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Systems Biology：The Challenge of Complexity
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 Biological signaling pathways dynamically interact with one another to form complex information networks intracellularly, intercellularly, and eventually at the level of the organism. Biology and medicine have conventionally focused on identification and characterization of functional elements in biological signaling pathways. Recently, research in this field has been pursuing a new approach, systems biology, to understand the dynamics, complexity, and physiological functions of the biological signaling networks. Instead of reductionistic analyses or large-scale studies of biomolecules piece by piece, systems biology emphasizes the need for interdisciplinary methods and analysis of the regulation and operation of information networks at the systems level. The Uehara Memorial Symposium 2008, entitled “Systems Biology: The Challenge of Complexity,” was convened in Tokyo from June 30 to July 2, 2008. The aim of the symposium was to bring together leading scientists in the field of systems biology to discuss the latest research on function and dysfunction of biological networks. The following are the main topics addressed in the symposium: 1. Dynamics and complexity of intercellular networks 2. Integrative mechanism of intracellular information networks 3. Dysfunction of information networks and related diseases An explicit aim of the symposium was to contribute to an understanding of the complexity and dynamics of biological systems and to direct our efforts toward the development of novel strategies for disease control. We are very pleased to be able to publish the proceedings of this exciting symposium. Osaka, Japan Shigetada Nakanishi, Editor |
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2015-10-02 20:48:46, 17.97 M
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