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2Â¥2015-04-08 08:00:43
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4Â¥2015-04-08 10:56:37
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5Â¥2015-04-08 13:51:07
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7Â¥2015-04-08 15:12:38
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1. My major concern is the lack detail in the results reported in Tables 1 to 3, and particularly the absence of any statistical analysis of these results. While 10 fold cross-validation has been used, the only results reported are the mean values achieved by each method across these 10 trials. No values are reported indicating the variance in algorithmic performance, either in terms of standard deviation or max/min values. Similarity there has been no testing of the statistical significance of the improvement in accuracy and reduction in number of genes observed for WDRSVM - such testing should be possible given that 10 trials have been run. 2. Reporting accuracy at a per-class level (ie true positives and true negatives) would also provide further insight into the performance of each method. 3. I also note that the fact that 10-fold validation was used was not immediately obvious, as the discussion as the initial discussion on lines 316-318 seemed to suggest that fixed training and testing samples were used, and this impression was not rectified until lines 339-340 - it would be useful to state this more clearly earlier in the paper. °ÝÍаïÎÒ¿´¿´°É¡£¡£¡£ |
8Â¥2015-04-08 17:36:48
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9Â¥2015-04-08 17:38:22
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10Â¥2015-04-08 17:42:49













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