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liying841216金虫 (初入文坛)
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润色 急 立马发金币
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本研究应用大量家系筛查法，对黑腹果蝇F1代在2:3易位平衡染色体(覆盖黑腹果蝇80％左右的基因组)上发生的与存活率相关的隐性突变进行了筛查，对存活率在0-5％的隐性突变的频率分布进行了统计分析。研究结果表明，黑腹果蝇2:3染色体上的致死突变（存活率小于1%）的突变率为0.0182，在存活率为0-5%的突变中，随着存活率的降低，所观察到的家系的数量反而呈递增的趋势。本研究为果蝇平衡染色体的隐形突变和存活率的相关研究奠定了基础。 Viability recessive mutations on the 2:3 balancer chromosomes (covering about 80% of the Drosophila genome) of Drosophila melanogaster were screened from F1 generations of large number of families. Rate and distribution of mutations of less than 5% survival rate was analysed. The results indicated that, the total lethal mutation (suvival rate<1%) per generation for D. melanogaster 2:3 chromosomes is about 0.0182. This estimation is a little higher than that by previously studies (about 0.015). Furthermore. We found that as survival rate decreased from 5% to 0, number of observed lines increased. We then discussed this distribution pattern. |
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wyky2007136
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liying841216: 金币+50, 翻译EPI+1, ★★★★★最佳答案 2012-03-30 11:43:08
liying841216: 金币+50, 翻译EPI+1, ★★★★★最佳答案 2012-03-30 11:43:08
| Survival-rate-correlated recessive mutations on the 2:3 translocated balancer chromosomes (covering about 80% of the Drosophila genome) of Drosophila melanogaster F1 generations were screened by applying a large number of families. The frequency distribution of the recessive mutations with survival rate of 5% was statistically analyzed. The results indicated that, the mutation rate of the lethal mutation (survival rate smaller than 1%) on 2:3 chromosomes of Drosophila melanogaster is 0.0182; and in the mutation with the survival rate of 0-5%, along with the decrease of the survival rate, the number of the observed families is in a progressive increase tendency. A foundation is laid for researching the correlation between recessive mutation and survival rate of balancer chromosomes of Drosophila. |
2楼2012-03-30 11:40:12