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Nanocosmetics and Nanomedicines: New Approaches for Skin Care2011
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The book "Nanocosmetics and nanomedicines: new approaches for skin care contains a summary of the most important nanocarriers for skin delivery. Although Snanocosmetics is a subject widely commented in the academy and the beauty industry, a book covering the skin care treatments using nanotechnological approaches with cosmetics and nanomedicines is still missing, therefore the need for this publication. This book is divided in three parts: The first one (Part A) is devoted to a brief review on the main topics related to the skin delivery and to the introduction of the subject Snanocosmetics . The second part (Part B) presents different types of nanocarriers applied as skin delivery systems for cosmetics or drugs. The last part (Part C) shows a wide range of applications of nanotechnology on the skin care area as well as on dermatocosmetic and dermatological fields. Cover Nanocosmetics and Nanomedicines ISBN 9783642197918 Forword Contents Part I Fundamentals of Skin Delivery 1 Transport of Substances and Nanoparticles across the Skin and in Vitro Models to Evaluate Skin Permeation and/or Penetration Introduction Transport across the Skin In Vitro Models and Membranes Used to Evaluate Skin Permeation and/or Penetration In Vitro Diffusion Models Microscopy Techniques Membranes Transport of Nanoparticles and Encapsulated Substances across the Skin Nanoparticles Based on Organic Compounds Nanoparticles Based on Inorganic Compounds Concluding Remarks References 2 Rheological Behavior of Semisolid Formulations Containing Nanostructured Systems Introduction Rheology: Fundamental Concepts Rheological Properties of Nanoparticles Incorporated into Semisolids Conclusions References Part II Nanocarriers for Skin Care and Dermatological Treatments 3 Polymeric Nanocapsules: Concepts and Applications Introduction Models of the Supramolecular Structure of Nanocapsules Core Surface Nanocapsule Preparation Chemical Methods Physicochemical Methods Methods of Physicochemical Characterization Nanocapsules in Skin Formulations: Advantages and Challenges Concluding Remarks References 4 Topical Application of Nanostructures: Solid Lipid, Polymeric and Metallic Nanoparticles Introduction Preparation and Characterization of Solid Lipid Nanoparticles (SLN) Hot Microemulsion Emulsification and Solvent Evaporation Solvent Diffusion Method High Pressure Homogenization (HPH) Method X-Ray Diffraction Differential Scanning Calorimetry (DSC) Proton Nuclear Magnetic Resonance (NMR) Microscopy Techniques Preparation and Characterization of Polymeric Nanoparticles Encapsulation Efficiency Dynamic Light Scattering (DLS) Microscopic Techniques In Vitro Drug Release Differential Scanning Calorimetry (DSC) and Other Molecular-Level Methods Preparation and Characterization of Metallic Nanoparticles Topical Application of SLN, and Polymeric and Silver Nanoparticles SLN Application Polymeric Nanoparticles Metallic Nanoparticles Future Perspectives References 5 Lipid Nanoparticles as Carriers for Cosmetic Ingredients: The First (SLN) and the Second Generation (NLC) Introduction Nanocarriers and Skin Interaction Definitions Lipid Nanoparticles Solid Lipid Nanoparticles (SLN) Nanostructured Lipid Carriers (NLC) Preparation of Lipid Nanoparticles Characterization of Lipid Nanoparticles Particle Size Distribution Zeta Potential Physical Stability Kinetics Crystal Structure Morphological Aspects Loading Capacity and Active Agent Incorporation Mechanisms Modulation of Active Agent Release Recent Advances and Advantages of SLN and NLC for Cosmetic Applications Formulations and Products Encapsulation as a Protective Tool The Occlusion Effect The UV Blocking Effect Conclusions and Future Perspectives References 6 Industrial Production of Polymeric Nanoparticles: Alternatives and Economic Analysis Introduction Alternatives Proposal Definitions Investment Cost Production Cost Basic Concepts Methodology Analysis of Economic Viability Production of 10 kg/day Production of 20 kg/day Sensitivity Analysis of Sale Price vs. Production Conclusions References 7 Elastic Liposomes Introduction State-of-Art Technologies Elastic Liposomes Systems