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yin198716

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In addition to a role in tumor angiogenesis, Dll4-Notch signaling also plays a crucial role in T-cell lymphocyte development and differentiation. Gene targeting studies have demonstrated that Notch1 is the essential Notch receptor for T-cell lineage commitment, while Dll4 is the Notch ligand required to induce Notch signaling in thymic immigrant cells and to actively determine T-cell fate. Dll4 is constitutively expressed on the thymic epithelial cells (TEC) as well as on endothelial cells.
Oncology
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Rio2016

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phu_grassman: 金币+2, thanks 2013-03-24 09:20:56
yin198716: 金币+10, 翻译EPI+1, 有帮助 2013-03-24 15:23:47

hookhans

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Farmer

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