²é¿´: 2209  |  »Ø¸´: 3
±¾Ìû²úÉú 1 ¸ö ·­ÒëEPI £¬µã»÷ÕâÀï½øÐв鿴
µ±Ç°Ö»ÏÔʾÂú×ãÖ¸¶¨Ìõ¼þµÄ»ØÌû£¬µã»÷ÕâÀï²é¿´±¾»°ÌâµÄËùÓлØÌû

baishitou3

½ð³æ (СÓÐÃûÆø)

[½»Á÷] ÖØ½ðÇó»¯Ñ§ºÏ³É·­Ò룬¸ßÊÖ½øÀ´Ö¸µ¼Ö¸µ¼

To a flame-dried
Schlenk test tube with a magnetic stirring bar was charged CuI
(38.2  mg,  0.2  mmol),  Cs 2 CO 3 (0.65  g,  2.0  mmol),  nitrogen-
containing heterocycle (1.4 mmol), aryl or heteroaryl halide (1.0
mmol), and DMF (2 mL) under N 2 . A rubber septum was replaced
with a glass stopper, and the system was then evacuated twice and
back filled with N 2 . The reaction mixture was stirred for 30 min at
room temperature, and then heated at 120 ¡ãC for 40 h. The reaction
mixture was then cooled to ambient temperature, diluted with 2-3
mL of ethyl acetate, filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate. The combined organic extracts
were concentrated, and the resulting residue was purified by column
chromatography on silica gel to provide the desired product.
ÒÔÉÏÊÇÒ»¶ÎºÏ³ÉµÄ²½Ö裬filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate. The combined organic extracts
were concentrated,ÕâÒ»¶Î·Ç³£µÄÄѶ®°¡£¬¸ßÊÖÃǽøÀ´¿´¿´£¬Ö¸µ¼Ö¸µ¼°¡

» ²ÂÄãϲ»¶

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

slowstar

ľ³æ (Ö°Òµ×÷¼Ò)

¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
·¢Ñ¿ÍÁ¶¹(½ð±Ò+2):лл²ÎÓë 2010-09-23 09:46:24
baishitou3(½ð±Ò+5): 2010-09-27 08:40:33
baishitou3(½ð±Ò+2): 2010-10-04 22:06:17
ringzhu(½ð±Ò+6): 2010-11-22 12:32:07
filtered through a plug of silica gel, and washed
with 10-20 mL of ethyl acetate.
The combined organic extracts were concentrated, and the resulting residue was purified by column
chromatography on silica gel to provide the desired product.
£¨ÔÚɰÐÄ©¶·»ò²¼ÊÏ©¶·ÀÏÈÌîÉÏЩ¹è½º£¬È»ºó³éÂË£¬ÔÙÓÃ10-20 mLÒÒËáÒÒõ¥ÁÜÏ´¡£ºÏ²¢ËùµÃÂËÒº£¨¼´³éÂ˺ÍÒÒËáÒÒõ¥ÁÜÏ´ËùµÃµÄÂËÒº£©£¬½«ÂËҺŨËõ£¨ÓÃÐýתÕô·¢ÒÇ×î·½±ãÁË£©ºóËùµÃµÄÊ£ÓàÎï¹ý¹è½ºÖù£¨¼´ÓлúºÏ³ÉÉÏË׳ƵĹýÖù×Ó£©£¬¼´¿ÉµÃµ½ËùÐè²úÎï¡£
¾«ÈͲ»µ¡£¬ÈÕ½øÓй¦
3Â¥2010-09-20 22:21:45
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
²é¿´È«²¿ 4 ¸ö»Ø´ð

cfk580713

ÖÁ×ðľ³æ (ÖøÃûдÊÖ)

¡ï ¡ï ¡ï ¡ï
wypward(½ð±Ò+1):лл²ÎÓë 2010-09-20 20:49:10
baishitou3(½ð±Ò+2, ·­ÒëEPI+1): 2010-09-27 08:40:11
baishitou3(½ð±Ò+2): 2010-10-04 22:06:22
ringzhu(½ð±Ò+3): 2010-11-22 12:32:12
¹ýÂ˳ýÈ¥²»ÈÜÎï°É£¬ÔÙÓÃÒÒËáÒÒõ¥Ï´µÓ£¬Ö®ºóºÏ²¢Óлú²ã£¬ÖùÉ«Æ×·ÖÀë
2Â¥2010-09-20 16:16:33
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

slowstar

ľ³æ (Ö°Òµ×÷¼Ò)

