24小时热门版块排行榜

>论坛更新日志 (3741)
>虫友互识 (277)
>休闲灌水 (237)
>文献求助 (235)
>导师招生 (176)
>考博 (114)
>硕博家园 (104)
>基金申请 (83)
>论文投稿 (71)
>考研 (56)
>博后之家 (51)
>招聘信息布告栏 (39)
>公派出国 (38)
>教师之家 (26)
>论文道贺祈福 (25)
>找工作 (22)

返回列表

当前主题已经存档。

262402xiaoyu

铜虫 (小有名气)

应助: 0 (幼儿园)
金币: 2698.1
帖子: 176
在线: 19.6小时
虫号: 449958
注册: 2007-11-03
专业: 污染控制化学

[交流] （急）15金币问寡核苷酸链的非特异吸附和空间位阻问题

各位GGJJ ，今天在看一篇文献时（《Rigid carbon composites: a new transducing material for label-free electrochemical genosensing》）发现其中一段话“As can be seen from Fig. 4(A), with an increment of the IS200 target concentration, the guanine (a) and the adenine (b) signals increased up to 60 lg/ml. After this concentration, a slight reduction of the electrochemical signal was observed. This decrease in the signal, related
to higher quantities of DNA, can be explained either by steric hindrance or by non-specific self-association. Both effects compete with ssDNA adsorption on the transducer, thus decreasing the signal.”
请问一下This decrease in the signal, related to higher quantities of DNA, can be explained either by steric hindrance or by non-specific self-association. 中的steric hindrance 和non-specific self-association是什么意思啊 ? non-specific self-association的机理是什么呢？帮帮忙给予解答啦，最好能帮忙找点参考文献，谢谢大家