²é¿´: 2210  |  »Ø¸´: 3
±¾Ìû²úÉú 1 ¸ö ·­ÒëEPI £¬µã»÷ÕâÀï½øÐв鿴
µ±Ç°Ö»ÏÔʾÂú×ãÖ¸¶¨Ìõ¼þµÄ»ØÌû£¬µã»÷ÕâÀï²é¿´±¾»°ÌâµÄËùÓлØÌû

baishitou3

½ð³æ (СÓÐÃûÆø)

[½»Á÷] ÖØ½ðÇó»¯Ñ§ºÏ³É·­Ò룬¸ßÊÖ½øÀ´Ö¸µ¼Ö¸µ¼

To a flame-dried
Schlenk test tube with a magnetic stirring bar was charged CuI
(38.2  mg,  0.2  mmol),  Cs 2 CO 3 (0.65  g,  2.0  mmol),  nitrogen-
containing heterocycle (1.4 mmol), aryl or heteroaryl halide (1.0
mmol), and DMF (2 mL) under N 2 . A rubber septum was replaced
with a glass stopper, and the system was then evacuated twice and
back filled with N 2 . The reaction mixture was stirred for 30 min at
room temperature, and then heated at 120 ¡ãC for 40 h. The reaction
mixture was then cooled to ambient temperature, diluted with 2-3
mL of ethyl acetate, filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate. The combined organic extracts
were concentrated, and the resulting residue was purified by column
chromatography on silica gel to provide the desired product.
ÒÔÉÏÊÇÒ»¶ÎºÏ³ÉµÄ²½Ö裬filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate. The combined organic extracts
were concentrated,ÕâÒ»¶Î·Ç³£µÄÄѶ®°¡£¬¸ßÊÖÃǽøÀ´¿´¿´£¬Ö¸µ¼Ö¸µ¼°¡

» ²ÂÄãϲ»¶

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

slowstar

ľ³æ (Ö°Òµ×÷¼Ò)

ÄÇÒ»¶ÎºÏ³ÉµÄ²½Ö裬ÄãÓ¦¸ÃÄõÃÏÂÀ´¡£
¾«ÈͲ»µ¡£¬ÈÕ½øÓй¦
4Â¥2010-09-20 22:23:19
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
²é¿´È«²¿ 4 ¸ö»Ø´ð

cfk580713

ÖÁ×ðľ³æ (ÖøÃûдÊÖ)

¡ï ¡ï ¡ï ¡ï
wypward(½ð±Ò+1):лл²ÎÓë 2010-09-20 20:49:10
baishitou3(½ð±Ò+2, ·­ÒëEPI+1): 2010-09-27 08:40:11
baishitou3(½ð±Ò+2): 2010-10-04 22:06:22
ringzhu(½ð±Ò+3): 2010-11-22 12:32:12
¹ýÂ˳ýÈ¥²»ÈÜÎï°É£¬ÔÙÓÃÒÒËáÒÒõ¥Ï´µÓ£¬Ö®ºóºÏ²¢Óлú²ã£¬ÖùÉ«Æ×·ÖÀë
2Â¥2010-09-20 16:16:33
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

slowstar

ľ³æ (Ö°Òµ×÷¼Ò)

¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
·¢Ñ¿ÍÁ¶¹(½ð±Ò+2):лл²ÎÓë 2010-09-23 09:46:24
baishitou3(½ð±Ò+5): 2010-09-27 08:40:33
baishitou3(½ð±Ò+2): 2010-10-04 22:06:17
ringzhu(½ð±Ò+6): 2010-11-22 12:32:07
filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate.
The combined organic extracts were concentrated, and the resulting residue was purified by column
chromatography on silica gel to provide the desired product.
£¨ÔÚɰÐÄ©¶·»ò²¼ÊÏ©¶·ÀÏÈÌîÉÏЩ¹è½º£¬È»ºó³éÂË£¬ÔÙÓÃ10-20 mLÒÒËáÒÒõ¥ÁÜÏ´¡£ºÏ²¢ËùµÃÂËÒº£¨¼´³éÂ˺ÍÒÒËáÒÒõ¥ÁÜÏ´ËùµÃµÄÂËÒº£©£¬½«ÂËҺŨËõ£¨ÓÃÐýתÕô·¢ÒÇ×î·½±ãÁË£©ºóËùµÃµÄÊ£ÓàÎï¹ý¹è½ºÖù£¨¼´ÓлúºÏ³ÉÉÏË׳ƵĹýÖù×Ó£©£¬¼´¿ÉµÃµ½ËùÐè²úÎï¡£
¾«ÈͲ»µ¡£¬ÈÕ½øÓй¦
3Â¥2010-09-20 22:21:45
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 340Çóµ÷¼Á +4 »°Ã·ÌÇ111 2026-03-24 4/200 2026-03-24 21:41 by yuyu98412
[¿¼ÑÐ] 311Çóµ÷¼Á +3 ¶¬Ê®Èý 2026-03-24 3/150 2026-03-24 21:31 by peike
[¿¼ÑÐ] 0854µç×ÓÐÅÏ¢Çóµ÷¼Á +6 ¦Á____ 2026-03-22 7/350 2026-03-24 19:46 by sunjie8888
[¿¼ÑÐ] 085602 289·ÖÇóµ÷¼Á +5 WWWÎ÷Î÷¸¥Ë¹ 2026-03-24 5/250 2026-03-24 18:51 by jhhcooi
[¿¼ÑÐ] ÕÐ08¿¼Êýѧ +7 laoshidan 2026-03-20 16/800 2026-03-24 17:52 by ÎÚÀ­¶ùɽÂö
[¿¼ÑÐ] 306Çó0703µ÷¼ÁÒ»Ö¾Ô¸»ªÖÐʦ·¶ +10 Ö½Óãly 2026-03-21 11/550 2026-03-24 17:22 by qingfeng258
[¿¼ÑÐ] 070300»¯Ñ§Çóµ÷¼Á +9 Ô·¶¹¶¹ 2026-03-20 9/450 2026-03-24 17:15 by licg0208
[¿¼ÑÐ] 292Çóµ÷¼Á +4 ¶ì¶ì¶ì¶î¶î¶î¶î¶ 2026-03-24 4/200 2026-03-24 16:41 by peike
[¿¼ÑÐ] 361Çóµ÷¼Á +3 Glack 2026-03-22 3/150 2026-03-23 22:03 by fuyu_
[¿¼ÑÐ] 336Çóµ÷¼Á +4 ÊÕµ½VS 2026-03-20 4/200 2026-03-23 19:02 by macy2011
[¿¼ÑÐ] 291 Çóµ÷¼Á +4 »¯¹¤2026½ì±ÏÒµÉ 2026-03-21 5/250 2026-03-23 16:46 by »¯¹¤2026½ì±ÏÒµÉ
[¿¼ÑÐ] Ò»Ö¾Ô¸ÄϾ©Àí¹¤´óѧ085701×ÊÔ´Óë»·¾³302·ÖÇóµ÷¼Á +5 ¿ûè÷ÎÀ¶Ó 2026-03-18 7/350 2026-03-23 16:26 by lingjue
[¿¼ÑÐ] 333Çóµ÷¼Á +6 87639 2026-03-21 10/500 2026-03-23 10:41 by Iveryant
[¿¼ÑÐ] 318Çóµ÷¼Á +4 plumÀî×Ó 2026-03-21 7/350 2026-03-22 14:17 by ColorlessPI
[¿¼ÑÐ] 354Çóµ÷¼Á +7 Tyoumou 2026-03-18 10/500 2026-03-22 11:11 by ÈËÀ´Ê¢
[»ù½ðÉêÇë] ɽ¶«Ê¡ÃæÉÏÏîÄ¿ÏÞ¶îÆÀÉó +4 ʯÈð0426 2026-03-19 4/200 2026-03-22 08:50 by Wei_ren
[¿¼ÑÐ] Ò»Ö¾Ô¸»ªÖпƼ¼´óѧ071000£¬Çóµ÷¼Á +4 ÑØ°¶Óб´¿Ç6 2026-03-21 4/200 2026-03-22 07:21 by ilovexiaobin
[¿¼ÑÐ] Çóµ÷¼Á +3 13341 2026-03-20 3/150 2026-03-21 18:28 by ѧԱ8dgXkO
[¿¼ÑÐ] 0805²ÄÁÏ320Çóµ÷¼Á +3 ÉÎïÓï 2026-03-20 3/150 2026-03-21 15:46 by Î޼ʵIJÝÔ­
[¿¼ÑÐ] 332Çóµ÷¼Á +3 ·ï»ËÔº¶¡Õæ 2026-03-20 3/150 2026-03-21 10:27 by luoyongfeng
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û