Conventional Liposomes Elastic Liposomes Membrane Elasticity Mechanisms Characterization Methods Transdermal Transport of Liposomes Final Remarks References 8 Chitosan as Stabilizer and Carrier of Natural Based Nanostructures Introduction Chitosan as Stabilizer of Nanostructures Chitosan as Carrier of Natural Based Nanostructures Concluding Remarks References Part III Applications of Nanocosmetics and Nanomedicines for Skin Treatments 9 Performance of Elastic Liposomes for Topical Treatment of Cutaneous Leishmaniasis Introduction Cutaneous Leishmaniasis Chemotherapy Topical Treatment of CL Liposomes for Topical Treatment of CL Preparation of Elastic Liposomes Loaded with Chalcone CH8 CH8- Loaded Conventional Liposomes (CH8-CvL) CH8- Loaded Pegylated Liposomes (CH8-PL) CH8-Loaded Liposome Characterization Size Distribution Morphology Phospholipids Concentration Elasticity Biological Assessments of the CH8-Loaded Liposomes In Vitro Skin Permeation Topical Efficacy against Murine CL Conclusion Future Perspectives References 10 Druggable Targets for Skin Photoaging: Potential Application of Nanocosmetics and Nanomedicine Skin Phototoxicity Acute Effects of UV on Skin Chronic Effects of UV on Skin In Vitro Index of Phototoxicity Photo-Irritation Factor Molecular Markers of Skin Inflammation, Senescence and Photoaging Molecular Markers of Inflammation Molecular Marker of Senescence Nanocosmetics and Nanomedicine for Overcoming Skin Photoaging Photoprotection Molecular Action of the Toxicity of Carbon Nanotubes in Skin Cells Final Remarks References 11 Nanomedicine: Potential Killing of Cancercells Using Nanoparticles General Introduction Apoptosis Apoptosis Cell Death: Biochemistry and Molecular Aspects Cell Death by Apoptosis Signaling Cell Death and Cancer Nanomedicine for the Management of Cancer Cells Polymeric Nanoparticles Silver Nanoparticles Future Perspectives References 12 Zebrafish as a Suitable Model for Evaluating Nanocosmetics and Nanomedicines Introduction Biology of Zebrafish Zebrafish as a Correlative and Predictive Model for Measuring Biomaterial Nanotoxicity Screening of Skin Care Products Based on Zebrafish Development Future Perspectives References 13 Nitric Oxide-Releasing Nanomaterials and Skin Care Nitric Oxide and Skin: Current Status The Role of NO in Physiologic Responses in the Skin NO and Skin Diseases NO and Wound Healing Nanotechnology and NO in Skin Treatments NO and Skin Pigmentation Enhancers Future Directions and Challenges in Dermatological Therapeutics References 14 Nanocarriers and Cancer Therapy: Approaches to Topical and Transdermal Delivery Nanotechnology in Healthcare: Evolution Technological Advances: Nanotechnology and Cancer New Strategies for Topical and Transdermal Treatment of Cancer Target Delivery Chemical and Formulation Enhancers of Skin Penetration and Permeation Physical Methods: Iontophoresis, Sonophoresis, and Electroporation Microneedles Final Considerations References 15 Nanocarriers to Deliver Photosensitizers in Topical Photodynamic Therapy and Photodiagnostics Topical Photodynamic Therapy General Considerations Skin Cancer and Non-neoplastic Disorders Photosensitizers and Precursors Skin as Administration Site for Topical PDT Skin Structure, Barrier and Permeability Drug Delivery Systems in Topical PDT Future Directives References 16 Production of Nanofibers by Electrospinning Technology: Overview and Application in Cosmetics Overview Introduction History of Nanofibers Obtained by Electrospinning Preparation of Nanofiber by Electrospinning Technology Polymers Used in the Electrospinning Process Electrospinning Process Control Parameters Characterization of Electrospun Nanofibers Application of Polymer Nanofibers Application of Polymeric Nanofibers in Cosmetics Future Perspectives of Nanofibers by Electrospinning in Cosmetic Application References 17 Nanosized and Nanoencapsulated Sunscreens Introduction Nanosized UV Filters TiO2 and ZnO-Induced Cytotoxicity and Genotoxicity Skin Penetration Novel nanosized UV filters Nanoencapsulated UV Filters Skin Penetration Photostability UV-Blocking Ability Nanoparticles in Sunscreens Today: The Commercial Arena Conclusions References About the Editors Subject Index CnGTVL5r3VMC  [ 来自科研家族 小木虫青春动力 ] |
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