24小时热门版块排行榜

>论坛更新日志 (3280)
>虫友互识 (848)
>文献求助 (235)
>导师招生 (162)
>休闲灌水 (159)
>考博 (131)
>教师之家 (86)
>博后之家 (81)
>硕博家园 (80)
>找工作 (77)
>论文投稿 (75)
>论文道贺祈福 (67)
>基金申请 (65)
>考研 (57)
>公派出国 (51)
>招聘信息布告栏 (36)

返回列表

当前主题已经存档。

当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖

262402xiaoyu

铜虫 (小有名气)

应助: 0 (幼儿园)
金币: 2698.1
帖子: 176
在线: 19.6小时
虫号: 449958
注册: 2007-11-03
专业: 污染控制化学

[交流] （急）15金币问寡核苷酸链的非特异吸附和空间位阻问题

各位GGJJ ，今天在看一篇文献时（《Rigid carbon composites: a new transducing material for label-free electrochemical genosensing》）发现其中一段话“As can be seen from Fig. 4(A), with an increment of the IS200 target concentration, the guanine (a) and the adenine (b) signals increased up to 60 lg/ml. After this concentration, a slight reduction of the electrochemical signal was observed. This decrease in the signal, related
to higher quantities of DNA, can be explained either by steric hindrance or by non-specific self-association. Both effects compete with ssDNA adsorption on the transducer, thus decreasing the signal.”
请问一下This decrease in the signal, related to higher quantities of DNA, can be explained either by steric hindrance or by non-specific self-association. 中的steric hindrance 和non-specific self-association是什么意思啊 ? non-specific self-association的机理是什么呢？帮帮忙给予解答啦，最好能帮忙找点参考文献，谢谢大家

回复此楼

» 猜你喜欢

1楼 2009-05-09 15:31:18

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

liuhezhi

禁虫 (初入文坛)

★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★
262402xiaoyu(金币+15,VIP+0):谢谢啦 5-11 18:52

本帖内容被屏蔽

3楼2009-05-11 18:50:01

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

查看全部 3 个回答