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leirongjian铁杆木虫 (正式写手)
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Fred Hutchinson Cancer Research Center对请求接受T细胞治疗的患者的答复
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Dr. Cassian Yee's research office has received an extraordinary number of calls and e-mails as a result of extensive media coverage of his paper about T-cell therapy for advanced melanoma, which appeared in the June 19 issue of the New England Journal of Medicine. His staff is doing its best to respond to as many inquiries as possible. We are only treating patients with melanoma and it can take 4 to 5 months to grow the T cells before they can be infused. We regret that this has been disappointing to most people asking about the trial. More studies — including a much larger clinical trial — will be required to validate the findings reported in June, which were based on a single patient. Dr. Yee currently has two similar, small clinical trials under way for patients with advanced melanoma. Eligibility to participate in these trials is very strict as there are many criteria for enrollment; some of these include no brain metastasis, no other form of cancer, good performance status (can perform normal daily activities) and no other serious illnesses. We do not generally enroll patients outside of the Seattle area because close follow up is required and because the time and expense required of patients to remain in the Seattle area can pose undue hardships on patients who are away from their friends and family. Dr. Cassian Yee's研究所因为媒体对其用T细胞治疗晚期黑素瘤实验广泛报道，收到许多电话和e-mails，此前实验论文发表在新英格兰医学杂质June 19 issue上。他和同事正在尽最大努力去回复询问者。我们只是治疗黑色素瘤病人，且在患者接受注射之前需要4－5周去培育T细胞，因此对很多询问此实验的人我们深感抱歉。深入的研究包括一项更大的临床试验将被确定进行，此前的试验研究是基于一个患者的。Dr. Yee目前正在进行两项类似的针对晚期黑色素瘤患者的小规模临床试验，接受试验的患者筛选条件是相当严格的，例如不能有脑转移、没有其他形式癌症、良好的身体状态及没有其他严重疾病。因为时间上和生活上的原因及需要远离家人和朋友，我们一般不接受西雅图地区外的患者作为试验对象 |
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