| 查看: 1577 | 回复: 13 | |||
| 本帖产生 1 个 翻译EPI ，点击这里进行查看 | |||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | |||
chzhbin金虫 (职业作家)
|
[交流]
【求助】翻译 很简单
|
||
| 摘要：白黎芦醇(resveratrol,3,4',5—三羟基—二苯乙烯)为多酚类化合物，是一种存在于自然界的植物抗毒素，主要分布在虎杖、花生、葡萄、百合、桑葚等70余种植物中，近年来发现其具有抗菌、抗肿瘤、抗血栓、抗氧化、调节血脂、保护肝脏等多种有益于人体的生物学功能，成为人们关注的焦点，但其天然来源十分有限，且难溶于水,对光热敏感、化学性质不稳定,易被氧化分解,制约了其广泛应用。因此对其合成路线的研究、质量标准及制备成合适剂型以提高生物利用度就显的十分重要，本文以3,5-二甲氧基苯甲醇为原料，经过溴代、Arbuzov重排、wittig-horner缩合、脱甲基四步反应制备白藜芦醇，并根据05版药典规定及制备工艺建立相应的质量标准，针对其化学性质，将其制备成合适的纳米乳制剂并筛选出最佳处方。 |
回复此楼» 猜你喜欢
售SCI一区T0P文章，我:8.O.55.1.O54,科目全,可伽急
已经有5人回复
-
2026国自然函评费到账
已经有12人回复
-
跳槽后在研项目怎么办？
已经有8人回复
-
售SCI一区T0P文章，我:8.O55.1.O.54,科目全,可十急
已经有10人回复
-
售SCI一区T0P文章，我:8.O.55.1.O54,科目全,可伽急
已经有5人回复
-
售SCI一区文章，我:8O5.5.1.O5.4,科目全,可伽急
已经有4人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有7人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有5人回复
-
售SCI一区文章，我:8O5.5.1.O5.4,科目全,可伽急
已经有7人回复
-
售SCI一区T0P文章，我:8O.55.1.O.5.4,科目齐全,可+急
已经有6人回复
zhangzws
金虫 (正式写手)
- 翻译EPI: 41
- 应助: 0 (幼儿园)
- 金币: 1058.5
- 散金: 15
- 帖子: 355
- 在线: 115.3小时
- 虫号: 736112
- 注册: 2009-03-31
- 性别: GG
- 专业: 能源化工
10楼2010-08-02 18:58:34
zerohead
禁虫 (职业作家)
- 翻译EPI: 466
- 应助: 1 (幼儿园)
- 贵宾: 0.301
- 金币: 8727.8
- 散金: 850
- 红花: 15
- 沙发: 10
- 帖子: 3768
- 在线: 471.7小时
- 虫号: 1041741
- 注册: 2010-06-14
- 性别: GG
- 专业: 逻辑学
2楼2010-08-02 16:07:52
chzhbin
金虫 (职业作家)
- 翻译EPI: 2
- 应助: 20 (小学生)
- 贵宾: 1.356
- 金币: 1023.7
- 散金: 3832
- 红花: 40
- 沙发: 2
- 帖子: 3301
- 在线: 1673.9小时
- 虫号: 573652
- 注册: 2008-06-14
- 性别: GG
- 专业: 天然药物化学
3楼2010-08-02 16:48:37
zhangzws
金虫 (正式写手)
- 翻译EPI: 41
- 应助: 0 (幼儿园)
- 金币: 1058.5
- 散金: 15
- 帖子: 355
- 在线: 115.3小时
- 虫号: 736112
- 注册: 2009-03-31
- 性别: GG
- 专业: 能源化工
chzhbin(金币+26):非常感谢 呵呵 2010-08-02 17:06:10
| Abstract: Resveratrol (3,4’,5-trihydroxy-toluylene) as polyphenol compounds is a phytoalexin that mainly exists in 70 species of plants in nature which included polygonum cuspidatum, peanut, grape, lily, mulberry and other. Recently, the study found that resveratrol plays a physiological function in antibiotic, antitumor, antithrombotic, antioxidation, regulating blood lipid and the protection of the liver, which results that it becomes the focus of people's attention. However, the limited sources of natural resveratrol as well as its water-insoluble, optothermall-reactivity, poor chemical stability and oxidative decomposition restrict its application. So that the study of its synthetic method, quality standard and synthesis economical problem of crucial importance. In this paper, resveratrol is synthesized using 3,4-dimethoxy-phemethylolas raw material by bromination, Arbuzov rearrangement, wittig-horner condensation and demethylation. Based on the Chinese Pharmacopoeia (2005 edition) and preparation technology, the corresponding quality standards were built. In addition, based on its chemical properties, proper resveratrol nano-emulsion was prepared, and the optimal preparation process was screened out. |
4楼2010-08-02 16:56:43
40