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Vivien_Wang

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虫号: 4073155
注册: 2015-09-15

[交流] 澳門大學健康科學學院Dr. Vivien Wang招聘博士生和博士後已有5人参与

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Ph.D. Student: MOP$12,500??
Postdoc: MOP$21,000??
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PhD Students & Postdoc
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Faculty of Health Sciences, University of Macau
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https://fhs.umac.mo
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vivienwang@umac.mo

Dr. Vivien Wang?????F?????????????????о??T?M?????P?о????????????????1??????NF-??B, I??B?? DNA?}?????X???w?Y??????2???о??@Щ????????????W???????W?е???????3?????????????????|????w?Y????

Dr. Vivien Wang????С?M?\???????W???Y??????W??????????????????W???g???о??????|???????{??C????M???U??会???W??????????о??I??????漰???D?????NF-??B???I??B?????|??????D??????????{???????????????T???棬????????????????L???????????c??????NF-??B?錧??????????·???N?C???{?????????PNF-??B???????α??{???????ǘO????????о??I??

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• ??????????????????/?????W?????P?I???????Wλ?????????????н??MOP$12,500 ??
• ??????????????????????P?I??????Wλ??????????????????|???_??????????X???w?W?????м??????B???????z?y???????????????W??????????????????зe?O??????B????????M???????????????????e?O???????Ъ????M???о?????????????r???ζ?N???????н?Q???}????????????F??????????????H????u??????l???^???P?????|?Y?????????W?????????????????f????????????????????W???????g????O???н??MOP$21,000 ??

The laboratory of Dr. Vivien Wang is currently recruiting both PhD students and Postdoctoral Fellow to conduct related projects. The major responsibilities include (1) X-ray structural study of NF-??B, I??B and DNA complexes; (2) biochemical and biological studies to provide greater functional understanding of these macromolecules; and (3) crystallization of other related proteins.

In this laboratory we use our knowledge and experience in the area of biochemistry, structural biology, cellular and molecular biology to study the functions and mechanisms of important molecules focusing on their biological functions. The major focus of the current research involves understanding the signal transduction mediated by the nuclear factor kappaB (NF-??B) and I??B proteins. The mammalian Rel/NF-??B family of transcription factors plays a critical role in diverse physiological processes including the immune response, inflammation, cell proliferation and survival. A wide variety of signals activate NF-??B driven gene expression through different NF-??B signaling pathways in a stimulus- and cell type-dependent manner. Due to the diverse regulatory mechanisms acting on NF-??B, the signal dependent activation of NF-??B remains a challenging area of research.

Applicants should have good communication skills in English.
• Ph.D. students applicants should have B.S. degree in Biology/Biochemistry or related field; have related wet-lab working experiences.
• Postdoc applicants should have a Ph.D. degree in biological sciences or related fields. Expertise in cloning, protein purification, and x-ray crystallography is a must. Experience with cell culture, cell assays, and other molecular biology techniques is a plus. Applicants should also have positive work attitude, good organization, and communication skills, and are highly motivated and self-initiated, capable of independently performing in-depth research, multi-tasking along with problem-solving expertise and good team player. Previous publications related to protein crystallography, biochemistry, etc. in international peer reviewed journals are a prerequisite. The postdoctoral fellow will also help maintain the lab and provide technical supports and supervisions to the graduate students.

Recent Publications:
Fusco, A.J., Mazumder, A., Wang, V.Y., Tao, Z., Ware, C., and Ghosh, G. Transient RelB-p100-NIK-IKK1 complex: a central intermediary in non-canonical NF-??B signaling. Sci Signal. 2016 (In press)

Sans??, M., Levin, RS., Lipp JJ, Wang, V.Y., Greifenberg, AK., Quezada, EM., Ali, A., Ghosh, A., Larochelle, S., Rana, TM., Geyer, M., Tong, L., Shokat, KM., Fisher, RP. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes Dev. 2016, 30(1), 117-131.

Wang, V.Y., Jiao, X., Kiledjian, M., and Tong, L. Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Res. 2015, 43(13), 6596-6606.

Wang, V.Y., Huang, W., Asagiri, M., Spann, N., Hoffmann, A., Glass, C., and Ghosh, G. The transcriptional specificity of NF-??B Dimers is coded within the ??B DNA Response elements. Cell Rep. 2012, 2(4), 824-839.

Ghosh, G., Wang, V.Y., Huang, D-B., and Fusco, A.J. NF-??B Regulation: Lessons from Structures. Immunological Rev. 2012, 246, 36-58.

??M???Dr. Vivien Wang ?????
Email: vivienwang@umac.mo; Tel: (+853) 8822 4933
Website: http://fhs.umac.mo/staff/academic-staff/vivien-ya-fan-wang/

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1楼 2016-08-25 17:37:41

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

geng14024

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小木虫: 金币+0.5, 给个红包，谢谢回帖

引用回帖:

2楼: Originally posted by iamliyang91 at 2016-08-26 00:04:12
老师您好，我是一名研三的学生，想了解一下贵实验室招博士的一些具体条件，比如：2017年澳大博士申请还可以用英语六级吗？贵实验室对候选人的毕业院校是否有限制？谢谢您！
...

可以用英语六级申请。本科毕业院校最好为双一流院校，或所在专业为双一流专业