24小时热门版块排行榜    

北京石油化工学院2026年研究生招生接收调剂公告
查看: 551  |  回复: 6
当前主题已经存档。
当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖

wuselht

铁杆木虫 (正式写手)

[交流] 请问这里最后一个单词base是什么意思?

Sucinimidyl esters are used, inter alia, as activated acyl derivatives, in particular when other acylating agents, such as acid chlorides or anhydrides, cannot be employed on account of the lability of startingmaterials or final products. This applies particularly in the field of peptide chemistry. For coupling a covalent peptide bond, an activated carboxyl component is necessary. The previously most frequently used method for carboxyl activation is basedon the formation of succinimidyl esters by reaction of the corresponding carboxylic acid with carbodiimides, such as, for example, N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide. The disadvantage in this process lies, on the one hand, inthe coupling reagent DCC on account of its allergenicity and of the high price, and, on the other hand, in the by-product N,N'-dicyclohexylurea obtained here, which firstly contaminates the succinimidyl ester and secondly has to be disposed of. For these reasons, it was attempted to replace the system DCC/N-hydroxysuccinimide. Possible alternatives are systems of the type halophosphoric acid ester/N-hydroxysuccinimide/base.[/size]就是这里最后一个base,是啥意思?我不是学生物的为了有语境,把全部一段都写了,网上搜的一段专利文献,留下来我也好找得到
http://www.patentgenius.com/patent/5929251.html
回复此楼

» 猜你喜欢

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

qfzhang

银虫 (小有名气)


xyklmu(金币+1,VIP+0):感谢答复
N-羟基琥珀酰亚胺 nhs,刚才Google了一下,补充
4楼2008-08-19 13:57:43
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
查看全部 7 个回答

wuselht

铁杆木虫 (正式写手)

谢谢回复,还不是很清楚,烦请继续指点

顶上去如果是碱的话,能帮忙明确一下,指的是什么碱呢?
N-甲基马啡啉怎样?
马上评分
2楼2008-08-19 11:21:26
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

qfzhang

银虫 (小有名气)


wuselht(金币+1,VIP+0):谢谢
一种合成偶联经常用到的试剂,琥珀酰胺,简称nhs, 一般和edc配合使用,edc是碳二亚胺
3楼2008-08-19 13:54:01
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

wuselht

铁杆木虫 (正式写手)

N-hydroxysuccinimide/base.
楼上的说的是前面那个N-hydroxysuccinimide吧,我问的是后面的base
5楼2008-08-19 21:53:14
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 285求调剂 +3 AZMK 2026-03-27 5/250 2026-03-27 18:09 by AZMK
[考研] 277跪求调剂 +4 1915668 2026-03-27 7/350 2026-03-27 16:03 by 1915668
[考研] 材料292调剂 +12 橘颂思美人 2026-03-23 12/600 2026-03-27 15:44 by caszguilin
[考研] 339求调剂 +4 烤麦芽 2026-03-27 5/250 2026-03-27 13:23 by 752105528
[考研] 316求调剂 +5 Pigcasso 2026-03-24 5/250 2026-03-27 12:10 by zhshch
[考研] 0703化学/290求调剂/本科经历丰富/工科也可 +7 丹青奶盖 2026-03-26 8/400 2026-03-27 11:24 by 丹青奶盖
[考研] 081200-11408-276学硕求调剂 +4 崔wj 2026-03-26 4/200 2026-03-27 08:04 by chemisry
[考研] 327求调剂 +7 prayer13 2026-03-23 7/350 2026-03-26 20:48 by 不吃魚的貓
[考研] 324求调剂 +4 wysyjs25 2026-03-21 4/200 2026-03-26 20:38 by fmesaito
[考研] 总分322求生物学/生化与分子/生物信息学相关调剂 +5 星沉uu 2026-03-26 6/300 2026-03-26 19:02 by macy2011
[考研] 机械学硕310分,数一英一,一志愿211本科双非找调剂信息 +3 @357 2026-03-25 3/150 2026-03-26 16:34 by by.MENG
[考研] 281求调剂 +6 Koxui 2026-03-24 7/350 2026-03-26 15:37 by 无际的草原
[考研] 总分293求调剂 +6 加一一九 2026-03-25 8/400 2026-03-26 13:30 by yujianx
[考研] 309求调剂 +4 gajsj 2026-03-25 5/250 2026-03-26 00:27 by Dyhoer
[考研] 材料与化工328分调剂 +6 。,。,。,。i 2026-03-23 6/300 2026-03-25 22:30 by 418490947
[考研] 334分 一志愿武理-080500 材料求调剂 +4 李李不服输 2026-03-25 4/200 2026-03-25 21:26 by 星空星月
[考研] 0854电子信息求调剂 324 +4 Promise-jyl 2026-03-23 4/200 2026-03-25 11:36 by Sugarlight
[考研] 求调剂一志愿武汉理工大学材料工程(085601) +5 WW.' 2026-03-23 7/350 2026-03-24 14:50 by sprinining
[考研] 335求调剂 +4 yuyu宇 2026-03-23 5/250 2026-03-23 23:49 by Txy@872106
[考研] 求调剂 +7 十三加油 2026-03-21 7/350 2026-03-23 23:48 by 热情沙漠
信息提示
请填处理意见