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痴梦潇湘

木虫 (著名写手)

应助: 16 (小学生)
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虫号: 1120792
注册: 2010-10-12
性别: GG
专业: 药物化学

[交流] 恒瑞2010-2012临床试验进展情况（共申请17项临床，其中两项已宣告失败）已有5人参与

共有四个替尼类药物进入临床，其中阿帕替尼进入临床III期，氟马替尼进入临床II期，西帕替尼和海那替尼在临床I期被淘汰出局。
具体情况如下：
Apatinib阿帕替尼
NCT01531777 (Phase 2)
First received: July 20, 2010
Status: Recruiting
Condition: Metastatic Breast Cancer

NCT01192971 (Phase 2)
First received: August 30, 2010
Status: Unknown
Condition: Advanced Hepatocellular Carcinoma

NCT01270386 (Phase 2)
First received: December 29, 2010
Status: Completed
Condition: Non-Small-Cell Lung Cancer

NCT01512745 (Phase 3)
First received: January 13, 2012
Status: Recruiting
Condition: Advanced or Metastatic Gastric Cancer

NCT01531777 (Phase 2)
First received: February 7, 2012
Status: Recruiting
Condition: Colorectal Cancer

NCT01653561 (Phase 2)
First received: July 10, 2012
Status: Recruiting
Condition: Breast Neoplasms

Flumatinib氟马替尼
NCT01392235 (Phase 2)
First received: July 3, 2011
Status: Recruiting
Condition: Recurrent and/or Metastatic Nasopharyngeal Carcinoma

NCT01462474 (Phase 1)
First received: October 27, 2011
Status: Recruiting
Condition: Locally Advanced Nasopharyngeal Carcinoma

NCT01503502 (Phase 2)
First received: January 1, 2012
Status: Active, not recruiting
Condition: Chronic Myelogenous Leukemia

NCT01762293 (Phase 2)
First received: January 4, 2013
Status: Recruiting
Condition: Advanced Colorectal Cancer

NCT01653574 (Phase 2)
First received: July 10, 2012
Status: Recruiting
Condition: Breast Neoplasms

NCT01762280 (Phase 1)
First received: December 26, 2012
Status: Active, not recruiting
Condition: Advanced Solid Tumor

Pegylated rhG-CSF重组人粒细胞集落刺激因子
NCT01560195 (Phase 3)
First received: March 8, 2012
Status: Recruiting
Condition: Non-Small-Cell Lung Cancer, Neutropenia, Febrile Neutropenia

NCT01611051 (Phase 3)
First received: May 31, 2012
Status: Completed
Condition: Breast Cancer, Neutropenia, Febrile Neutropenia

Tolvaptan托伐普坦
NCT01507727 (Phase 2)
First received: January 5, 2012
Status: Recruiting
Condition: Non-hypovolemic Non-acute Hyponatremia

Cipatinib西帕替尼
NCT01301911 (Phase 1)
First received: January 28, 2011
Status: Terminated
Condition: Breast Cancer

Henatinib海那替尼
NCT01416623 (Phase 1)
First received: August 12, 2011
Status: Terminated
Condition: Advanced Solid Cancer

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