| 查看: 1685 | 回复: 31 | |||
[交流]
色谱B投稿交流
|
|||
|
外审完后判定大修，各位帮我看看，有希望吗 Comments: Dear Dr. Xueying, Thank you for submitting your manuscript to J. Chrom. B. Based on the received referee report I request a major revision of your manuscript. There are notably important parameters of your study that should be clarified according to current regulatory guidelines. Please address all comments and submit a revised version of your study for further review. Sincerely yours, Rainer Bischoff Editor in Chief Reviewer #1: The article is interesting and revision is required in improving the method development and validation as per USFDA JULY 2015 recommendation for method validation of drugs and biologic. Please find the queries as enlisted (i) Method robustness needs to be evaluated and discussed in method development (ii) Comparative and contrasting model of bio-distribution has not been cited . A reference model is required to be incorporated so that the study findings are anchored to the extant knowledge domain (iii) Need to provide statistical methods to confirm matrix effect in different lots have no impact on method. Statistical support as per USFDA JULY 2015 recommendation for method validation of drugs and biologic clearly states for such confirmatory analysis. (iv) Figures with T-joint to show there is no ion suppression or enhancement at the retention time of analyte is important and should be essentially discussed. (v) Metabolites monitoring needs to be discussed. (vi) Discussion on using ESI mode of mass spectrometry, employing liquid -liquid chromatography and reason for selecting Inertsil ®ODS3 C18 column for separation has not been clarified. (vii) Syntax errror and English usage needs to be improved throughout the paper. (viii) Authors should argue the potential of being a high-throughput method due to achieving separation from both endogenous and exogenous interfering compounds. (ix) Quality of method should be discussion with clarity against the reported literature. (x) However, considering the merit of the research highlights, the article has a potential to fit in short communication category after revision. Though the article couldn't be accepted in current form, it is suggested that authors work on the major points as discussed above and resubmit for consideration. Once again, thanking you for contributing in bio-distribution field and best wishes for your future endeavors. |
回复此楼» 猜你喜欢
今天基金会出结果吗？20260819
已经有16人回复
-
科研孤儿太难了
已经有16人回复
-
filecode=后面第一个是大写字母
已经有13人回复
-
我面上完蛋了
已经有6人回复
-
应该是下周三26日公布了吧？
已经有4人回复
-
投稿咨询
已经有7人回复
-
今天放榜没戏了吧
已经有11人回复
-
让我中一个面上吧！
已经有12人回复
-
基金啊基金
已经有4人回复
-
放榜前的不淡定
已经有13人回复
» 本主题相关价值贴推荐，对您同样有帮助:
- 消除催化零回复，感谢虫友来交流(七）
已经有16人回复
- 【2015-1-31】第十五届分析化学中的化学计量学会议通知（CAC-2015）
已经有112人回复
- 谢沐风在同写意27期活动的报告记要
已经有35人回复
- 【2012-10-26】中国化学会第十一届全国分析化学年会第一轮会议通知
已经有65人回复
- 晶体可以发表的杂志（应该没发过）
已经有7人回复
- 投稿交流
已经有2人回复
- 【交流】zz《分析化学》2011年“仪器专刊”征稿启事
已经有0人回复
- SCI投稿指南
已经有8人回复
» 抢金币啦！回帖就可以得到:
-
散金祈福
+5/4170
-
每年这时候我都再仔细读一遍《范进中举》
+1/482
-
上海交通大学张航课题组招聘博士后（电化学储能）
+1/91
-
强耀生物金秋开学季活动，2026年8月18日-10月31日，肽库筛选低至2W5
+3/91
-
山东征女友，坐标济南
+1/91
-
基金焦虑，发个帖子，缓解一下
+2/72
-
上海交通大学张航课题组招聘博士后（电化学能量存储与转换）
+1/44
-
流放岭南浮肿了求救
+1/40
-
武汉，诚征男友，不异地，年龄大了
+1/32
-
中科院大连化学物理研究所 招聘 催化剂研发方向 科研助理 2名
+1/14
-
南京大学 智能驱动与感知材料实验室 诚招申请考核博士生/科研助理/博士后
+1/14
-
pcold 原核表达载体
+1/11
-
2027环境工程博士申请
+1/9
-
中国科学院生态环境研究中心环境工程相关方向招收保送硕士和联合培养博士和硕士研究生
+1/4
-
南京医科大学-冯璋课题组-招收2027级生化与分子生物学专业博士和硕士研究生
+1/3
-
北理工集成电路杰青团队 | 诚招科助理
+1/2
-
出全新蔡司 Plan?APOCHROMAT 20×/0.8 平场复消色差物镜
+1/2
-
找女友
+1/2
-
新审查指南施行半年，AI方向的专利申请是不是更看"技术味"了？
+1/2
-
【产品测评分享】体外转录产量不理想、dsRNA 副产物高？T7 RNA 聚合酶实测体验
+1/1
2楼2015-08-21 12:30:55
9楼2015-08-21 13:24:22
11楼2015-08-21 13:41:59
简单回复
石头阿呆3楼
2015-08-21 12:46
回复
wtpierce(金币+1): 谢谢参与
..
