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王连磊(金币+10, 博学EPI+1): 谢谢 2011-04-05 10:31:19
不保证没语法错误，你先看看吧
Abstract：
Purpose：synthesize 5-hydroxyindole
Method: take 3-methyl-4-nitro-phenol as substrate, then treat it with hydroxy group protection, nitroreduction, ring-closure reaction and catalytic debenzylation,finaly get 5-hydroxyindole as product.
Result: the structure of the desired product has been confirmed with 1H-NMR spectrum, and the total yield is 32%.
Conclusion: this process is easily to operate, the reaction conditions are mild, and it’s easy to control the product’s quality.
Key words: 5-hydroxyindole, synthesize, medical intermediate |
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