24小时热门版块排行榜    

查看: 3196  |  回复: 97
【奖励】 本帖被评价86次,作者1949stone增加金币 67.2
当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖

1949stone

荣誉版主 (知名作家)


[资源] Drug Discovery Series- Handbook of Assay Development in Drug Discovery

Drug Discovery Series- Handbook of Assay Development in Drug Discovery

Drug Discovery Series- Handbook of Assay Development in Drug Discovery

Multiwell assays for drug discovery have become a staple of the scientific community. This has
been led by the need to screen targets more rapidly and with more efficiency than in previous years.
This has also been led by advances in chemistry allowing parallel or multiplex chemical synthesis
to provide more compounds for screening. These multiwell assay formats are both in vitro and cell
based and include a mixture of simple enzyme assays as well as those more complex, such as cell
imaging.  This  handbook  is  designed  to  serve  as  a  reference  guide  to  all  of  those  in  discovery
research  who  are  developing  assays,  as  well  as  those  in  the  academic  world  who  wish  to  know
what is available to perform the assay they want as well as where to find those tools. This book
will provide general guidelines as well as specific examples of each assay system. These include
radiometric assays, fluorescent-based assays, reporter assays, and others, for such targets as kinases,
proteases, nuclear receptors, and G-protein–coupled receptors (GPCRs). The book includes chapters
from assay developers in the pharmaceutical as well as in the vendor community. It is meant as a
general  guidebook  that  one  can  take  to  the  bench.  It  includes  descriptions  of  methods,  exact
protocols  used  to  perform  such  methods,  and  troubleshooting  tools.  I  hope  that  you  will  find  it
beneficial and that use of it will provide the information and guidance that you seek.
回复此楼

» 本帖附件资源列表

  • 欢迎监督和反馈:小木虫仅提供交流平台,不对该内容负责。
    本内容由用户自主发布,如果其内容涉及到知识产权问题,其责任在于用户本人,如对版权有异议,请联系邮箱:xiaomuchong@tal.com
  • 附件 1 : Handbook_of_assay_development_in_drug_discovery.pdf
  • 2015-06-08 21:04:13, 8.54 M

» 收录本帖的淘帖专辑推荐

生物医药文献书 药物合成 英语资料(生物类) 英文精华
养一斋

» 猜你喜欢

» 本主题相关价值贴推荐,对您同样有帮助:

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 1949stone 的主题更新
☆ 无星级 ★ 一星级 ★★★ 三星级 ★★★★★ 五星级
普通表情 高级回复(可上传附件)
信息提示
请填处理意见