCT COMMUNICATIONS 卷:7 期:10 页:1333-1336 出版年:OCT 2012 被引频次: 0 (来自 Web of Science) 引用的参考文献: 15 [ 查看 Related Records ] 引证关系图 摘要: Two new naphthoquinones designated as 3 alpha-hydroxy-2-(2-hydroxypropan-2-yl)-9 alpha-methoxy-2,3,3 alpha,9 alpha-tetra-hydronaphtho[2,3-b]furan-4,9-dione (callicarpaquinone A, 1) and 5-hydroxy-2-(2-hydroxypropan-2-yl)naphtho[2,3-b]furan-4,9-dione (callicarpaquinone B, 2) were isolated from the chloroform fraction of Callicarpa maingayi. Three other known compounds, identified as avicequinone-C (3), wodeshiol (4) and paulownin (5), were reported for the first time from this species. The structure elucidation of compounds was established by comprehensive 1D and 2D NMR spectroscopic analyses as well as EIMS, UV and IR spectral data. Compounds 1 and 2 were tested in vitro for their cytotoxic activity against human breast cancer MCF-7cells. Compound 2 exhibited strong cytotoxic activity with an IC50 value of 1.9 +/- 0.2 mu M, while 1 showed moderate activity with an IC50 value of 25.0 +/- 4.3 mu M. 入藏号:WOS:000310189200021 文献类型: Article |
3楼2013-11-08 10:51:54
