²é¿´: 880  |  »Ø¸´: 3

sc-zsc

½ð³æ (СÓÐÃûÆø)

[½»Á÷] ¡¾ÇóÖú¡¿È·¶¨¿ØÖÆÒ»ÑÕÉ«ÐÔ×´µÄ»ùÒòÐÍ ÒÑÓÐ1È˲ÎÓë

ÏÖÔÚÓÐÁ½Ç×±¾£¨P1£ºÂÌÉ«£¬P2£ººÚÉ«£¬ÊýÁ¿×ã¹»¶àÇÒΪһÖÖ»ùÒòÐÍ£©£¬ÏÖÔÚÒª×öµÄÊÇͨ¹ýÕý·´½»¡¢ÔÓ½»¼°»Ø½»µÈÊֶκó´úµÄ±íÏÖÐÍÀ´ÍƲâÆäλÖ᪡ªÏ¸°ûÖÊ»òϸ°ûºË£¬²¢²»ÊÇÒª¾«È·µ½£Ä£Î£Á·Ö×ÓÉϵÄλÖá£ÁíÍ⣬»¹ÒªÄÜÍÆ²âÊǼ¸¶Ô»ùÒò¿ØÖƵġª¡ªÒ»¶Ô¡¢Á½¶Ô»ò¶à¶Ô¡£ËùÒÔ²»Óõ½·Ö×Ó·½Ã棬¾ÍÊÇÒÅ´«·½Ãæ¼òµ¥µÄÎÊÌâ¡£ ÎÒÔÚÕâ·½Ãæ¾ÍÒ»¡°²ËÄñ¡±£¬Ï£ÍûÄÜÓиßÊÖÖ¸µãһϣ¬»ò¸øµãÀàËÆ·½ÃæµÄ×ÊÁÏ¡£ÏÈÐÐл¹ý£¡×¢£º×îºÃµÄÖÁÉÙ10¸ö½ð±Ò£¬ÆäÓàµÄÊÓÇé¿ö¸ø¡£
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

» ±¾Ö÷ÌâÏà¹ØÉ̼ÒÍÆ¼ö: (ÎÒÒ²ÒªÔÚÕâÀïÍÆ¹ã)

» ±¾Ö÷ÌâÏà¹Ø¼ÛÖµÌùÍÆ¼ö£¬¶ÔÄúͬÑùÓаïÖú:

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

zwdbordeaux

ľ³æ (ÕýʽдÊÖ)

¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
seamuse(½ð±Ò+2,VIP+0):¸Ðл½»Á÷ÌÖÂÛ£¡ 12-28 20:59
sc-zsc(½ð±Ò+13,VIP+0):лл 1-8 08:02
ºÇºÇ£¬Õâ¸öÎÊÌâÓ¦¸ÃÊÇÒ»¸ö»ù´¡µÄÒÅ´«Ñ§·½ÃæµÄÎÊÌâ¡£ÎÒ¶ÔÒÅ´«ËäÈ»ÂÔ¶®Ò»¶þ£¬µ«ÊÇûÓоßÌåµÄʵ¼ù¾­Ñ飬ËùÒÔÔڴ˲»Ëµ×Ô¼ºµÄ¼û½â¡£
ÍÆ¼ö¸øÄãһƪÎÄÕ°ɣ¬ÊǹØÓÚÈýÎÄÓãÈâÑÕÉ«ÒÅ´«µÄ¡£ÈýÎÄÓãµÄÑÕÉ«ÓÐÁ½ÖÖºìÉ«ºÍ°×É«£¬È»ºóËûÃÇͨ¹ýÄãÌáµ½µÄ·½·¨£¬È·¶¨ÁËÓм¸¸ö»ùÒòλµãºÍ¼¸¸öµÈλ»ùÒò¿ØÖƵÄÎÊÌ⡣ϣÍû¶ÔÄãÓÐËù°ïÖú¡£
When Parameters in Dynamic Models Become Phenotypes: A Case Study on Flesh Pigmentation in the Chinook Salmon (Oncorhynchus tshawytscha)

http://www.genetics.org/cgi/content/full/179/2/1113

Äã¿ÉÒÔÏÈ¿´¿´ÕªÒª£¬Èç¹û¸ÐÐËȤ¿ÉÒÔ½Ó×Å¿´È«ÎÄ£º
The Pacific chinook salmon occurs as both white- and red-fleshed populations, with the flesh color type (red or white) seemingly under strong genetic influence. Previously published data on crosses between red- and white-fleshed individuals cannot be reconciled with a simple Mendelian two-locus, two-allele model, pointing to either a more complex inheritance pattern or the existence of gene interactions. Here we show that a standard single-locus, three-allele model can fully explain these data. Moreover, by implementing the single-locus model at the parameter level of a previously developed mathematical model describing carotenoid dynamics in salmon, we show that variation at a single gene involved in the muscle uptake of carotenoids is able to explain the available data. This illustrates how such a combined approach can generate biological understanding that would not be possible in a classical population genetic explanatory structure. An additional asset of this approach is that by allowing parameters to become phenotypes obeying a given genetic model, biological interpretations of mechanisms involved at a resolution level far beyond what is built into the original dynamic model are made possible. These insights can in turn be exploited in experimental studies as well as in construction of more detailed models.

