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[求助]
求助文献Food and Chemical Toxicology 78 (2015) 42–51是否被SCI收录
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作者：XinWang, Yang Liu, Ling-Ling He , Bin Liu, Si-Yi Zhang, Xiu Ye, Jiao-Jiao Jing, Jin-Feng Zhang, Ming Gao, XinWang 题目：Spectroscopic investigation on the food components–drug interaction: The influence of flavonoids on the affinity of nifedipine to human serum albumin 期刊：Food and Chemical Toxicology 78 (2015) 42–51 请将检索结果粘贴，多谢了。 |
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tangcwk
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【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★
helingling: 金币+10, 多谢了 2015-04-10 22:11:13
心静_依然: LS-EPI+1, 感谢应助 2015-04-10 22:11:39
helingling: 金币+10, 多谢了 2015-04-10 22:11:13
心静_依然: LS-EPI+1, 感谢应助 2015-04-10 22:11:39
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第 1 条，共 1 条 标题: Spectroscopic investigation on the food components-drug interaction: The influence of flavonoids on the affinity of nifedipine to human serum albumin. 作者: Wang, Xin; Liu, Yang; He, Ling-Ling; Liu, Bin; Zhang, Si-Yi; Ye, Xiu; Jing, Jiao-Jiao; Zhang, Jin-Feng; Gao, Ming; Wang, Xin 来源出版物: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 卷: 78 页: 42-51 DOI: 10.1016/j.fct.2015.01.026 出版年: 2015-Apr 摘要: Nifedipine (NDP) is used extensively for the clinical treatment of a number of cardiovascular diseases. Herein, the interaction between human serum albumin (HSA) and NDP and the influence of flavonoids, rutin and baicalin, on their binding properties were investigated in vitro by means of fluorescence and absorption spectroscopy. The fluorescence of HSA was quenched remarkably by NDP and the quenching mechanism was considered as static quenching by forming a complex. The results of thermodynamic parameters indicate that both hydrogen bonds and hydrophobic interactions play the main role in the binding process and the binding process was spontaneous. The binding distance between the amino acid residue of HSA and NDP is 2.608nm, which indicates that the energy transfer from HSA to NDP can occur with high probability. The decreased association constants and the increased binding distance of NDP binding to HSA in the presence of flavonoids were both due to their competitive binding to the site I of HSA. The results obtained from synchronous fluorescence and three-dimensional fluorescence spectra showed that the interaction between HSA and NDP caused the conformational changes of HSA and the synergism effects of NDP and flavonoids induced the further conformational changes of HSA. Copyright 2015 Elsevier Ltd. All rights reserved. PubMed ID: 25656645 文献类型: Journal Article 语种: English 地址: School of Pharmaceutical Sciences, Liaoning University, Shenyang 110036, China. 分主题子库: Index Medicus 关键词列表: Flavonoids; Fluorescence spectroscopy; Food components-drug interaction; Human serum albumin; Nifedipine ISSN: 1873-6351 NLM 唯一 ID: 8207483 国家/地区: England 状态: In-Data-Review 创建日期: 23 Mar 2015 电子出版: 02 Feb 2015 但是被Index Medicus子库收录 实际上还未被SCI收录 现在Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association这个期刊收录到 卷: 77 你的估计快了 |
4楼2015-04-10 21:38:30
tangcwk
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2楼2015-04-10 21:35:52
baiyuefei
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【答案】应助回帖
感谢参与，应助指数 +1
心静_依然: 应助指数-1, 非有效应助 2015-04-10 22:07:01
心静_依然: 应助指数+1, 不好意思，以为只是个普通注册链接，点进去是检索结果页，以后还是复制一下信息比较好，希望谅解 2015-04-10 22:42:10
心静_依然: 应助指数-1, 非有效应助 2015-04-10 22:07:01
心静_依然: 应助指数+1, 不好意思，以为只是个普通注册链接，点进去是检索结果页，以后还是复制一下信息比较好，希望谅解 2015-04-10 22:42:10
3楼2015-04-10 21:36:02
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