211001124楼
2015-08-21 12:51
回复
wtpierce(金币+1): 谢谢参与
2015-08-21 12:55
回复
wtpierce(金币+1): 谢谢参与
!
dmbb6楼
2015-08-21 12:57
回复
wtpierce(金币+1): 谢谢参与
2015-08-21 12:58
回复
wtpierce(金币+1): 谢谢参与
clszdy8楼
2015-08-21 13:23
回复
wtpierce(金币+1): 谢谢参与
litzmath10楼
2015-08-21 13:33
回复
wtpierce(金币+1): 谢谢参与
hydzp12楼
2015-08-21 13:43
回复
wtpierce(金币+1): 谢谢参与
a
ZloveA13楼
2015-08-21 13:56
回复
wtpierce(金币+1): 谢谢参与
祝福
shinyzd14楼
2015-08-21 13:56
回复
wtpierce(金币+1): 谢谢参与
支持
deweini15楼
2015-08-21 14:01
回复
wtpierce(金币+1): 谢谢参与
xiejf16楼
2015-08-21 14:09
回复
wtpierce(金币+1): 谢谢参与
一
miaojiabing17楼
2015-08-21 14:23
回复
wtpierce(金币+1): 谢谢参与
gltsycw18楼
2015-08-21 14:25
回复
wtpierce(金币+1): 谢谢参与
gltsycw19楼
2015-08-21 14:28
回复
hyena.20楼
2015-08-21 14:38
回复
wtpierce(金币+1): 谢谢参与
天涯201221楼
2015-08-21 14:38
回复
wtpierce(金币+1): 谢谢参与
xiaomaya204622楼
2015-08-21 14:41
回复
wtpierce(金币+1): 谢谢参与
laom201323楼
2015-08-21 14:43
回复
wtpierce(金币+1): 谢谢参与
小虫199224楼
2015-08-21 14:43
回复
wtpierce(金币+1): 谢谢参与
sz_kebaoyuan25楼
2015-08-21 14:45
回复
wtpierce(金币+1): 谢谢参与
小蚂蚁199726楼
2015-08-21 14:47
回复
wtpierce(金币+1): 谢谢参与
tingting198227楼
2015-08-21 14:50
回复
wtpierce(金币+1): 谢谢参与
小蚂蚁199828楼
2015-08-21 14:53
回复
wtpierce(金币+1): 谢谢参与
jixiangbao29楼
2015-08-21 14:56
回复
wtpierce(金币+1): 谢谢参与
wdxmu30楼
2015-08-21 15:00
回复
wtpierce(金币+1): 谢谢参与
。 [ 发自手机版 https://muchong.com/3g ]
交大狂人31楼
2015-08-21 15:05
回复
wtpierce(金币+1): 谢谢参与
00
假大空32楼
2015-08-21 15:16
回复
wtpierce(金币+1): 谢谢参与
