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英国诺森比亚大学招收光电子博士生
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Project Description Earlier diagnostic/detection for diseases (cancer, chronic or foodborne) enables doctors making a rapid clinical decision, which considerably enhances the success of treatment and medical intervention and ultimately benefits to human health. Foodborne diseases have been a growing worldwide public health problem, which encompass a wide spectrum of illnesses, such as E-Coli, Salmonellosis, Listeriosis, and Gastroenteritis. To reduce the risk, high risk food products must be tested before being sold for consumption. The traditional technique for diseases earlier diagnostic is to culture diseases typically 1-2 days and then to do the test, which not only delays clinical decisions but also increases the cost. Hence, there is an urgent need to develop a high sensitivity, non-invasive biosensor for fast and early detection of diseases. The aim of this project is to develop a novel, high sensitivity, fast response and easy operating biosensor device that can manipulate and sense biomolecules, utilizing a fibre optic interferometry sensing technique integrated with multifunctional microfluidic systems. The hypotheses of this project is that a tapered microstructure singlemode-multimode-singlemode fibre structure can achieve very high refractive index sensitivity. By proper surface functionalisation on the sensor, it can be used to detect very low concentration biological analytes. As an example for the application of the developed biosensor, it will be demonstrated for detection, identification and quantification of foodborne pathogens with very high sensitivity (10 CFU/mL) and fast response (<2 hours). To achieve this goal, we propose to integrate the sensor with microfluidic system for sample manipulation, mixing, separation, concentration and detection, where our collaborator, Prof. Nicole Pamme in University of Hull has extensive experience in microfluidic systems. Academically strong candidates with BSc or Master’s Degree in Applied Physics or Optics or a closely related discipline are encouraged to apply. Experience in optoelectronics, optical fiber communications or optical sensing is desirable. The principal supervisor for this project is Qiang Wu. For further details of how to apply, entry requirements and the application form, see https://www.northumbria.ac.uk/re ... grees/how-to-apply/ Please note: Applications that do not include a research proposal of approximately 1,000 words (not a copy of the advert), or that do not include the advert reference (e.g. RDF19/EE/MPEE/WU) will not be considered. Deadline for applications: Friday 25 January 2019 Start Date: 1 October 2019 感兴趣的请务必登录网站递交申请。 |
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