| 查看: 631 | 回复: 3 | ||
| 本帖产生 1 个 LS-EPI ，点击这里进行查看 | ||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | ||
[求助]
求助默克索引相关信息，谢谢大家
|
||
|
求助默克索引相关信息，谢谢大家，可追加金币： 英文通用名：Ixabepilone 中文通用名：伊沙匹隆 商品名： Ixempra CAS登录号：219989-84-1 |
回复此楼» 猜你喜欢
一志愿211 0703化学 346分求调剂
已经有26人回复
-
生物学调剂
已经有13人回复
-
293求调剂
已经有15人回复
-
335求调剂
已经有17人回复
-
人工智能320调剂08工类还有机会吗
已经有14人回复
-
271求调剂
已经有27人回复
-
考研求调剂
已经有7人回复
-
085408光电信息工程专硕355一志愿长春光机所调剂
已经有3人回复
-
071000生物学，一志愿深圳大学296分，求调剂
已经有15人回复
-
302求调剂
已经有7人回复
3楼2013-09-16 22:24:09
baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
- 应助: 4642 (副教授)
- 贵宾: 46.97
- 金币: 658713
- 散金: 11616
- 红花: 995
- 沙发: 81
- 帖子: 69434
- 在线: 13334.2小时
- 虫号: 676696
- 注册: 2008-12-18
- 性别: GG
- 专业: 合成药物化学
- 管辖: 有机交流
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★
哲凝: 金币+10, ★★★很有帮助, 谢谢 2013-09-16 22:22:52
jssxh: 金币+3, 检索EPI+1, 谢谢参与，请继续关注本版块！ 2014-03-05 11:48:12
哲凝: 金币+10, ★★★很有帮助, 谢谢 2013-09-16 22:22:52
jssxh: 金币+3, 检索EPI+1, 谢谢参与，请继续关注本版块！ 2014-03-05 11:48:12
|
Title: Ixabepilone CAS Registry Number: 219989-84-1 CAS Name: (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione Additional Names: azaepothilone B Manufacturers' Codes: BMS-247550; NSC-710428 Molecular Formula: C27H42N2O5S Molecular Weight: 506.70 Percent Composition: C 64.00%, H 8.35%, N 5.53%, O 15.79%, S 6.33% Literature References: Microtubule stabilizing semisynthetic lactam analog of epothilone B, q.v. Prepn: G. D. Vite et al., WO 9902514; eidem, US 6605599 (1999, 2003 both to Bristol-Myers Squibb); R. M. Borzilleri et al., J. Am. Chem. Soc. 122, 8890 (2000). Antineoplastic activity in vitro and in vivo: F. Y. F. Lee et al., Clin. Cancer Res. 7, 1429 (2001). Clinical evaluation with estramustine in prostate cancer: J. E. Rosenberg et al., Cancer 106, 58 (2006). Clinical pharmacokinetics and evaluation in solid tumors: S. Mani et al., Clin. Cancer Res. 10, 1289 (2004). Clinical evaluation in breast cancer: J. A. Low et al., J. Clin. Oncol. 23, 2726 (2005); in prostate cancer: M. Hussain et al., ibid. 8724. Review of pharmacology and clinical development: N. Lin et al., Curr. Opin. Invest. Drugs 4, 746-756 (2003). Properties: Colorless oil or white lyopholizate; [a]D22 -40.7° (c = 1.0 in chloroform). Optical Rotation: [a]D22 -40.7° (c = 1.0 in chloroform) Therap-Cat: Antineoplastic. Keywords: Antineoplastic; Alkaloids/Natural Products. |
2楼2013-09-16 22:05:41
4楼2014-03-04 15:04:27
