±±¾©Ê¯ÓÍ»¯¹¤Ñ§Ôº2026ÄêÑо¿ÉúÕÐÉú½ÓÊÕµ÷¼Á¹«¸æ
²é¿´: 552  |  »Ø¸´: 6
µ±Ç°Ö÷ÌâÒѾ­´æµµ¡£
µ±Ç°Ö»ÏÔʾÂú×ãÖ¸¶¨Ìõ¼þµÄ»ØÌû£¬µã»÷ÕâÀï²é¿´±¾»°ÌâµÄËùÓлØÌû

wuselht

Ìú¸Ëľ³æ (ÕýʽдÊÖ)

[½»Á÷] ÇëÎÊÕâÀï×îºóÒ»¸öµ¥´ÊbaseÊÇʲôÒâ˼£¿

Sucinimidyl esters are used, inter alia, as activated acyl derivatives, in particular when other acylating agents, such as acid chlorides or anhydrides, cannot be employed on account of the lability of startingmaterials or final products. This applies particularly in the field of peptide chemistry. For coupling a covalent peptide bond, an activated carboxyl component is necessary. The previously most frequently used method for carboxyl activation is basedon the formation of succinimidyl esters by reaction of the corresponding carboxylic acid with carbodiimides, such as, for example, N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide. The disadvantage in this process lies, on the one hand, inthe coupling reagent DCC on account of its allergenicity and of the high price, and, on the other hand, in the by-product N,N'-dicyclohexylurea obtained here, which firstly contaminates the succinimidyl ester and secondly has to be disposed of. For these reasons, it was attempted to replace the system DCC/N-hydroxysuccinimide. Possible alternatives are systems of the type halophosphoric acid ester/N-hydroxysuccinimide/base.[/size]¾ÍÊÇÕâÀï×îºóÒ»¸öbase£¬ÊÇɶÒâ˼£¿ÎÒ²»ÊÇѧÉúÎïµÄΪÁËÓÐÓï¾³£¬°ÑÈ«²¿Ò»¶Î¶¼Ð´ÁË£¬ÍøÉÏËѵÄÒ»¶ÎרÀûÎÄÏ×£¬ÁôÏÂÀ´ÎÒÒ²ºÃÕҵõ½
http://www.patentgenius.com/patent/5929251.html
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

qfzhang

Òø³æ (СÓÐÃûÆø)

¡ï
wuselht(½ð±Ò+1,VIP+0):лл
Ò»ÖֺϳÉżÁª¾­³£Óõ½µÄÊÔ¼Á£¬çúçêõ£°·£¬¼ò³Ænhs£¬ Ò»°ãºÍedcÅäºÏʹÓã¬edcÊÇ̼¶þÑǰ·
3Â¥2008-08-19 13:54:01
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
²é¿´È«²¿ 7 ¸ö»Ø´ð

wuselht

Ìú¸Ëľ³æ (ÕýʽдÊÖ)

лл»Ø¸´£¬»¹²»ÊǺÜÇå³þ£¬·³Çë¼ÌÐøÖ¸µã

¶¥ÉÏÈ¥Èç¹ûÊǼîµÄ»°£¬ÄܰïæÃ÷ȷһϣ¬Ö¸µÄÊÇʲô¼îÄØ£¿
N£­¼×»ùÂí·ÈßøÔõÑù£¿
ÂíÉÏÆÀ·Ö
2Â¥2008-08-19 11:21:26
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

qfzhang

Òø³æ (СÓÐÃûÆø)

¡ï
xyklmu(½ð±Ò+1,VIP+0):¸Ðл´ð¸´
N-ôÇ»ùçúçêõ£Ñǰ· nhs£¬¸Õ²ÅGoogleÁËһϣ¬²¹³ä
4Â¥2008-08-19 13:57:43
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

wuselht

Ìú¸Ëľ³æ (ÕýʽдÊÖ)