[ Last edited by zwdbordeaux on 2009-12-28 at 20:35 ]
Truthcomesoutoferrormoreeasilythanoutofconfusion
2Â¥2009-12-28 20:32:06
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

whoiam21

Òø³æ (СÓÐÃûÆø)

¡ï ¡ï
seamuse(½ð±Ò+1,VIP+0):¸Ðл²ÎÓëÌÖÂÛ£¬»¶Ó­³£À´Àí¹¤Å©Áְ棡 12-29 19:55
sc-zsc(½ð±Ò+1,VIP+0):Ô­À´²»ÊÇÓиöÕý·´½»Â𣿠1-8 08:01
¾õµÃÈç¹ûÓÃÃϵ¶û¾­µäÒÅ´«Ñ§µÄ»°ÎÞ·¨È·¶¨µ¹µ×ÊÇÔÚȾɫÌ廹ÊÇϸ°ûÖʰɣ¿

ÊÇϰÌâ°É£¿¸Ð¾õ¿ÆÑÐÖв»¿ÉÄÜÓÐÕâÑùµÄÎÊÌâ
3Â¥2009-12-28 21:39:08
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

sc-zsc

½ð³æ (СÓÐÃûÆø)

ллÁË£¡
4Â¥2010-06-29 23:59:21
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
Ïà¹Ø°æ¿éÌø×ª ÎÒÒª¶©ÔÄÂ¥Ö÷ sc-zsc µÄÖ÷Ìâ¸üÐÂ
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] Ò»Ö¾Ô¸ÖÐÄÏ»¯Ñ§337Çóµ÷¼Á +4 niko- 2026-03-19 5/250 2026-03-20 13:49 by ´ÙÌì³É
[¿¼ÑÐ] 296Çóµ÷¼Á +4 www_q 2026-03-18 8/400 2026-03-20 12:12 by ѧԱ8dgXkO
[¿¼ÑÐ] 329Çóµ÷¼Á +6 ÏëÉÏѧ߹߹ 2026-03-19 6/300 2026-03-20 09:00 by ÿÌìÖ»°ÚһС»á
[¿¼ÑÐ] 0703»¯Ñ§µ÷¼Á +10 ÄÝÄÝninicgb 2026-03-15 14/700 2026-03-19 22:59 by ѧԱ8dgXkO
[¿¼ÑÐ] 288Çóµ÷¼Á +15 ÓÚº£º£º£º£ 2026-03-19 15/750 2026-03-19 22:41 by ѧԱ8dgXkO
[¿¼ÑÐ] 321Çóµ÷¼Á +8 ºÎÈó²É123 2026-03-18 10/500 2026-03-19 16:46 by ºÎÈó²É123
[¿¼ÑÐ] 346Çóµ÷¼Á[0856] +3 WayneLim327 2026-03-16 6/300 2026-03-19 11:21 by WayneLim327
[¿¼ÑÐ] 328Çóµ÷¼Á£¬Ó¢ÓïÁù¼¶551£¬ÓпÆÑо­Àú +4 ÉúÎ﹤³Ìµ÷¼Á 2026-03-16 12/600 2026-03-19 11:10 by ÉúÎ﹤³Ìµ÷¼Á
[¿¼ÑÐ] ±¾¿ÆÖ£ÖÝ´óѧÎïÀíѧԺ£¬Ò»Ö¾Ô¸»ª¿Æ070200ѧ˶£¬346Çóµ÷¼Á +4 ÎÒ²»ÊÇÒ»¸ù´Ð 2026-03-18 4/200 2026-03-19 09:11 by ¸¡ÔÆ166
[¿¼ÑÐ] 304Çóµ÷¼Á +6 ˾¿Õ. 2026-03-18 6/300 2026-03-18 23:03 by ÐÇ¿ÕÐÇÔÂ
[¿¼ÑÐ] ²ÄÁϹ¤³Ìר˶µ÷¼Á +5 204818@lcx 2026-03-17 6/300 2026-03-18 22:55 by 204818@lcx
[¿¼ÑÐ] ¡¾Í¬¼ÃÈí¼þ¡¿Èí¼þ£¨085405£©¿¼ÑÐÇóµ÷¼Á +3 2026eternal 2026-03-18 3/150 2026-03-18 19:09 by ²«»÷518
[¿¼ÑÐ] 08¹¤¿Æ 320×Ü·Ö Çóµ÷¼Á +5 À滨çóÍí·ç 2026-03-17 5/250 2026-03-18 14:49 by haxia
[¿¼ÑÐ] ÓÐûÓеÀÌú/ÍÁľµÄÏëµ÷¼ÁÄÏÁÖ£¬¸ø×Ô¼ºÕÐʦµÜÖС« +3 TqlXswl 2026-03-16 7/350 2026-03-17 15:23 by TqlXswl
[¿¼ÑÐ] 11408 Ò»Ö¾Ô¸Î÷µç£¬277·ÖÇóµ÷¼Á +3 zhouzhen654 2026-03-16 3/150 2026-03-17 07:03 by laoshidan
[¿¼ÑÐ] 333Çóµ÷¼Á +3 ÎÄ˼¿Í 2026-03-16 7/350 2026-03-16 18:21 by ÎÄ˼¿Í
[»ù½ðÉêÇë] ½ñÄêµÄ¹ú»ù½ðÊÇ´ò·ÖÖÆÂ𣿠50+3 zhanghaozhu 2026-03-14 3/150 2026-03-16 17:07 by ±±¾©À³ÒðÈóÉ«
[¿¼ÑÐ] 0703 ÎïÀí»¯Ñ§µ÷¼Á +3 ÎÒ¿ÉÒÔÉϰ¶µÄ¶Ô 2026-03-13 5/250 2026-03-16 10:50 by ÎÒ¿ÉÒÔÉϰ¶µÄ¶ÔÂ
[¿¼ÑÐ] 070305Çóµ÷¼Á +3 mlpqaz03 2026-03-14 4/200 2026-03-15 11:04 by peike
[¿¼ÑÐ] 330Çóµ÷¼Á +3 ?½´¸øµ÷¼Á¹òÁË 2026-03-13 3/150 2026-03-14 10:13 by JourneyLucky
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û