ÄÇÒ»¶ÎºÏ³ÉµÄ²½Ö裬ÄãÓ¦¸ÃÄõÃÏÂÀ´¡£
¾«ÈͲ»µ¡£¬ÈÕ½øÓй¦
4Â¥2010-09-20 22:23:19
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 0703»¯Ñ§µ÷¼Á£¬Çóµ¼Ê¦ÊÕ +3 ÌìÌìºÃÔËÀ´Éϰ¶° 2026-03-24 3/150 2026-03-24 13:24 by allen-yin
[¿¼ÑÐ] Ò»Ö¾Ô¸¹þ¹¤´ó£¬085400£¬320£¬Çóµ÷¼Á +3 gdlf9999 2026-03-24 3/150 2026-03-24 10:08 by ²«»÷518
[¿¼ÑÐ] Ò»Ö¾Ô¸±±¾©»¯¹¤´óѧ 070300 ѧ˶ 336·Ö Çóµ÷¼Á +7 vvÃÔ 2026-03-22 7/350 2026-03-23 23:44 by Txy@872106
[¿¼ÑÐ] 335·Ö | ²ÄÁÏÓ뻯¹¤×¨Ë¶ | GPA 4.07 | ÓпÆÑо­Àú +4 cccchenso 2026-03-23 4/200 2026-03-23 23:00 by Ðìckkk
[¿¼ÑÐ] 284Çóµ÷¼Á +3 yanzhixue111 2026-03-23 6/300 2026-03-23 22:58 by pswait
[¿¼ÑÐ] 333Çóµ÷¼Á +3 ALULU4408 2026-03-23 3/150 2026-03-23 19:04 by macy2011
[¿¼ÑÐ] 303Çóµ÷¼Á +4 ԪϦԪ 2026-03-20 4/200 2026-03-23 19:00 by macy2011
[¿¼ÑÐ] 0854µç×ÓÐÅÏ¢Çóµ÷¼Á 324 +3 Promise-jyl 2026-03-23 3/150 2026-03-23 13:43 by wangkm
[¿¼ÑÐ] ÇóÀÏʦÊÕÎÒ +3 zzh16938784 2026-03-23 3/150 2026-03-23 12:56 by ztnimte
[¿¼²©] ÕÐÊÕ²©Ê¿1-2ÈË +3 QGZDSYS 2026-03-18 4/200 2026-03-22 10:25 by QGZDSYS
[¿¼ÑÐ] 286·ÖÈ˹¤ÖÇÄÜרҵÇëÇóµ÷¼ÁÔ¸Òâ¿ç¿¼£¡ +4 lemonzzn 2026-03-17 8/400 2026-03-21 22:49 by lemonzzn
[¿¼ÑÐ] 296Çóµ÷¼Á +4 www_q 2026-03-20 4/200 2026-03-21 17:26 by ѧԱ8dgXkO
[¿¼ÑÐ] 266Çóµ÷¼Á +3 ÍÛºôºßºôºß 2026-03-20 3/150 2026-03-21 16:46 by barlinike
[¿¼ÑÐ] 22 350 ±¾¿Æ985Çóµ÷¼Á£¬ÇóÀϵÇÊÕÁô +3 ÀîéóÄÐ003 2026-03-20 3/150 2026-03-21 13:28 by ²«»÷518
[¿¼ÑÐ] Çóµ÷¼Á +6 Mqqqqqq 2026-03-19 6/300 2026-03-21 08:04 by JourneyLucky
[¿¼ÑÐ] Çóµ÷¼Á£¬Ò»Ö¾Ô¸:ÄϾ©º½¿Õº½Ìì´óѧ´óѧ £¬080500²ÄÁÏ¿ÆÑ§Ó빤³Ìѧ˶£¬×Ü·Ö289·Ö +4 @taotao 2026-03-19 4/200 2026-03-20 22:14 by JourneyLucky
[¿¼ÑÐ] AÇøÏß²ÄÁÏѧµ÷¼Á +5 ÖÜÖÜÎÞ¼« 2026-03-20 5/250 2026-03-20 21:33 by laoshidan
[¿¼ÑÐ] 0856µ÷¼Á£¬ÊÇѧУ¾ÍÈ¥ +8 sllhht 2026-03-19 9/450 2026-03-20 14:25 by ÎÞи¿É»÷111
[¿¼ÑÐ] 0703»¯Ñ§µ÷¼Á +3 ÄÝÄÝninicgb 2026-03-17 3/150 2026-03-18 10:29 by macy2011
[¿¼²©] 26²©Ê¿ÉêÇë +3 1042136743 2026-03-17 3/150 2026-03-17 23:30 by ÇáËɲ»ÉÙËæ
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û