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弗吉尼亚大学杨杰课题组招聘博士后，博士生跟科研助理
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Research Overview: The Jie Yang Lab at the University of Virginia is currently recruiting postdocs, PhD students and research assistants to join our team. The Yang lab is dedicated to dissecting the molecular mechanisms of cellular stress response, specifically focusing on mitochondrial stress, endoplasmic reticulum (ER) stress, and downstream integrated stress response (ISR). we employ an interdisciplinary approach, integrating structural biology (Cryo-EM/Cryo-ET), biochemistry (protein characterization), and cell biology (fluorescent imaging). Our ultimate goal is to modulate those stress response pathways in physiological and pathological conditions, potentially leading to the development of novel therapeutics for related human diseases, including neurodegeneration, metabolic disorders, and cancer. In addition, we have established close collaborations with experts in disease-relevant mouse models to complement our mechanistic findings. Expected Candidates: We welcome applications from individuals interested in investigating the fundamental aspects of any significant biological processes. Ideal candidates should demonstrate self-motivation, a strong research interest, independence, good communication skills, and a collaborative mindset. Candidates with backgrounds and expertise in structural biology, molecular biology, biochemistry, or cell biology are preferred. highly motivated individuals with expertise in other fields are also encouraged to apply. Postdoc candidates should be well trained in leading projects, experimental design, troubleshooting, and scientific manuscripts writing. All positions are fully funded. Competitive salary and benefits will be provided. (postdoc: $70k/year + benefits, phd student: $38k/year + benefits) Dr. Jie Yang: Dr. Yang earned his B.S. degree in Life Sciences from Wuhan University. From 2014 to 2019, he pursued his Ph.D. in biophysics at Case Western Reserve University in Cleveland, USA, focusing on studying the molecular mechanisms of inflammasome activation and pyroptotic cell death in innate immunity. From 2019 to 2024, Dr. Yang performed his postdoctoral research at the Scripps Research Institute in San Diego, where he studied the molecular mechanisms of mitochondrial stress response. In August 2024, Dr. Yang establishes his independent research laboratory as a tenure-track assistant professor in the Department of Biochemistry and Molecular Genetics at the School of Medicine, University of Virginia. Dr. Yang’s prior research work can be found through google scholar: https://scholar.google.com/citat ... aaaj&hl=en. Or you can just google search with the following keywords: Jie Yang, Scripps Research. Recently, Dr. Yang has made exciting preliminary discoveries in the er stress pathway. The incoming postdoc or phd students will have the opportunity to take over those projects, which are likely to yield impactful publications within 1 year or so. Please feel free to reach out for more information about the projects and further discussion. The University of Virginia: Recognized as one of the top universities in the US, the University of Virginia is known as a member of the "public ivy". The University of Virginia consistently ranks among the top 30 best universities in the united states, holding the 24th position in the 2024 U.S. News ranking of the best universities overall, and the 3rd position in the 2022 U.S. News ranking of the best public universities. The School of Medicine hosts state-of-art facilities for conducting cutting-edge research, including a 300kv Titian Krios equipped with a K3 direct electron detector, a 200kv Glacios equipped with falcon4 direct electron detector, 200kv F20 and 120kv spirit screening microscopes, and an Aquilos 2 Cryo-FIB. we also have our own Vitrobot for freezing Cryo-EM grids efficiently. Living in Charlottesville: Charlottesville, a charming and inclusive town with a rich American history, offers a high quality of life highlighted by affordability, safety, family-friendly neighborhoods. Its convenient location near Washington D.C. and Richmond provides easy access to a wealth of tourist attractions, museums, and shopping malls. Outdoor enthusiasts can explore an abundance of hiking and biking trails amidst the breathtakingly beautiful blue ridge mountains. How to Apply: Please email a cover letter, CV, and contact information for 2-3 references to Dr. Yang at jieyang4080@gmail.com. |
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