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【答案】应助回帖
★ ★
sltmac(金币+2): 感谢应助~~ 2011-06-25 11:26:31
xzf_23(金币+30, 翻译EPI+1): 感谢 2011-06-26 12:06:43
题目 A Short Total Synthesis of (±)-Epimeloscine and (±)-Meloscine Enabled by a Cascade Radical Annulation of a Divinylcyclopropane一种简短的通过Divinylcyclopropane串联自由基环化实现的(±)-Epimeloscine 和 (±)-Meloscine全合成方法
摘要 ABSTRACT: The first stereoselective synthesis of epimeloscine has been accomplished in 13 total steps with a longest linear sequence of 10 steps.首先，epimeloscine的立体选择性合成通过总计13步包括一个最长的线性次序10步反应实现。 The core of the synthesis takes only five steps, the key ones being acylation, stereoselective tandem radical cyclization of a divinylcyclopropane to make two rings, and group-selective ring-closing metathesis of the resulting divinylcyclopentane to make the last ring.合成的核心反应只需要5步，关键步骤包括酰化、divinylcyclopropane的立体选择性串联自由基环化形成两个环和所得divinylcyclopentane的官能团选择性合环歧化形成最后的环。
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