应《网络安全法》要求，自2017年10月1日起，未进行实名认证将不得使用互联网跟帖服务。为保障您的帐号能够正常使用，请尽快对帐号进行手机号验证，感谢您的理解与支持！

24小时热门版块排行榜    

CyRhmU.jpeg
小木虫论坛-学术科研互动平台» 文献求助区» 检索知识 » 检索知识完结子版 » 帮我看看检索了没有
61/1返回列表
查看: 242  |  回复: 5
只看楼主@他人 存档 新回复提醒 (忽略) 收藏    在APP中查看
本帖产生 1 个 ，点击这里进行查看

yuguiyan

至尊木虫 (文坛精英)

[求助] 帮我看看检索了没有

14-3-3γ affects eIF5 to regulate β-casein synthesis in bovine mammary epithelial cells
回复此楼

» 猜你喜欢
1楼2017-02-09 16:50:48
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
回帖置顶 ( 共有1个 )

baiyuefei

版主 (文学泰斗)

风雪

优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主优秀版主优秀版主优秀版主

【答案】应助回帖

https://apps.webofknowledge.com/ ... age=1&doc=1
回复此楼
3楼2017-02-09 18:18:07
 已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
普通回帖

baiyuefei

版主 (文学泰斗)

风雪

优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主优秀版主文献杰出贡献优秀版主优秀版主优秀版主优秀版主优秀版主优秀版主

【答案】应助回帖

★ ★ ★ ★ ★
感谢参与，应助指数 +1
yuguiyan: 金币+5, ★★★★★最佳答案 2017-02-13 15:14:14
lazy锦溪: LS-EPI+1 2017-02-13 15:49:52
14-3-3 gamma affects eIF5 to regulate beta-casein synthesis in bovine mammary epithelial cells
作者:Yu, CP (Yu, Cuiping)[ 1,2 ] ; Luo, CC (Luo, Chaochao)[ 2 ] ; Gu, XY (Gu, Xinyu)[ 2 ] ; Zang, YL (Zang, Yanli)[ 2 ] ; Qu, B (Qu, Bo)[ 2 ] ; Khudhair, N (Khudhair, Nagam)[ 2 ] ; Li, QZ (Li, Qingzhang)[ 2 ] ; Gao, XJ (Gao, Xuejun)[ 2 ]
CANADIAN JOURNAL OF ANIMAL SCIENCE
卷: 96  期: 4  页: 478-487
DOI: 10.1139/cjas-2016-0038
出版年: DEC 2016
查看期刊信息
摘要
The 14-3-3 gamma protein participates in many biological processes; however, its regulatory mechanism in milk protein synthesis is not well studied. We hypothesized that 14-3-3 gamma might affect eIF5 (an initiation factor) to regulate beta-casein synthesis in dairy cows. In this study, a possible interaction between 14-3-3 gamma and eIF5 was investigated using bovine mammary epithelial cells (BMECs). The expression levels of 14-3-3 gamma and eIF5 in the mammary gland tissues from cows producing higher quality milk were higher than those from cows producing low-quality milk. Moreover, the expression of 14-3-3 gamma, eIF5, and beta-casein were increased at both mRNA and protein levels in BMECs cultured in vitro with methionine (Met) supplementation. Coimmunoprecipitation, colocalization, and FRET analysis further showed the evidences that 14-3-3 gamma physically bound to eIF5 in BMECs. Gene function studies revealed that 14-3-3 gamma positively regulated eIF5 through alteration of eIF2 alpha/p-eIF2 alpha ratio. Collectively, our data suggest that 14-3-3 gamma regulates beta-casein translation in BMECs through interaction with eIF5.
关键词
作者关键词:14-3-3 gamma; eIF5; eIF2 alpha; methionine; beta-casein synthesis; bovine mammary epithelial cells
KeyWords Plus:MILK PROTEIN-SYNTHESIS; DAIRY-COW; EUKARYOTIC TRANSLATION; PREINITIATION COMPLEX; SIGNALING PATHWAY; PROLIFERATION; PHOSPHORYLATION; EXPRESSION; LACTATION; PROMOTES
作者信息
通讯作者地址: Gao, XJ (通讯作者)
显示增强组织信息的名称        Northeast Agr Univ, Key Lab Agr Biol Funct Genes, Harbin 150030, Peoples R China.
地址:
显示增强组织信息的名称        [ 1 ] Dalian Polytech Univ, Natl Engn Res Ctr Seafood, Sch Food Sci & Technol, Dalian 116034, Peoples R China
显示增强组织信息的名称        [ 2 ] Northeast Agr Univ, Key Lab Agr Biol Funct Genes, Harbin 150030, Peoples R China
电子邮件地址:gaoxj5390@sina.com
基金资助致谢
基金资助机构        授权号
863 Project of Ministry of Science and Technology of China        
2013AA102504-03
Major State Basic Research Development Program of China (973 Program)        
2011CB100804
Doctoral Program of Dalian Polytechnic University        
61020705
查看基金资助信息   
出版商
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 65 AURIGA DR, SUITE 203, OTTAWA, ON K2E 7W6, CANADA
类别 / 分类
研究方向:Agriculture
Web of Science 类别:Agriculture, Dairy & Animal Science
文献信息
文献类型:Article
语种:English
入藏号: WOS:000388368200005
ISSN: 0008-3984
eISSN: 1918-1825
其他信息
IDS 号: EC8CP
Web of Science 核心合集中的 "引用的参考文献": 31
Web of Science 核心合集中的 "被引频次": 0
回复此楼
2楼2017-02-09 18:17:56
 已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

yuguiyan

至尊木虫 (文坛精英)
引用回帖:
2楼: Originally posted by baiyuefei at 2017-02-09 18:17:56
14-3-3 gamma affects eIF5 to regulate beta-casein synthesis in bovine mammary epithelial cells
作者:Yu, CP (Yu, Cuiping) ; Luo, CC (Luo, Chaochao) ; Gu, XY (Gu, Xinyu) ; Zang, YL (Zang, Yanli) ; Qu, ...

这是已经检索了是吧？
回复此楼
4楼2017-02-13 15:14:52
 已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

baiyuefei

版主 (文学泰斗)
引用回帖:
4楼: Originally posted by yuguiyan at 2017-02-13 15:14:52
这是已经检索了是吧？...

嗯
5楼2017-02-13 15:16:21
 已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

yuguiyan

至尊木虫 (文坛精英)
引用回帖:
5楼: Originally posted by baiyuefei at 2017-02-13 15:16:21
嗯

多谢
回复此楼
6楼2017-02-17 17:02:44
 已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 yuguiyan 的主题更新
61/1返回列表
普通表情 龙 兔 虎 猫
信息提示
关闭
请填处理意见
关闭