| 查看: 1705 | 回复: 31 | |||
[交流]
色谱B投稿交流
|
|||
|
外审完后判定大修，各位帮我看看，有希望吗 Comments: Dear Dr. Xueying, Thank you for submitting your manuscript to J. Chrom. B. Based on the received referee report I request a major revision of your manuscript. There are notably important parameters of your study that should be clarified according to current regulatory guidelines. Please address all comments and submit a revised version of your study for further review. Sincerely yours, Rainer Bischoff Editor in Chief Reviewer #1: The article is interesting and revision is required in improving the method development and validation as per USFDA JULY 2015 recommendation for method validation of drugs and biologic. Please find the queries as enlisted (i) Method robustness needs to be evaluated and discussed in method development (ii) Comparative and contrasting model of bio-distribution has not been cited . A reference model is required to be incorporated so that the study findings are anchored to the extant knowledge domain (iii) Need to provide statistical methods to confirm matrix effect in different lots have no impact on method. Statistical support as per USFDA JULY 2015 recommendation for method validation of drugs and biologic clearly states for such confirmatory analysis. (iv) Figures with T-joint to show there is no ion suppression or enhancement at the retention time of analyte is important and should be essentially discussed. (v) Metabolites monitoring needs to be discussed. (vi) Discussion on using ESI mode of mass spectrometry, employing liquid -liquid chromatography and reason for selecting Inertsil ®ODS3 C18 column for separation has not been clarified. (vii) Syntax errror and English usage needs to be improved throughout the paper. (viii) Authors should argue the potential of being a high-throughput method due to achieving separation from both endogenous and exogenous interfering compounds. (ix) Quality of method should be discussion with clarity against the reported literature. (x) However, considering the merit of the research highlights, the article has a potential to fit in short communication category after revision. Though the article couldn't be accepted in current form, it is suggested that authors work on the major points as discussed above and resubmit for consideration. Once again, thanking you for contributing in bio-distribution field and best wishes for your future endeavors. |
回复此楼» 猜你喜欢
国社科系统bug了，是不是要放榜了？
已经有9人回复
-
申博发邮件
已经有9人回复
-
各位大神，目前国内有哪些比较好用的逆合成软件？
已经有9人回复
-
上海工程技术大学激光智能制造课题组｜2027级博士研究生招生公告
已经有8人回复
-
上海工程技术大学激光智能制造课题组招收博士研究生
已经有8人回复
» 本主题相关价值贴推荐，对您同样有帮助:
- 消除催化零回复，感谢虫友来交流(七）
已经有16人回复
- 【2015-1-31】第十五届分析化学中的化学计量学会议通知（CAC-2015）
已经有112人回复
- 谢沐风在同写意27期活动的报告记要
已经有35人回复
- 【2012-10-26】中国化学会第十一届全国分析化学年会第一轮会议通知
已经有65人回复
- 晶体可以发表的杂志（应该没发过）
已经有7人回复
- 投稿交流
已经有2人回复
- 【交流】zz《分析化学》2011年“仪器专刊”征稿启事
已经有0人回复
- SCI投稿指南
已经有8人回复
2楼2015-08-21 12:30:55
9楼2015-08-21 13:24:22
11楼2015-08-21 13:41:59
简单回复
石头阿呆3楼
2015-08-21 12:46
回复
wtpierce(金币+1): 谢谢参与
..
211001124楼
2015-08-21 12:51
回复
wtpierce(金币+1): 谢谢参与
2015-08-21 12:55
回复
wtpierce(金币+1): 谢谢参与
!
dmbb6楼
2015-08-21 12:57
回复
wtpierce(金币+1): 谢谢参与
2015-08-21 12:58
回复
wtpierce(金币+1): 谢谢参与
clszdy8楼
2015-08-21 13:23
回复
wtpierce(金币+1): 谢谢参与
litzmath10楼
2015-08-21 13:33
回复
wtpierce(金币+1): 谢谢参与
hydzp12楼
2015-08-21 13:43
回复
wtpierce(金币+1): 谢谢参与
a
ZloveA13楼
2015-08-21 13:56
回复
wtpierce(金币+1): 谢谢参与
祝福
shinyzd14楼
2015-08-21 13:56
回复
wtpierce(金币+1): 谢谢参与
支持
deweini15楼
2015-08-21 14:01
回复
wtpierce(金币+1): 谢谢参与
xiejf16楼
2015-08-21 14:09
回复
wtpierce(金币+1): 谢谢参与
一
miaojiabing17楼
2015-08-21 14:23
回复
wtpierce(金币+1): 谢谢参与
gltsycw18楼
2015-08-21 14:25
回复
wtpierce(金币+1): 谢谢参与
gltsycw19楼
2015-08-21 14:28
回复
hyena.20楼
2015-08-21 14:38
回复
wtpierce(金币+1): 谢谢参与
天涯201221楼
2015-08-21 14:38
回复
wtpierce(金币+1): 谢谢参与
xiaomaya204622楼
2015-08-21 14:41
回复
wtpierce(金币+1): 谢谢参与
laom201323楼
2015-08-21 14:43
回复
wtpierce(金币+1): 谢谢参与
小虫199224楼
2015-08-21 14:43
回复
wtpierce(金币+1): 谢谢参与
sz_kebaoyuan25楼
2015-08-21 14:45
回复
wtpierce(金币+1): 谢谢参与
小蚂蚁199726楼
2015-08-21 14:47
回复
wtpierce(金币+1): 谢谢参与
tingting198227楼
2015-08-21 14:50
回复
wtpierce(金币+1): 谢谢参与
小蚂蚁199828楼
2015-08-21 14:53
回复
wtpierce(金币+1): 谢谢参与
jixiangbao29楼
2015-08-21 14:56
回复
wtpierce(金币+1): 谢谢参与
wdxmu30楼
2015-08-21 15:00
回复
wtpierce(金币+1): 谢谢参与
。 [ 发自手机版 https://muchong.com/3g ]
交大狂人31楼
2015-08-21 15:05
回复
wtpierce(金币+1): 谢谢参与
00
假大空32楼
2015-08-21 15:16
回复
wtpierce(金币+1): 谢谢参与