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da_da

金虫 (小有名气)


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This hypothesis is further supported by the finding that immunization of cattle with A.marginale derived from infected erythrocytes in which MSP1a is upregulated with respect to MSP1b and probably exists uncoupled to MSP1b, provided a level of protection comparable to that observed in cattle immunized with recombinant MSP1a and A. marginale derived from infected tick cells, in which MSP1a is downregulated and most likely exists only in the MSP1 complex with MSP1b.
Another factor to be considered for the induction of a protective immune response against A. marginale is the role of sugar moieties of MSP1a in the protection properties, which may also contribute to the generation of a neutralizing response in cattle.
老师给的翻译里面的两句话,怎么也翻译不通。大家帮帮忙啊!
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zhxiaotai

木虫 (著名写手)


da_da(金币+8, 翻译EPI+1): 2011-01-08 11:23:07
这种假设通过下面的发现得到进一步的证实,用边缘体A对牛进行免疫,边缘体A从感染的红血球中提取,而在这些红血球中,MSP1a根据MSP1b进行上调,并且其中很可能存在未耦合的MSP1b,因此与用重组的MSP1a和边缘体A对牛进行的免疫相比,能提供一定水平的保护,重组的MSP1a和边缘体A是从壁虱(动物身上的寄生虫)细胞中得到的,在壁虱细胞中,MSP1a被下调并且很有可能只存在于MSP1a和MSP1b的复合物中。
对应边缘体A的保护性免疫反应的诱导,需要考虑的另一个因素是在防护性能中MSP1a所含糖基的作用,这些糖基在牛体内或许也有利于中和反应的发生。

下面这个网站也许对你理解有所帮助:https://d.wanfangdata.com.cn/Periodical_zgsykj200911017.aspx
2楼2011-01-08 10:17:49
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kaobo2012

木虫 (正式写手)


da_da(金币+2): 2011-01-08 11:23:21
这是我自己翻译的,翻译能力实在不怎么样,希望对楼主有帮助!


This hypothesis(主) is further supported(系) by the finding(表) that(定后面整句) immunization(主) of cattle with A.marginale derived from infected erythrocytes in which (定infected erythrocytes)MSP1a is upregulated with respect to MSP1b and probably exists(与is upregulated并列) uncoupled to MSP1b, provide(谓) a level (宾)  of protection comparable to that(主) observed in cattle immunized with recombinant MSP1a and A. marginale derived from infected tick cells, in which(定infected tick cells) MSP1a is downregulated and most likely exists (与is downregulated并列) only in the MSP1 complex with MSP1b.
这种假说得到了新发现的进一步支持,该发现是用取自感染胚胎细胞的marginale免疫小牛,在感染的胚胎细胞中, MSP1a 相对于 MSP1b是上调的,可能存在形式也不与 MSP1b二聚化。与取自感染剔细胞的重组 MSP1a 和marginale免疫小牛,感染剔细胞中 MSP1a是下调的,存在形式更可能是与 MSP1b结合的 MSP1a复合物。相比之下,前者保护能力更强。

Another factor (主) to be considered for the induction of a protective immune response against A. marginale is (系) the role (表) of sugar moieties of MSP1a in the protection properties, which may also contribute to the generation of a neutralizing response in cattle.
值得思考的诱导抗A. marginale的保护性免疫反应的另一个因素是在保护性能中MSP1a自身糖那部分的作用,这种保护性能在小牛中可能促进中和反应的产生。
3楼2011-01-08 11:03:42
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