| 查看: 896 | 回复: 1 | |||
| 【悬赏金币】回答本帖问题，作者tangweiyang将赠送您 80 个金币 | |||
tangweiyang新虫 (小有名气)
|
[求助]
稿件大修，审稿人提出的几个问题不好解决，求助各位大神
|
||
|
Reviewer #2: Please revise well the following comments and queries and answer to determine validity of this research 9- Absorption capacity of polymers section ……….. The analyzed concentrations (150 <mu>g/mL) of both THP and CHA reveal very bad sensitivity of the chromatographic procedure also there is no pointing at limits of detection and quantitation for the analytes by the chromatographic method. Do the starting concentrations for calibration ranges are the LOQ values? 16- Validation of SPE-HPLC method section …….. The mentioned linearity range (1 - 100 <mu>g/mL) indicates low sensitivity of the chromatographic method which is not compatible with analysis biological samples（没看懂，怎么解决） 17- Regression equations for both drugs show huge slopes (63143 and 27096) indicating that the regression line is nearly perpendicular to the x-axis which is not accepted……… The very large values of intercepts confirm that the chromatographic analytical method extremely lacks selectivity ……… How did you construct the calibration curves and for how many points? At which matrix did you construct calibration curves? Why didn't you explore figures for calibration curves of the analytes?（本人疑问：难道标准曲线截距大小有规定？） 20- Figure (9) ……. You mentioned that the mobile phase system is methanol/water/acetic acid (20/80/0.4, v/v/v) …….Didn't you mention before that Acetic acid is added as 0.4 % of the total system, so it is wrong to write it in this manner. |
回复此楼» 猜你喜欢
复试调剂，一志愿南农083200食品科学与工程
已经有4人回复
-
一志愿太原理工安全工程300分，求调剂
已经有3人回复
-
284求调剂
已经有11人回复
-
食品工程专硕求调剂
已经有3人回复
-
324求调剂
已经有7人回复
-
一志愿武汉理工，总分321，英一数二，求老师收留。
已经有4人回复
-
287求调剂
已经有7人回复
-
325求调剂
已经有5人回复
-
343求调剂
已经有4人回复
-
求调剂推荐 材料 304
已经有4人回复
gaoyuling
铜虫 (正式写手)
- 应助: 0 (幼儿园)
- 金币: 1314.5
- 红花: 2
- 帖子: 384
- 在线: 46.4小时
- 虫号: 594516
- 注册: 2008-09-06
- 性别: MM
- 专业: 色谱分析
2楼2017-07-29 14:20:03
6