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Drug Discovery Series- Handbook of Assay Development in Drug Discovery
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 Drug Discovery Series- Handbook of Assay Development in Drug Discovery Multiwell assays for drug discovery have become a staple of the scientific community. This has been led by the need to screen targets more rapidly and with more efficiency than in previous years. This has also been led by advances in chemistry allowing parallel or multiplex chemical synthesis to provide more compounds for screening. These multiwell assay formats are both in vitro and cell based and include a mixture of simple enzyme assays as well as those more complex, such as cell imaging. This handbook is designed to serve as a reference guide to all of those in discovery research who are developing assays, as well as those in the academic world who wish to know what is available to perform the assay they want as well as where to find those tools. This book will provide general guidelines as well as specific examples of each assay system. These include radiometric assays, fluorescent-based assays, reporter assays, and others, for such targets as kinases, proteases, nuclear receptors, and G-protein–coupled receptors (GPCRs). The book includes chapters from assay developers in the pharmaceutical as well as in the vendor community. It is meant as a general guidebook that one can take to the bench. It includes descriptions of methods, exact protocols used to perform such methods, and troubleshooting tools. I hope that you will find it beneficial and that use of it will provide the information and guidance that you seek. |
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2015-06-08 21:04:13, 8.54 M
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50楼2015-12-29 23:30:31
简单回复
2015-06-09 08:32
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五星好评 顶一下，感谢分享！
2015-06-09 09:34
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2015-06-09 15:45
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2015-06-09 16:20
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2015-06-09 17:02
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2015-06-09 18:30
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2015-06-09 18:46
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2015-06-09 20:22
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2015-06-10 04:14
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2015-06-10 09:18
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