| 查看: 355 | 回复: 8 | |||
| 当前主题已经存档。 | |||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | |||
[交流]
求助文章两篇
|
|||
|
各位高手，有没有人可以帮忙下两篇文章啊，谢谢！题目是：Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents。和A single conserved proline residue determines the membrane topology of stomatin. 每篇文章悬赏金币5个！叩谢啦！  |
回复此楼» 猜你喜欢
284求调剂
已经有10人回复
-
一志愿山东大学药学学硕求调剂
已经有4人回复
-
07化学280分求调剂
已经有4人回复
-
298-一志愿中国农业大学-求调剂
已经有12人回复
-
求材料，环境专业调剂
已经有3人回复
-
335求调剂
已经有5人回复
-
求调剂
已经有7人回复
-
一志愿吉大化学322求调剂
已经有4人回复
-
环境学硕288求调剂
已经有8人回复
-
341求调剂(一志愿湖南大学070300)
已经有6人回复
7楼2009-09-16 23:33:49
695
木虫 (职业作家)
- 应助: 4 (幼儿园)
- 金币: 4528.5
- 散金: 126
- 红花: 5
- 帖子: 3149
- 在线: 394.1小时
- 虫号: 347369
- 注册: 2007-04-16
- 专业: 植物生理与生化
2楼2009-09-16 15:19:19
guotieying
银虫 (正式写手)
- 应助: 1 (幼儿园)
- 金币: 269
- 红花: 6
- 帖子: 814
- 在线: 36.1小时
- 虫号: 518887
- 注册: 2008-03-05
- 专业: 作物种质资源与遗传育种学
★ ★ ★
amisking(金币+3,VIP+0): 9-16 20:23
amisking(金币+3,VIP+0): 9-16 20:23
|
Results from tissue microarray in this study and our previous reports revealed that stomatin-like protein 2 (SLP-2) is notably associated with tumorigenesis and metastasis. Many members of stomatin family are involved in tumor as mitochondrial component, and recent study has revealed that SLP-2 may also function in mitochondria. To further investigate the function of SLP-2, we used siRNA target SLP-2. Data showed that knock-down of SLP-2 potently inhibited cell motility, proliferation and slightly altered cell cycle without any significant change of apoptosis. Moreover, by combined application with different chemotherapeutic reagents, we observed the enhancement of cell chemosensitivity by SLP-2 depletion. We also confirmed that, SLP-2 localizes in mitochondria, affects mitochondrial membrane potential (MMP) and ATP production. We conclude that, SLP-2 is a mitochondrial protein and therefore, functions in energy process by MMP maintenance, and subsequently affecting cell motility, proliferation and chemosensitivity. 只找到了摘要，要出19个美元才能下载 |
3楼2009-09-16 15:28:29
hound
金虫 (初入文坛)
- 应助: 0 (幼儿园)
- 金币: 1236.7
- 帖子: 28
- 在线: 30.7小时
- 虫号: 833404
- 注册: 2009-08-24
- 性别: GG
- 专业: 病原微生物变异与耐药
4楼2009-09-16 16:48:32
