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jingbo73

金虫 (小有名气)


[交流] 【请教】1个A类错误

A-----Structure Contains Solvent Accessible VOIDS of .        229 A**3
Type_2 Test for (Unreported) solvent accessible voids
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Crystal structures in general do not contain large solvent accessible voids
in the lattice. Most structures lose their long-range ordering when solvent
molecules leave the crystal. Only when the remaining network is strongly
bonded (e.g. zeolites and some hydrogen bonded networks) the crystal
structure may survive.
Residual voids in a structure may indicate the omission of (disordered)
density from the model. Disordered density may go undetected when smeared
since peak search programs are not designed to locate maxima on density
ridges. The presence or absence of residual density in the void may be
verified on a printed/plotted difference Fourier map or with PLATON/SQUEEZE.
Voids of 40 Ang**3 may accommodate H2O. Small molecules such as
Tetrahydrofuran have typical volumes in the 100 to 200 Ang**3 range.
This test reports the volume of the largest solvent accessible void in the
structure.
A paper reporting a crystal structure with a significant solvent accessible
void should at the least discuss the issue.


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xi2004

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jingbo73(金币+2): 2011-07-19 17:04:06
有溶剂分子未加。
应尽量加全。不要忽略小的 残余峰,1左右也算的,有时候。

实在不行, 就用squeez
2楼2011-04-01 08:42:30
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bswk

铜虫 (著名写手)


jingbo73(金币+3): 2011-07-19 17:04:14
结构中原子没有找全
3楼2011-04-01 08:44:26
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