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【答案】应助回帖
★ ★ ★ ★ ★ ★
感谢参与，应助指数 +1
zch79214: 金币+6, ★★★★★最佳答案 2015-02-25 16:22:16
oven1986: LS-EPI+1, 感谢应助。 2015-02-25 23:52:56
是的，举例如下：
Accession number:
20150700506454
Article in Press
Title:
Polyphenol contents of five of medicinal plants from Cameroon and effects of their extracts on antioxidant capacities of human breast cancer cells
Authors:
Pieme, Constant Anatole1, 2 ; Ngogang, Jeanne1; Costache, Marieta2
Author affiliation:
1Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaound I, Yaounde, Cameroon
2Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, Bucharest, Romania
Corresponding author:
Pieme, Constant Anatole
Source title:
Toxicological and Environmental Chemistry
Abbreviated source title:
Toxicol. Environ. Chem.
Issue date:
January 1, 2015
Publication year:
2015
Language:
English
ISSN:
02772248
E-ISSN:
10290486
CODEN:
TECSDY
Document type:
Article in Press
Publisher:
Taylor and Francis Ltd.
Abstract:
The aim of the study was to investigate the antiproliferative properties of extracts of five plants on breast cancer cells (MDA-MB-231) and their effects on antioxidant activities. The total phenol contents of the extracts were determined to establish a correlation to their antiproliferative effects which were evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide viability assay. Enzymes involved in oxidative stress were also determined. Total polyphenol contents of the five extracts varied from 170 to 440 mg L−1 of gallic acid per mg of extract with the highest value for the extract of Sida cordifolia. Cell growth inhibition was observed within 24 h, with inhibitory concentration values ranging from 7.3 to 25 mg L−1 depending on plant extract. At concentrations between 100 and 200 mg L−1, all the extracts exhibited significant reduction of cell proliferation in time-dependent and linear manner. The activities of superoxide dismutase and catalase of cells treated for 24 h with the extract of S. cordifolia were 3.5 U per mg protein and 8 mole H2O2 consumed per min per mg protein higher than those of cells treated with an extract of Viscum album. © 2015 Taylor & Francis
Page count:
11
Main heading:
Plant extracts
Controlled terms:
Antioxidants - Cell proliferation - Cells - Cytology - Diseases - Oxygen - Plants (botany) - Proteins
Uncontrolled terms:
Anti-oxidant activities - Anti-proliferative - Lorantaceae - Malvaceae - morantaceae - Polyphenols
Classification code:
461 Bioengineering and Biology - 804 Chemical Products Generally - 804.1 Organic Compounds
DOI:
10.1080/02772248.2014.999680
Database:
Compendex
Compilation and indexing terms, © 2015 Elsevier Inc.
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