24小时热门版块排行榜

返回列表

当前主题已经存档。

xutian32

金虫 (小有名气)

应助: 0 (幼儿园)
金币: 1131.8
帖子: 53
在线: 68.9小时
虫号: 531343
注册: 2008-03-23

[交流] 求助文章两篇

各位高手，有没有人可以帮忙下两篇文章啊，谢谢！题目是：Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents。和A single conserved proline residue determines the membrane topology of stomatin.

每篇文章悬赏金币5个！叩谢啦！

回复此楼

» 猜你喜欢

大龄残疾硕士的一点执念已经有14人回复
刑法学论文投稿求助已经有5人回复
今年E04面上已经有14人回复
Journal of Environmental Chemical Engineering 已经有3人回复
最后一年，祈求好运已经有3人回复
风电环氧领域已经有3人回复
2026年面上项目中了，2A+B, 会评顺利通过已经有8人回复
昨日死，今日生已经有8人回复
售T0P一区SCI文章，我:8O5.51.O.54,科目齐全,可＋急已经有4人回复
售T0P一区SCI文章，我:8O5.51.O.54,科目齐全,可＋急已经有4人回复

1楼 2009-09-16 11:25:56

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

695

木虫 (职业作家)

应助: 4 (幼儿园)
金币: 4528.5
散金: 126
红花: 5
帖子: 3149
在线: 394.1小时
虫号: 347369
注册: 2007-04-16
专业: 植物生理与生化

不用哦叩谢，爱莫能助啊

赞一下

回复此楼

2楼2009-09-16 15:19:19

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

guotieying

银虫 (正式写手)

应助: 1 (幼儿园)
金币: 269
红花: 6
帖子: 814
在线: 36.1小时
虫号: 518887
注册: 2008-03-05
专业: 作物种质资源与遗传育种学

★ ★ ★
amisking(金币+3,VIP+0): 9-16 20:23

Results from tissue microarray in this study and our previous reports revealed that stomatin-like protein 2 (SLP-2) is notably associated with tumorigenesis and metastasis. Many members of stomatin family are involved in tumor as mitochondrial component, and recent study has revealed that SLP-2 may also function in mitochondria. To further investigate the function of SLP-2, we used siRNA target SLP-2. Data showed that knock-down of SLP-2 potently inhibited cell motility, proliferation and slightly altered cell cycle without any significant change of apoptosis. Moreover, by combined application with different chemotherapeutic reagents, we observed the enhancement of cell chemosensitivity by SLP-2 depletion. We also confirmed that, SLP-2 localizes in mitochondria, affects mitochondrial membrane potential (MMP) and ATP production. We conclude that, SLP-2 is a mitochondrial protein and therefore, functions in energy process by MMP maintenance, and subsequently affecting cell motility, proliferation and chemosensitivity.

只找到了摘要，要出19个美元才能下载

赞一下(10人)

回复此楼

本来无一物，何处惹尘埃。