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Reviewer #2: In this manuscript, authors report synthesis and crystal structures of new ferrocenyl nitroxides, and describe relationships between their structures and antioxidation activities.  These compounds and their physicochemical properties are interesting, but, the antioxidation activities should be examined,essentially, taking account for the toxicity of these compounds.  

This manuscript must be corrected and improved in many points listed below.  Authors should consider about these points, deeply, and must revise their manuscript, majorly.  


In Fig. 2, figure caption shows that ellipsoids of the ORTEP views are given at a 50 % probability level.  However, the shapes and sizes of atoms are different from those of refined structures.  Please see the checkCIF file of 4, showing the real ORTEP views at a 50 % probability level.  In Fig. 2, these atoms might be described with isotropic refinement parameters.  For exactly reporting these results, authors must take care of describing data details.  In this state, the manuscript does not meet the standard report in any journal.

Text p2,line 2
electrochemistry properties ----> electrochemical properties £¨ÎÒÒѾ­¸Ä³ÉÁËelectrochemical properties£©

Text p2, 2.2, 2nd paragraph, line 3
essentially geometrically ----> (should be corrected) £¨ÎÒÒѾ­¸ÄºÃÁË£©

Text p2, 2.2, 2nd paragraph, line 6
S-trans double system ----> ? £¨ÎÒÒѾ­¸ÄºÃÁË£©

Text p2, 2.2, 3rd paragraph, line 3
The intermolecular hydrogen bonds in 4b are not clearly shown in the sentences and Fig. 1.   £¨ÒѾ­¶Ô¾ä×Ó½øÐÐÁ˸ÄÕý£©

Text p3, 2.2, 3rd paragraph, line 8
The tortion angles within TEMPO are not clearly shown in the sentences.  The angle values shoud be checked, again.
C-C-C-N2 ----> C14-C15-C16-N2 ?
C-N2-C-C ----> C16-N2-C17-C18 and C17-N2-C16-C15 ?
O2-N2-C-C ----> O2-N2-C17-C18 and O2-N2-C16-C15  ?¡°
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