| ²é¿´: 486 | »Ø¸´: 2 | ||
| ±¾Ìû²úÉú 1 ¸ö ·ÒëEPI £¬µã»÷ÕâÀï½øÐв鿴 | ||
ÑÌÔÆÌýÓêÌú¸Ëľ³æ (ÕýʽдÊÖ)
½ð³æ
|
[ÇóÖú]
Çó·ÒëÒ»¶ÎÓ¢ÎÄ£¨Ò©»¯£©
|
|
|
Notably,neither of the naturally occurring alkaloids tested had activity at any of the opioid receptors. Although Sig-R binding mediates the activity of some nonnarcotic antitussive agents, such as dextrophan(41), the lack of Sig-R binding in neostenine indicates that the source of this antitussive activity of this compound is still unknown. Target identification studies, along with the independent validation of the in vivo literature results, are called for but beyond the scope of the present paper. |
» ²ÂÄãϲ»¶
085600²ÄÁÏÓ뻯¹¤Çóµ÷¼Á
ÒѾÓÐ3È˻ظ´
311Çóµ÷¼Á
ÒѾÓÐ7È˻ظ´
303Çóµ÷¼Á
ÒѾÓÐ3È˻ظ´
ÓÐûÓеÀÌú/ÍÁľµÄÏëµ÷¼ÁÄÏÁÖ£¬¸ø×Ô¼ºÕÐʦµÜÖС«
ÒѾÓÐ7È˻ظ´
Áº³ÉΰÀÏʦ¿ÎÌâ×é»¶ÓÄãµÄ¼ÓÈë
ÒѾÓÐ10È˻ظ´
Ò»Ö¾Ô¸ËÕÖÝ´óѧ²ÄÁϹ¤³Ì£¨085601£©×¨Ë¶ÓпÆÑоÀúÈýÏî¹ú½±Á½¸öʵÓÃÐÍרÀûÒ»ÏîÊ¡¼¶Á¢Ïî
ÒѾÓÐ8È˻ظ´
070300»¯Ñ§319Çóµ÷¼Á
ÒѾÓÐ3È˻ظ´
Ò»Ö¾Ô¸Ìì½ò´óѧ»¯Ñ§¹¤ÒÕרҵ£¨081702£©315·ÖÇóµ÷¼Á
ÒѾÓÐ4È˻ظ´
268Çóµ÷¼Á
ÒѾÓÐ7È˻ظ´
290Çóµ÷¼Á
ÒѾÓÐ11È˻ظ´

8814402
ÖÁ×ðľ³æ (Ö°Òµ×÷¼Ò)
- ·ÒëEPI: 509
- Ó¦Öú: 18 (СѧÉú)
- ¹ó±ö: 0.381
- ½ð±Ò: 12916.1
- É¢½ð: 47
- ºì»¨: 16
- Ìû×Ó: 4183
- ÔÚÏß: 357.8Сʱ
- ³æºÅ: 1184404
- ×¢²á: 2011-01-06
- רҵ: Ò©ÎïѧÆäËû¿ÆÑ§ÎÊÌâ
¡¾´ð°¸¡¿Ó¦Öú»ØÌû
¡ï
ÑÌÔÆÌýÓê(½ð±Ò+8, ·ÒëEPI+1): лл 2011-07-19 12:26:24
Mally89(½ð±Ò+1): ¸ÐлӦÖú£¡~ 2011-07-23 22:07:01
ÑÌÔÆÌýÓê(½ð±Ò+8, ·ÒëEPI+1): лл 2011-07-19 12:26:24
Mally89(½ð±Ò+1): ¸ÐлӦÖú£¡~ 2011-07-23 22:07:01
| Notably,neither of the naturally occurring alkaloids tested had activity at any of the opioid receptors.ÖµµÃ×¢ÒâµÄÊÇ£¬ÊÔÑé¹ýµÄÌìÈ»´æÔÚÉúÎï¼î¾ùÎÞ°¢Æ¬ÊÜÌå»îÐÔ¡£ Although Sig-R binding mediates the activity of some nonnarcotic antitussive agents, such as dextrophan(41), the lack of Sig-R binding in neostenine indicates that the source of this antitussive activity of this compound is still unknown. ¾¡¹ÜSig-R ½áºÏ½éµ¼ÁËijЩ·ÇÂé×íÐÔÕò¿È¼ÁÈçÓÒÐýÂð·ÈµÄ»îÐÔ£¬µ«ÐÂË¹ÌæÄþ¼îȱ·¦ÓëSig-RµÄ½áºÏÌáʾ´Ë»¯ºÏÎïÕò¿È»îÐÔÔ´×Ժδ¦Éв»µÃ¶øÖª¡£Target identification studies, along with the independent validation of the in vivo literature results, are called for but beyond the scope of the present paper.°Ð±êʶ±ðÒÔ¼°¶ÔÌåÄÚÑо¿ÎÄÏ×½á¹ûµÄ¶ÀÁ¢ÑéÖ¤¶¼ÊǼ±ÐèµÄ¹¤×÷£¬µ«±¾ÎÄδÓèÉæ¼°¡£ |
2Â¥2011-07-19 08:53:20
ÑÌÔÆÌýÓê
Ìú¸Ëľ³æ (ÕýʽдÊÖ)
½ð³æ
- Ó¦Öú: 3 (Ó×¶ùÔ°)
- ½ð±Ò: 8375.9
- É¢½ð: 64
- ºì»¨: 7
- Ìû×Ó: 482
- ÔÚÏß: 397.4Сʱ
- ³æºÅ: 1080278
- ×¢²á: 2010-08-23
- ÐÔ±ð: GG
- רҵ: ½ðÊôÓлú»¯Ñ§

3Â¥2011-07-19 21:02:51













»Ø¸´´ËÂ¥