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http://www.souku.com.cn/viewtitle.jsp?url=3771242 CAS登记号：106-89-8----化学品毒性数据库 [ Last edited by zzgyb on 2008-7-22 at 08:35 ] |
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IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,131,1976 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,202,1987 IARC Cancer Review:Group 2A IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,202,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 5 ppm (19 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,98,1971 OSHA PEL (Gen Indu):8H TWA 5 ppm (19 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 ppm (19 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 ppm (19 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 ppm (19 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-AUSTRALIA:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 2 ppm (7.6 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.5 ppm (1.9 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 0.5 ppm (1.9 mg/m3);Skin;Carcinogen JAN 1993 OEL-FRANCE:STEL 2 ppm (10 mg/m3);Carcinogen JAN 1993 OEL-GERMANY;Skin;Carcinogen JAN 1993 OEL-HUNGARY:STEL 1 mg/m3;Skin;Carcinogen JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (4 mg/m3);STEL 4 ppm;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 5 ppm (19 mg/m3);Skin JAN 1993 OEL-POLAND:TWA 1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.5 ppm (1.9 mg/m3);STEL 1 ppm (4 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 2 ppm (8 mg/m3);Skin;Carcinogen JAN 1993 OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 2 ppm (8 mg/m3);STEL 5 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO EPICHLOROHYDRIN-air:CA lowest feasible concentration REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 29010 No. of Facilities: 2004 (estimated) No. of Industries: 40 No. of Occupations: 58 No. of Employees: 41380 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 29010 No. of Facilities: 4249 (estimated) No. of Industries: 75 No. of Occupations: 87 No. of Employees: 80170 (estimated) No. of Female Employees: 14921 (estimated) *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat EPA GENETOX PROGRAM 1988, Positive: In vitro cytogenetics-human lymphocyte EPA GENETOX PROGRAM 1988, Positive: In vivo cytogenetics-human lymphocyte EPA GENETOX PROGRAM 1988, Positive: N crassa-forward mutation; N crassa-reversion EPA GENETOX PROGRAM 1988, Positive: E coli polA without S9; Histidine reversion-Ames test EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal; S pombe-forward mutation EPA GENETOX PROGRAM 1988, Positive: S pombe-reversion EPA GENETOX PROGRAM 1988, Negative: Sperm morphology-human; Sperm morphology-mouse EPA GENETOX PROGRAM 1988, Inconclusive: Mammalian micronucleus EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 47,26992,82 EPA TSCA Section 8(d) unpublished health/safety studies On EPA IRIS database EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 NIOSH CURRENT INTELLIGENCE BULLETIN 30, 1978 NIOSH Analytical Method, 1994: Epichlorohydrin, 1010 NTP 7th Annual Report on Carcinogens, 1992 : anticipated to be carcinogen *** END OF RECORD *** |
10楼2008-06-06 17:31:26
我是一只小马甲
铁杆木虫 (知名作家)
明天跟xww去肯尼亚放牛
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3楼2008-06-06 17:05:32
我是一只小马甲
铁杆木虫 (知名作家)
明天跟xww去肯尼亚放牛
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4楼2008-06-06 17:07:25
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106-89-8 *** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TX4900000 CHEMICAL NAME : Propane, 1-chloro-2,3-epoxy- CAS REGISTRY NUMBER : 106-89-8 BEILSTEIN REFERENCE NO. : 0079785 REFERENCE : 5-17-01-00020 (Beilstein Handbook Reference) LAST UPDATED : 199801 DATA ITEMS CITED : 144 MOLECULAR FORMULA : C3-H5-Cl-O MOLECULAR WEIGHT : 92.53 WISWESSER LINE NOTATION : T3OTJ B1G COMPOUND DESCRIPTOR : Agricultural Chemical Tumorigen Mutagen Reproductive Effector Human Primary Irritant SYNONYMS/TRADE NAMES : * 1-Chloor-2,3-epoxy-propaan * 1-Chlor-2,3-epoxy-propan * 1-Chloro-2,3-epoxypropane * 3-Chloro-1,2-epoxypropane * 1-Chloro-2,3-epoxypropane * epi-Chlorohydrin * (Chloromethyl)ethylene oxide * Chloromethyloxirane * 2-(Chloromethyl)oxirane * 3-Chloro-1,2-propane oxide * Chloropropylene oxide * gamma-Chloropropylene oxide * 3-Chloro-1,2-propylene oxide * 1-Cloro-2,3-epossipropano * ECH * Epichloorhydrine * Epichlorhydrin * Epichlorhydrine * Epichlorohydrin * alpha-Epichlorohydrin * (DL)-alpha-Epichlorohydrin * Epichlorohydryna * Epichlorophydrin * Epicloridrina * 1,2-Epoxy-3-chloropropane * 2,3-Epoxypropyl chloride * Glycerol epichlorhydrin * Oxirane, (chloromethyl)- * Oxirane, 2-(chloromethyl) * RCRA waste number U041 * Skekhg *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Open irritation test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 10 mg/24H REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg REACTION SEVERITY : Severe REFERENCE : AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg/24H REACTION SEVERITY : Moderate REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,769,1986 ** ACUTE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Human DOSE/DURATION : 40 ppm/2H TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,240,1969 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Human DOSE/DURATION : 20 ppm TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified REFERENCE : 29ZWAE "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968 Volume(issue)/page/year: -,108,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 ppm/8H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,41,1974 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Skin and Appendages - hair REFERENCE : UCPHAQ University of California, Berkeley, Publications in Pharmacology. (Berkeley, CA) V.1-3, 1938-57. Discontinued. Volume(issue)/page/year: 2,69,1941 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 133 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 52,422,1980 |
5楼2008-06-06 17:29:11