N-hydroxysuccinimide/base.
Â¥ÉϵÄ˵µÄÊÇÇ°ÃæÄǸöN-hydroxysuccinimide°É£¬ÎÒÎʵÄÊǺóÃæµÄbase
5Â¥2008-08-19 21:53:14
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] Ò»Ö¾Ô¸ Î÷±±´óѧ ×Ü·Ö282 Ó¢ÓïÒ»62 Çóµ÷¼Á +7 18419759900 2026-03-25 8/400 2026-03-27 16:38 by 18419759900
[¿¼ÑÐ] 085701»·¾³¹¤³Ì£¬267Çóµ÷¼Á +9 minht 2026-03-26 9/450 2026-03-27 15:29 by licg0208
[¿¼ÑÐ] ²ÄÁÏÓ뻯¹¤£¨0856£©304ÇóBÇøµ÷¼Á +7 Çñgl 2026-03-27 7/350 2026-03-27 15:27 by JoeÂÊ
[¿¼ÑÐ] ¿¼Ñл¯Ñ§308·ÖÇóµ÷¼Á +10 ÄãºÃÃ÷ÌìÄãºÃ 2026-03-23 12/600 2026-03-27 14:43 by shangxh
[¿¼ÑÐ] һ־Ը̫ԭÀí¹¤°²È«¹¤³Ì300·Ö£¬Çóµ÷¼Á +4 0857Çóµ÷¼Á. 2026-03-24 4/200 2026-03-27 14:03 by ¾²¾²¾²¾²¾²¾²¾²¾
[¿¼ÑÐ] 322Çóµ÷¼Á +4 ÎÒÕæµÄºÜÏëѧϰ 2026-03-23 4/200 2026-03-27 13:51 by ÑîÑîÑî×Ï
[¿¼ÑÐ] 0703»¯Ñ§/290Çóµ÷¼Á/±¾¿Æ¾­Àú·á¸»/¹¤¿ÆÒ²¿É +7 µ¤ÇàÄÌ¸Ç 2026-03-26 8/400 2026-03-27 11:24 by µ¤ÇàÄ̸Ç
[¿¼ÑÐ] 315µ÷¼Á +4 0860Çóµ÷¼Á 2026-03-26 5/250 2026-03-27 11:23 by wangjy2002
[¿¼ÑÐ] ¿¼Ñе÷¼Á +9 СÀ¯ÐÂ±Ê 2026-03-26 9/450 2026-03-27 11:10 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] Çóµ÷¼Á +5 «lty 2026-03-25 6/300 2026-03-26 20:49 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] ²ÄÁϵ÷¼Á 5+4 ÏëÒªÒ»ºøÌÒ»¨Ë® 2026-03-25 10/500 2026-03-26 19:56 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] 0856Çóµ÷¼Á +8 zhn03 2026-03-25 9/450 2026-03-26 13:42 by zzll406
[¿¼ÑÐ] ×Ü·Ö293Çóµ÷¼Á +6 ¼ÓÒ»Ò»¾Å 2026-03-25 8/400 2026-03-26 13:30 by yujianx
[¿¼ÑÐ] 085600 ²ÄÁÏÓ뻯¹¤ 329·ÖÇóµ÷¼Á +9 Mr. Z 2026-03-25 9/450 2026-03-26 10:36 by baoball
[¿¼ÑÐ] 07»¯Ñ§303Çóµ÷¼Á +5 î£08 2026-03-25 5/250 2026-03-25 22:46 by 418490947
[¿¼ÑÐ] Ò»Ö¾Ô¸ÄϺ½ 335·Ö | 0856²ÄÁÏ»¯¹¤ | GPA 4.07 | ÓпÆÑо­Àú +6 cccchenso 2026-03-23 6/300 2026-03-25 22:25 by 544594351
[¿¼ÑÐ] »úеѧ˶×Ü·Ö317Çóµ÷¼Á£¡£¡£¡£¡ +4 Acaciad 2026-03-25 4/200 2026-03-25 19:59 by hanserlol
[¿¼ÑÐ] Çóµ÷¼Á +3 ÀîÀî²»·þÊä 2026-03-25 3/150 2026-03-25 13:03 by cmz0325
[¿¼ÑÐ] Ò»Ö¾Ô¸ºÓ±±¹¤Òµ´óѧ0817»¯¹¤278·ÖÇóµ÷¼Á +7 jhybd 2026-03-23 12/600 2026-03-24 09:03 by jhybd
[¿¼ÑÐ] 308Çóµ÷¼Á +3 īīĮ 2026-03-21 3/150 2026-03-22 16:54 by i_cooler
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û