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| xcretion and that the patients have partially compensated for the hypoxia in another anner.In other cases of polycythemia an inappropriate increase in Ep production is present,since no physiologic hypoxic stimulus can be identified.The increased Ep in these patients appears to arise autonomously and is associated predom-inantly with renal lesions such as cysts,hydronephrosis,adenomas,and car-cinomas,but also with cerebellar hemangioblastomas,hepatomas,uterine leiomyomas,and a variety of tumors and hyperplasias of the endocrine organs.levels are depressed and phlebotomy induces only a modest increase in urinary Ep(102,103).The white cell and platelet counts are often increased,since the disease is not limited to abnormal red cell production.short-term cultures of marrow cells from patients with polycythemia vera indicated that the Ep-stimulated incrEp has been extracted from some of these tumors,and phlebotomy results in no further |
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ringzhu(金币+10): 辛苦 欢迎常来~~ 2011-03-27 11:15:11
ringzhu(金币+10): 辛苦 欢迎常来~~ 2011-03-27 11:15:11
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4楼2011-03-13 22:24:21
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ringzhu(金币+10, 翻译EPI+1): ~~ 2011-03-27 11:14:57
ringzhu(金币+10, 翻译EPI+1): ~~ 2011-03-27 11:14:57
| In other cases of polycythemia an inappropriate increase in Ep production is present,since no physiologic hypoxic stimulus can be identified. 在其他红细胞增多症病例中，存在不适当的红细胞生成素生成增加的情形，因为没有生理缺氧刺激可以与之相联系。The increased Ep in these patients appears to arise autonomously and is associated predom-inantly with renal lesions such as cysts,hydronephrosis,adenomas,and car-cinomas,but also with cerebellar hemangioblastomas,hepatomas,uterine leiomyomas,and a variety of tumors and hyperplasias of the endocrine organs.在这些病人中增加的红细胞生成素似乎是自发升高的，而且主导性地与肾损伤如囊肿、肾积水、肾上腺瘤、肿瘤相关联，而且还与小脑血管母细胞瘤、肝癌、子宫肌瘤以及多种肿瘤和内分泌器官的增生相关。 |
2楼2011-03-07 15:38:40
3楼2011-03-07 15:39:31
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