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yyc12596

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[交流] SCI二审大修 这个周末要改出来了 已有28人参与

SCI二审大修,这个周末必须改出来。下周一去找导师审核。
   期盼着SCI能中。
   但是想到修改,只觉得愁得喘不动气。
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yyc12596

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大修(2) Answers: Thanks for your kind suggestions. We re-write the introduction part of genetic results as following: "Four HLH patients were identified with hemizygous or compound heterozygous mutations (Primary HLH group), included P2(compound heterozygote), P16(hemizygote), P17(hemizygote), and P26 (hemizygote). Forty-one HLH patients were categorized into Non-primary HLH group, included nine HLH patients were single heterozygotes(P1, P3, P4, P5, P6, P7, P10, P11, and P45), three HLH patients with only SNPs(P8, P9, and P38), and other 29 HLH patients with no mutations. The genetic findings of the 45 HLH patients were shown in Table 1, and figures of these mutations were shown in Figure S1, S2A, S2B, S3, S4, and S5. Except SNPs, all mutations were not found in controls."
10楼2016-02-27 21:37:51
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yyc12596

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Summary of mutations 换成Summary of genetic findings
5楼2016-02-27 18:06:08
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惊风00

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小木虫: 金币+0.5, 给个红包,谢谢回帖
一审大修,也在改,好头疼
13楼2016-02-27 21:48:21
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jiayoulongnv

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小木虫: 金币+0.5, 给个红包,谢谢回帖
一审大修在改,感觉也要愁死了。

发自小木虫Android客户端
24楼2016-02-29 12:48:04
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ilsdln

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加油,祝福
2楼2016-02-26 22:01:32
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yyc12596

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Major comments:
*(1) The presentation of the genetic results should be improved further. The nomenclature mutation, SNP, single heterozygous used by the authors is very confusing. Please rename the results section are "genetic results" and in table 1 use the term "Summary of genetic findings". It is not immediately clear from table 1 which one are real mutations and which one are polymorphisms or variants of unknown significance. Maybe the authors can reorganize the table to clarify that.
3楼2016-02-27 17:59:05
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yyc12596

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结果部分:Mutation Identification换成Genetic Results
4楼2016-02-27 18:01:10
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yyc12596

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Answers: Thanks for your kind suggestions. According to your advice, we replace the results section "Mutation Identification" with"Genetic Results", and rename the Table 1 title as" Summary of genetic findings in 45 HLH patients ".
6楼2016-02-27 18:14:48
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yyc12596

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In order to make the results of Table 1 more clear, we delete polymorphisms and variants of unknown significance, and only keep the real mutations.
7楼2016-02-27 18:25:36
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yyc12596

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大修*(2) The result section concerning the genetic results is also very confusing. Please introduce first the cases with a definitive molecular diagnosis, the four cases with biallelic PRF1 or hemizygous SH2D1A mutations. Then introduce the cases of patients with known HLH mutations only found in heterozygous state, such as P6 and P45. Then cases with monoallelic variants of unknown significance (rare, predicted damaging, but not reported before). Then cases with SNPs.

话说被审稿人这么一说,真觉得自己的稿子逻辑很差。
8楼2016-02-27 20:19:44
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yyc12596

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7个大修条目,10个小修条目。
现在坐在电脑前,只觉得昏昏欲睡。

赶紧改才是。
9楼2016-02-27 20:22:02
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