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Biotransformation of dianabol with the filamentous fungi and b-glucuronidase inhibitory activity of resulting metabolites

Macrophomina phaseolina    Aspergillus niger, Gibberella fujikuroi,   Cunninghamella echinulata   17 a -methyl-6b,17b-dihydroxyestr-4-en-3-one   
17 a -(hydroxy-methyl)-11b,17b-dihydroxyestr-4-en-3-one (3), 17 a -methyl-2 a ,11b,17b-trihydroxyestr-4-en-3-one (4),
17 a -methyl-1b,17b-dihydroxyestr-4-en-3-one (5), 17 a -methyl-11 a ,17b-dihydroxyestr-4-en-3-one (6),
17 a -methyl-11b,17b-dihydroxyestr-4-en-3-one (7), 17 a -methyl-10b,17b-dihydroxyestr-4-en-3-one (8),
17 a -(hydroxymethyl)-17b-hydroxyestr-4-en-3-one (9), 17 a -methylestr-1,3,5(10)-trien-3,17b-diol (10),
17 a -methyl-3,17b-dihydroxyestr-1,3,5(10)-trien-6-one (11), and 17 a -methyl-6b,10b,17b-trihydroxy-
estr-4-en-3-one (12).

a为α,b为β

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bxzc123: 金币+5, 翻译EPI+1, ★★★★★最佳答案 2015-04-25 13:52:16
Biotransformation of dianabol with the filamentous fungi and b-glucuronidase inhibitory activity of resulting metabolites
丝状真菌对羟甲雄二烯酮的生物转化及其代谢产物对β葡萄糖醛酸酶的抑制作用

Macrophomina phaseolina:菜豆立炫f菌
Aspergillus niger:黑曲霉
Gibberella fujikuroi:赤霉菌恶苗病
Cunninghamella echinulata:刺孢小克克银汉霉
17 a -methyl-6b,17b-dihydroxyestr-4-en-3-one:17α - 甲基 - 6β,17b的二羟基雌甾-4-烯-3-酮
17 a -(hydroxy-methyl)-11b,17b-dihydroxyestr-4-en-3-one:17α - (羟基 - 甲基)-11β,17b的二羟基雌甾-4-烯-3-酮
17 a -methyl-2 a ,11b,17b-trihydroxyestr-4-en-3-one :17α - 甲基 - 2α,11β,17β三羟基雌甾-4-烯-3-酮
17 a -methyl-1b,17b-dihydroxyestr-4-en-3-one:17α - 甲基-1β,17β二羟基雌甾-4-烯-3-酮
17 a -methyl-11 a ,17b-dihydroxyestr-4-en-3-one:17 - 甲基 - 11α,17β二羟基雌甾-4-烯-3-酮
17 a -methyl-11b,17b-dihydroxyestr-4-en-3-one :17α - 甲基 - 11β,17β的二羟基雌甾-4-烯-3-酮
17 a -methyl-10b,17b-dihydroxyestr-4-en-3-one:17α - 甲基 - 10β,17β二羟基雌甾-4-烯-3-酮
17 a -(hydroxymethyl)-17b-hydroxyestr-4-en-3-one:17α - (羟甲基)-17β羟基雌甾-4-烯-3-酮
17 a -methylestr-1,3,5(10)-trien-3,17b-diol:17α - 甲基雌甾-1,3,5(10) - 三烯3,17β二醇
17 a -methyl-3,17b-dihydroxyestr-1,3,5(10)-trien-6-one:17α - 甲基3,17β二羟基雌甾-1,3,5(10) - 三烯-6-酮
17 a -methyl-6b,10b,17b-trihydroxy-estr-4-en-3-one :17α - 甲基 - 6β,10β,17β三羟基雌甾-4-烯-3-酮
2楼2015-04-25 05:56:39
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