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Alkimiya新虫 (小有名气)
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[求助]
帮忙查询盐酸环喷托酯的原研厂家和相关资料已有2人参与
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初入立项方面工作，恳请木虫大牛帮助~ 名字: 环喷托酯 英文名：CYCLOPENTOLATE CAS：512-15-2 很疑惑的是，在FDA上查询到最老的申请号是040075 。但是在FDA@drug上未明确其为新药。现在查不清这个药到底原研属于哪个厂家？ 请教大家这种情况怎么查询？如果还有相关市场方面的资料更好，非常感谢！  |
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Alkimiya
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2楼2015-04-25 16:10:08
cool-boy
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【答案】应助回帖
感谢参与，应助指数 +1
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简介：英文药名: Cyclogyl(Cyclopentolate Drops) 中文药名: 盐酸环喷托酯滴眼液 品牌药生产厂家: Alcon Labratories Inc. 药品名称 中文通用名称：盐酸环喷托酯 英文通用名称：Cyclopentolate Hydrochloride 中文 ... 关键字：盐酸环喷托酯滴眼液|Cyclogyl(Cyclopentolate Drops) 英文药名: Cyclogyl(Cyclopentolate Drops) 中文药名: 盐酸环喷托酯滴眼液 品牌药生产厂家: Alcon Labratories Inc. 药品名称 中文通用名称：盐酸环喷托酯 英文通用名称：Cyclopentolate Hydrochloride 中文其它名称：环喷托酯盐酸盐, 盐酸环喷托酯滴眼液, 赛飞杰, 环戊醇胺酯, 环戊通 英文其它名称：Cyclogyl, Cyclopentolate Hydrochloride Eye Drops 产品所属分类：眼科用药\其它眼科用药 药理作用 药理作用和阿托品非常相似。麻痹睫状肌的时间短、作用快而强。在仅需散瞳时，可用低浓度的环喷托酯溶液。 适应症 环喷托酯为合成的散瞳药。 不良反应 本品对儿童可致中枢神经系统紊乱，如幻觉及精神病发作，滴眼后稍有烧灼感。成人的毒性作用很少见。近来报告66例用此药2％溶液点眼，10例发生全身性反应，根据出现的先后，依次有无力、恶心、头昏、情绪改变、无故哭泣、失去平衡及心动过速。 据报告儿童及成人的周身反应，大多数是用1％溶液，提示周身反应是剂量依赖性的。因此，最好是用0.5％溶液，特别是儿童。 点眼还可出现一过性的热感，甚至有眼压亢进。中年以上患者使用时应注意。 规格: 1% 15ml 1% 3 x 5ml Medication name Generic name: Cyclopentolate Hydrochloride Solution - Ophthalmic Pronunciation: (SYE-kloe-PEN-toe-late HYE-droe-KLOR-ide) Brand name(s): Cyclogyl, Cylate, Pentolair Uses This medication is used before eye examinations (e.g., refraction exams). It belongs to a class of drugs known as anticholinergics. Cyclopentolate works by temporarily widening (dilating) the pupil of the eye and relaxing the muscles of the eye. How to use This medication is usually applied in the eye 40 to 50 minutes before the procedure or as directed by your doctor. The dose may need to be repeated in 5 to 10 minutes. This medication is for use in the eye only. Do not take by mouth or inject.To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. If you are wearing contact lenses, remove them before using eye drops. Ask your doctor when you can start wearing them again. If you are using another kind of eye medication (e.g., drops or ointments), ask your doctor when you should start using them again.Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure for 2 to 3 minutes. This will prevent the medication from draining away from the eye and reduce side effects. Try not to blink and do not rub your eye. Repeat these steps if your dose is for more than 1 drop or for your other eye if so directed.Do not rinse the dropper. Replace cap after use.If you are using this medicine in a child's eye(s), do not get any medicine in the child's mouth. Wash your hands and your child's hands after use to remove any medicine from them.This medication may temporarily change digestion in infants. Do not feed an infant for 4 hours after the infant's eye exam.This medication starts to work in minutes, and its effect usually lasts 24 hours or sometimes longer. Tell your doctor if you continue to have blurred vision, sensitivity to light, or dilated pupils several days after your exam. Precautions Before using cyclopentolate, tell your doctor or pharmacist if you are allergic to it; or to belladonna alkaloids (e.g., atropine); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: glaucoma.Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye conditions, Down's syndrome, brain damage or spastic paralysis (in children), heart disease.After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.This medication may make your eyes more sensitive to light. Protect your eyes in bright light. Use dark sunglasses when outdoors.Caution is advised when using this drug in infants or small children because they may be more sensitive to the effects of the drug, especially mental/mood changes. If using this medication in an infant, watch the infant closely for 30 minutes after the medication is applied.Caution is advised when this drug is used in the elderly since this group may be more sensitive to side effects of this drug, especially increased pressure in the eye.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding. Drug interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: eye medications for glaucoma/increased pressure in the eye (e.g., carbachol, dorzolamide, pilocarpine), certain antiarrhythmic drugs (e.g., quinidine, procainamide), antihistamines (e.g., diphenhydramine, meclizine), antispasmodics (e.g., dicyclomine), certain drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), tricyclic antidepressants (e.g., amitriptyline).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Side effects Burning/stinging/redness of the eye, eye irritation, or temporary blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, fainting, new or increased eye pressure/pain/swelling/discharge.Tell your doctor immediately if any of these rare but very serious side effects occur: slow/shallow breathing, fast/irregular heartbeat, mental/mood changes (e.g., confusion, hallucinations, restlessness, strange behavior), seizures.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Missed dose Not applicable. Overdose This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: flushed/dry skin, blurred vision, fast/irregular heartbeat, fever, mental/mood changes (e.g., hallucinations), loss of coordination. Notes Do not share this medication with others. Storage Store between 46-80 degrees F (8-27 degrees C) away from heat and light. Do not freeze. Keep all medicines away from children and pets.If you are using the single-use containers, discard any unused medication immediately after use.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Photos by medication strength Click the "Photos" link to see sample photographs for a specific medication strength. Common strengths Cyclogyl 0.5 % Eye Drops Cyclogyl 1 % Eye Drops Cyclogyl 2 % Eye Drops |
3楼2015-04-25 17:11:38
Alkimiya
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4楼2015-04-25 17:29:29
cool-boy
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5楼2015-04-26 07:16:39
wachina
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6楼2015-04-26 08:39:53
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