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jw227

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´óÐÛºÃ(½ð±Ò+3,VIP+0):XIEXIE 9-10 09:07
the study of all nine system-related genes (AGT, CYP11B2, ACE, ACE2, AT1, AT2, MAS1, REN, RenBP) tag SNPs associated with essential hypertension is carried out in this project.

[ Last edited by jw227 on 2009-9-8 at 10:58 ]
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3Â¥2009-09-08 10:34:22
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jw227

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´óÐÛºÃ(½ð±Ò+5,VIP+0):XIEXIE 9-10 09:06
´óÐÛºÃ(½ð±Ò+1,VIP+0):лл 9-10 09:46
The research about mechanism of hypertension pathogenesis from the gene level is of important theoretical and clinical significance. but now, the related genes are limited in small groups, a small number of (single) gene in a small number of (single) sites, much lack of systemic. Thus,  intending to take full advantage of genetic resources of isolated population in Yunnan's minorities  and aiming at  one of the most important system in blood pressure regulation, renin - angiotensin - aldosterone system (RAAS),

[ Last edited by jw227 on 2009-9-8 at 10:57 ]
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2Â¥2009-09-08 10:30:30
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jw227

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´óÐÛºÃ(½ð±Ò+5,VIP+0):лл 9-10 09:08
´óÐÛºÃ(½ð±Ò+1,VIP+0):лл 9-10 09:46
The genotypes will be identified for every site. 9 haplotypes of genes will be established. The best combination mode of hypertension-related genes and its site in isolated population of Yunnan will be determined. The characteristic of blood pressure regulatory genes among nationalities with different genetic background will be explored. We will try our best to reveal the relevance of RAAS system and hypertension pathogenesis systematically and comprehensively ;  clarify the mechanism of essential hypertension pathogenesis ; provide theoretical basis for early diagnosis and risk assessment.

[ Last edited by jw227 on 2009-9-8 at 11:02 ]
ÎÒÊÇÀ´ÏûDzµÄ
4Â¥2009-09-08 10:48:40
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wyr2006

ľ³æ (ÖøÃûдÊÖ)

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´óÐÛºÃ(½ð±Ò+6,VIP+0):»¹ÊÇлл 9-10 09:47
To study the pathologic mechanism of hypertension on the genetic level has an important theoretical and clinical guiding significance. However, recent researches of hyptension related genes are restricted to small populations, less genes and loci, thus are lack of systematicness. In view of this, we are going to study the correlation between essential hypertension(EH) and tag SNPs in genes of the rennin-agiotensin-aldosterone system(RAAS), which plays a cardinal role in blood pressure regulation, by using the genetic resources of ....
5Â¥2009-09-10 09:44:21
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