| 查看: 867 | 回复: 7 | ||
| 【奖励】 本帖被评价4次，作者ltlipc增加金币 3.5 个 | ||
| 当前主题已经存档。 | ||
[资源]
Biomaterials关于介孔硅生物相容性的最新文章
|
||
|
很不错，推荐 2009年发表的文章，题目是2009The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors abstract如下： PorousSiisananostructuredmaterialthatisofinterestformolecularandcell-basedbiosensing,drug livery,andtissueengineeringapplications.Surfacechemistryisanimportantfactordeterminingthe stabilityofporousSiinaqueousmedia,itsafnityforvariousbiomolecularspecies,anditscompatibility withtissues.Inthisstudy,theattachmentandviabilityofaprimarycelltypetoporousSisamples containingvarioussurfacechemistriesisreported,andtheabilityoftheporousSilmstoretaintheir opticalreectivitypropertiesrelevanttomolecularbiosensingisassessed.Fourchemicalspeciesgrafted totheporousSisurfacearestudied:siliconoxide(viaozoneoxidation),dodecyl(viahydrosilylationwith dodecene),undecanoicacid(viahydrosilylationwithundecylenicacid),andoligo(ethylene)glycol(via hydrosilylationwithundecylenicacidfollowedbyanoligo(ethylene)glycolcouplingreaction).Fourier TransformInfrared(FTIR)spectroscopyandcontactanglemeasurementsareusedtocharacterizethe surface.Adhesionandshort-termviabilityofprimaryrathepatocytesonthesesurfaces,withand withoutpre-adsorptionofcollagentypeI,areassessedusingvitaldyes(calcein-AMandethidium homodimerI).Cellviabilityonundecanoicacid-terminatedporousSi,oxide-terminatedporousSi,and oxide-terminatedat(non-porous)Siaremonitoredbyquanticationofalbuminproductionoverthe courseof8days.ThestabilityofporousSithinlmsafter8daysincellcultureisprobedbymeasuring theopticalinterferometricreectancespectra.Resultsshowthathepatocytesadherebettertosurfaces coatedwithcollagen,andthatchemicalmodicationdoesnotexertadeleteriouseffectonprimaryrat hepatocytes.ThehydrosilylationchemistrygreatlyimprovesthestabilityofporousSiincontactwith culturedprimarycellswhileallowingcellcoveragelevelscomparabletostandardculturepreparations ontissueculturepolystyrene http://www.namipan.com/d/349befe80c8fd3c3224d3eb811589a9ae5157dc6f01b1d00 [ Last edited by ltlipc on 2008-12-19 at 21:01 ] |
回复此楼» 猜你喜欢
斑马鱼孵化求助
已经有0人回复
-
投稿Elsevier的Neoplasia杂志，到最后选publishing options时页面空白，不能完成投稿
已经有23人回复
-
生物力学与组织工程学论文润色/翻译怎么收费?
已经有122人回复
-
生物学-微生物学-博士申请，有分子生物学、发酵工程、生物信息学等基础
已经有1人回复
-
悉尼大学 AMME 机械工程 双ARC Future Fellows团队招收CSC博士生
已经有30人回复
-
2026 法国csc 个人渠道招聘。计算机/生物信息/evolution/network优先
已经有0人回复
-
蛋白条带歪
已经有1人回复
-
金属离子与化合物分子对接
已经有1人回复
-
求助参苓白术口服液、肥儿口服液，儿康宁糖浆的质量标准！
已经有2人回复
-
香港中文大学医学院 诚聘 研究助理教授 (医工结合/生物信息学方向)
已经有21人回复
2楼2009-03-10 12:26:06
3楼2009-03-10 14:19:48
4楼2009-03-10 14:49:08
6楼2009-05-04 16:41:33
8楼2009-09-29 21:18:13
简单回复
alexben5楼
2009-03-10 23:02
回复
顶一下！！
2009-09-29 19:31
回复
