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【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ wgnydynl: 金币+30, 翻译EPI+1, ★有帮助 2013-04-28 14:00:17
A novel midchain-functional chain transfer agent was synthesized and used as a reversible addition-fragmentation chain transfer polymerization agent to prepare branched poly(N-(2-hydroxypropyl) methacrylamide) (PHPMA).
合成了一个新的中链-功能化链转移剂,并将其作为一种逆向加片段型链转移聚合剂来制备枝状PHPMA。
The P(HPMA) contained a thio-reactive group, namely, pyridyldisulfide midchain.
PHPMA有一个含硫活性基团,即吡啶基硫化物中链。
The synthesized polymers were fully analyzed by 1H NMR, GPC, and hydrolysis, confirming well-defined structures (predesigned molecular weights, narrow polydispersities, and high functionalization efficiencies).
用1H NMR、GPC和水解对合成的聚合物进行全面分析,证实其有良好的结构(预先设计的分子量、窄的多分散性、高能效)。
These midfunctionalized polymers were incubated with bovine serum albumin to generate protein-polymer conjugates.
将这个中功能化聚合物和牛血清白蛋白孵育,从而产生蛋白质-聚合物缀合体。
This straightforward methodology for the synthesis of branched midfunctionalized polymers for protein conjugation has the potential to enhance the properties of polymer-protein conjugates by improving biomolecule stability and enhancing circulation time.
这个用于合成枝状中功能化聚合物(用于制备蛋白质缀合体)的简单方法,可以通过改善生物分子稳定性和提高循环时间来提高聚合物-蛋白质缀合体的性能。
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