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| In earlier studies, the mechanical resistance of proteins has been linked to the orientation of beta-strand domains with respect to the applied load. However, how the number of H-bonds in a strand (or equivalently, the strand length), influences the strength remains divisive. There exist only phenomenological descriptions based on determining the energy barrier and the location of the transition state of mechanical unfolding pathways of proteins, extracted by studying the rate dependence of the mechanical unfolding force and the subsequent analysis with statistical theories. Ôõô·Ò룿±¾ÈËÊÇ´óËÄѧÉú£¬Ñо¿Éúµ¼Ê¦¸øÁ˼¸Æª¹ØÓÚÉúÎï²ÄÁϵÄÎÄÕ£¬È÷Ò룬Íêȫû»ù´¡µÄÎҸе½ºÜ³ÔÁ¦°¡£¬ÓÈÆäÊÇרҵÊõÓï¶¼¸ã²»Ã÷°×£¬ÇóÖú~ |
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fool_proof: ½ð±Ò+1, ¸Ðл»ØÌûÓ¦Öú~ 2013-03-20 21:17:11
fenlovely: ½ð±Ò+1, ¡ïÓаïÖú 2013-03-21 10:11:31
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