| 查看: 6290 | 回复: 160 | ||||
| 【奖励】 本帖被评价130次，作者chemjade增加金币 103.6 个 | ||||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | ||||
[资源]
最新流出的药渡世界新药概览部分章节
|
||||
| 最近流出的药渡，世界新药概览2013卷，部分章节，抛砖引玉，希望能凑齐了。 |
回复此楼» 本帖附件资源列表
-
欢迎监督和反馈：小木虫仅提供交流平台，不对该内容负责。
本内容由用户自主发布，如果其内容涉及到知识产权问题，其责任在于用户本人，如对版权有异议，请联系邮箱：xiaomuchong@tal.com - 附件 1 : B-1-Acotiamide.pdf
2016-05-09 19:35:57, 9.25 M
» 收录本帖的淘帖专辑推荐
 药物申报与工艺设计 | 新药研发学习 |
» 本帖已获得的红花（最新10朵）
绿云行空» 猜你喜欢
26申博，活性成分递送以及乳液、乳凝胶包埋
已经有9人回复
-
微谱求助
已经有0人回复
-
药理学论文润色/翻译怎么收费?
已经有283人回复
-
数据驱动智能故障诊断技术应用与实践
已经有0人回复
-
基于AI智能算法的装备结构可靠性分析与优化设计技术
已经有0人回复
-
26在职申博—生物与医药—抗体/ADC药物方向，江浙沪，有项目，可带资。
已经有1人回复
-
求助求助
已经有0人回复
-
农业资源与环境、智慧农业专业本科生毕业论文课题选题求助
已经有1人回复
-
人工智能赋能聚合物及复合材料模型应用与实践
已经有0人回复
-
各国和国际组织现行药典注射用水质量标准
已经有0人回复
-
求助用微谱数据库查询
已经有0人回复
五星好评！！！好书好书-------
7楼2016-05-10 19:11:59
6楼2016-05-10 19:11:21
8楼2016-05-10 19:13:41
|
Acotiamide Hydrochloride Hydrate (Acofide®  Research code: Z-338 in Zeria; YM-443 in Astellas 1 General Information ● Acotiamide is a peripheral acetylcholinesterase (AChE) inhibitor and the first-in-class drug to treat functional dyspepsia (FD) in the world, which was approved in 2013 by PMDA of Japan. ● Acotiamide was originally discovered by Zeria, and co-developed with Astellas. The drug is co-marketing in Japan. ● Acotiamide prevents the hydrolysis of acetylcholine by inhibiting peripheral AChE which results in the enhancement of impaired gastric motility and consequently the improvement of FD symptoms. ● Acotiamide is indicated for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to FD. ● Available as tablets with each containing 100 mg of acotiamide and the recommended starting dose is one tablet three times daily before meals. Key Approvals around the World* Japan (PMDA) First approval date 03/25/2013 NDA NO. 22500AMX00868000 Brand name Acofide® Indication FD Authorisation holder Zeria/Astellas * Till May 2015, it had not been approved by FDA (US), EMA (EU) and CFDA (China). Worldwide Sales Note: The sale data of Acofide® was not available. Active Ingredient Molecular formula: C21H30N4O5S·HCl·3H2O Molecular weight: 541.06 CAS No.: 185106-16-5 (acotiamide) 773092-05-0 (acotiamide hydrochloride trihydrate) Chemical name: N-{2-[bis(1-methylethyl)amino]ethyl}- 2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino] thiazole-4- carboxamide monohydrochloride trihydrate Parameters of Lipinski's “Rule of 5” |
9楼2016-05-10 19:16:53
简单回复
2016-05-09 23:17
回复
五星好评 顶一下，感谢分享！
小北cc4楼
2016-05-10 08:32
回复
顶一下，感谢分享！
sypqingchun11楼
2016-05-10 23:27
回复
五星好评 顶一下，感谢分享！
xiaojie426412楼
2016-05-11 08:14
回复
五星好评 顶一下，感谢分享！
sjshvdc14楼
2016-05-11 08:21
回复
五星好评 顶一下，感谢分享！