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于田9858木虫 (小有名气)
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The present work focuses on quantifying the dispersion and separation resolution of a continuous hydrodynamic particle separation technique. We have developed a compact analytical expression for particle dispersion and separation resolution that accounts for Brownian motion and wall roughness. We measure the dispersion and separation resolution as a function of the device pinched width dimensions (15-30 ím), device aspect ratio (20- 30 approximately), and particle diameter difference (2-15 ím). We show that the device wall roughness plays a key role in the dispersion and separation resolution. Mylar masks result in rough side walls and compromised device performance. We observe that particles appear closer to the sidewall than predicted by linear theory which results in lower separation resolution. In this study, dispersion due to wall roughness is a limiting factor for obtaining high-resolution separations. Our results suggest that particles whose diameters are of the order of the wall roughness cannot be separated using PFF. The results show separation resolutions greater than unity can be obtained for devices having aspect ratios larger than 20 and particle size differences greater than 10 ím. A better theoretical model for dispersion due to wall roughness is needed that incorporates the effect of advection of particles near the wall that may depend on the Peclet number in this region. Future work may also include high fidelity computational modeling that will predict why particles move closer to the wall than predicted by linear theory. |
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sltmac(金币+1): 谢谢交流~~ 2011-06-15 13:29:28
于田9858(金币+15, 翻译EPI+1): 谢谢，回晚了，见谅 2011-06-17 09:13:50
sltmac(金币+1): 谢谢交流~~ 2011-06-15 13:29:28
于田9858(金币+15, 翻译EPI+1): 谢谢，回晚了，见谅 2011-06-17 09:13:50
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研究中我们发现一种粒子离差和间隔分辨的压缩分析现象，在布朗运动和壁粗方面占有很大比例。通过测量离差和间隔分辨率，得出作为一种装置功能，它的紧缩宽度为15-30ím，装置屏幕高度比大约为20-30ím，而粒子直径差异为2-15 ím。从上以可看出，装置的壁面粗糙度在离差和间隔分辨上具有重要作用。聚酯薄膜面引起粗糙度并包含 装置性能。我们观察到粒子要更紧密，相比于预测的导致较低间隔分辨率的线性理论来说。 研究表明，由于壁面粗糙度而产生的离差是限制产生高分辨率间隔的一个重要因素。而里面序列分布的壁粗的粒子是不能用PFF来分隔的。以上结果显示分辨率比整体要大，这样装置的纵横比大于20,粒度差大于 10 ím 。鉴于壁面的粗糙度，赖于peclet数的影响，离差更好的理论模型可以用来合并粒子的近壁面的对流效应。在将来的研究中，将会利用高保真计算机建模来研究粒子比线性理论预测的要向壁面移动紧密的原因。 |
2楼2011-06-15 10:22:46
